Protein Tyrosine Phosphatase, Non-Receptor Type 22
"Protein Tyrosine Phosphatase, Non-Receptor Type 22" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.
Descriptor ID |
D054596
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MeSH Number(s) |
D08.811.277.352.650.775.300.930 D12.644.360.585.930 D12.776.476.564.930
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Concept/Terms |
Protein Tyrosine Phosphatase, Non-Receptor Type 22- Protein Tyrosine Phosphatase, Non-Receptor Type 22
- Protein Tyrosine Phosphatase, Non Receptor Type 22
- PTPase Lyp
- Lymphoid Phosphatase
- Tyrosine Protein Phosphatase, Non-Receptor Type 22
- Tyrosine Protein Phosphatase, Non Receptor Type 22
- PTPN-22 Protein
- PTPN 22 Protein
- Protein-Tyrosine Phosphatase Lyp
- Protein Tyrosine Phosphatase Lyp
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Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 22".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 22".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 22" by people in this website by year, and whether "Protein Tyrosine Phosphatase, Non-Receptor Type 22" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatase, Non-Receptor Type 22" by people in Profiles.
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Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarc?n GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, Reveille JD, Vil? LM, Boackle SA, Freedman BI, Tsao BP, Langefeld CD, Vyse TJ, Jacob CO, Pons-Estel B, Niewold TB, Moser Sivils KL, Merrill JT, Anaya JM, Gilkeson GS, Gaffney PM, Bae SC, Alarc?n-Riquelme ME, Harley JB, Criswell LA, James JA, Nath SK. PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013; 8(8):e69404.