Interleukin-1alpha

"Interleukin-1alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.

Descriptor ID	D053582
MeSH Number(s)	D12.644.276.374.465.010.300 D12.644.276.374.500.400.300 D12.776.467.374.465.010.300 D12.776.467.374.500.400.300 D23.529.374.465.131.300 D23.529.374.500.400.300
Concept/Terms	Interleukin-1alpha Interleukin-1alpha Interleukin 1alpha IL-1 alpha Interleukin-1 alpha Interleukin 1 alpha Hematopoietin-1 Hematopoietin 1

Below are MeSH descriptors whose meaning is more general than "Interleukin-1alpha".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-1 [D12.644.276.374.465.010]
Interleukin-1alpha [D12.644.276.374.465.010.300]
Monokines [D12.644.276.374.500]
Interleukin-1 [D12.644.276.374.500.400]
Interleukin-1alpha [D12.644.276.374.500.400.300]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-1 [D12.776.467.374.465.010]
Interleukin-1alpha [D12.776.467.374.465.010.300]
Monokines [D12.776.467.374.500]
Interleukin-1 [D12.776.467.374.500.400]
Interleukin-1alpha [D12.776.467.374.500.400.300]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-1 [D23.529.374.465.131]
Interleukin-1alpha [D23.529.374.465.131.300]
Monokines [D23.529.374.500]
Interleukin-1 [D23.529.374.500.400]
Interleukin-1alpha [D23.529.374.500.400.300]

Below are MeSH descriptors whose meaning is related to "Interleukin-1alpha".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-1alpha".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-1alpha" by people in this website by year, and whether "Interleukin-1alpha" was a major or minor topic of these publications.

Bar chart showing 10 publications over 8 distinct years, with a maximum of 2 publications in 2014 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	1	0	1
2012	1	0	1
2013	0	1	1
2014	0	2	2
2015	1	1	2
2017	1	0	1
2019	0	1	1
2020	1	0	1

Below are the most recent publications written about "Interleukin-1alpha" by people in Profiles.

Shi L, Song L, Maurer K, Dou Y, Patel VR, Su C, Leonard ME, Lu S, Hodge KM, Torres A, Chesi A, Grant SFA, Wells AD, Zhang Z, Petri MA, Sullivan KE. IL-1 Transcriptional Responses to Lipopolysaccharides Are Regulated by a Complex of RNA Binding Proteins. J Immunol. 2020 03 01; 204(5):1334-1344.

View in: PubMed
Avotri S, Eatman D, Russell-Randall K. Effects of Resveratrol on Inflammatory Biomarkers in Glaucomatous Human Trabecular Meshwork Cells. Nutrients. 2019 Apr 30; 11(5).

View in: PubMed
Bauer D, Redmon N, Mazzio E, Soliman KF. Apigenin inhibits TNFa/IL-1a-induced CCL2 release through IKBK-epsilon signaling in MDA-MB-231 human breast cancer cells. PLoS One. 2017; 12(4):e0175558.

View in: PubMed
Odewumi C, Latinwo LM, Sinclair A, Badisa VL, Abdullah A, Badisa RB. Effect of cadmium on the expression levels of interleukin-1a and interleukin-10 cytokines in human lung cells. Mol Med Rep. 2015 Nov; 12(5):6422-6.

View in: PubMed
Odewumi CO, Latinwo LM, Ruden ML, Badisa VL, Fils-Aime S, Badisa RB. Modulation of cytokines and chemokines expression by NAC in cadmium chloride treated human lung cells. Environ Toxicol. 2016 Nov; 31(11):1612-1619.

View in: PubMed
Sasi SP, Song J, Park D, Enderling H, McDonald JT, Gee H, Garrity B, Shtifman A, Yan X, Walsh K, Natarajan M, Kishore R, Goukassian DA. TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. J Biol Chem. 2014 May 16; 289(20):14178-93.

View in: PubMed
Gangapuram M, Mazzio E, Eyunni S, Soliman KF, Redda KK. Synthesis and biological evaluation of substituted N-[3-(1H-pyrrol-1-yl)methyl]-1,2,5,6-tetrahydropyridin-1-yl]benzamide/benzene sulfonamides as anti-inflammatory agents. Arch Pharm (Weinheim). 2014 May; 347(5):360-9.

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Casson CN, Copenhaver AM, Zwack EE, Nguyen HT, Strowig T, Javdan B, Bradley WP, Fung TC, Flavell RA, Brodsky IE, Shin S. Caspase-11 activation in response to bacterial secretion systems that access the host cytosol. PLoS Pathog. 2013; 9(6):e1003400.

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Driss A, Wilson NO, Mason K, Hyacinth HI, Hibbert JM, Serjeant GR, Stiles JK. Elevated IL-1a and CXCL10 serum levels occur in patients with homozygous sickle cell disease and a history of acute splenic sequestration. Dis Markers. 2012; 32(5):295-300.

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Son DS, Roby KF. Interleukin-1alpha-induced chemokines in mouse granulosa cells: impact on keratinocyte chemoattractant chemokine, a CXC subfamily. Mol Endocrinol. 2006 Nov; 20(11):2999-3013.

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