"Phospholipase C gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoinositide phospholipase C subtype that is primarily regulated by PROTEIN-TYROSINE KINASES. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of SRC HOMOLOGY DOMAINS and pleckstrin homology domains located between two halves of the CATALYTIC DOMAIN.
| Descriptor ID |
D051966
|
| MeSH Number(s) |
D08.811.277.352.640.700.700.562.750 D12.644.360.571.750 D12.776.476.556.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Phospholipase C gamma".
Below are MeSH descriptors whose meaning is more specific than "Phospholipase C gamma".
This graph shows the total number of publications written about "Phospholipase C gamma" by people in this website by year, and whether "Phospholipase C gamma" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Phospholipase C gamma" by people in Profiles.
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Hu X, Li S, Doycheva DM, Huang L, Lenahan C, Liu R, Huang J, Gao L, Tang J, Zuo G, Zhang JH. Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE. Oxid Med Cell Longev. 2020; 2020:6801587.
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Timsah Z, Ahmed Z, Ivan C, Berrout J, Gagea M, Zhou Y, Pena GN, Hu X, Vallien C, Kingsley CV, Lu Y, Hancock JF, Liu J, Gladden AB, Mills GB, Lopez-Berestein G, Hung MC, Sood AK, Bogdanov M, Ladbury JE. Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer. Oncogene. 2016 04 28; 35(17):2186-96.
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Ghose R. A measured approach: determining the PLC?1 docking site on Itk using a biochemical ruler. J Mol Biol. 2013 Feb 22; 425(4):679-82.
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Caglayan E, Vantler M, Lepp?nen O, Gerhardt F, Mustafov L, Ten Freyhaus H, Kappert K, Odenthal M, Zimmermann WH, Tallquist MD, Rosenkranz S. Disruption of platelet-derived growth factor-dependent phosphatidylinositol 3-kinase and phospholipase C? 1 activity abolishes vascular smooth muscle cell proliferation and migration and attenuates neointima formation in vivo. J Am Coll Cardiol. 2011 Jun 21; 57(25):2527-38.
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Hunter I, Mascall KS, Ramos JW, Nixon GF. A phospholipase C?1-activated pathway regulates transcription in human vascular smooth muscle cells. Cardiovasc Res. 2011 Jun 01; 90(3):557-64.
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Shannon LA, Calloway PA, Welch TP, Vines CM. CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes. J Biol Chem. 2010 Dec 10; 285(50):38781-7.
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Suzuki Y, Yoshimaru T, Matsui T, Inoue T, Niide O, Nunomura S, Ra C. Fc epsilon RI signaling of mast cells activates intracellular production of hydrogen peroxide: role in the regulation of calcium signals. J Immunol. 2003 Dec 01; 171(11):6119-27.
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Suzuki Y, Yoshimaru T, Matsui T, Ra C. Silver activates calcium signals in rat basophilic leukemia-2H3 mast cells by a mechanism that differs from the Fc epsilon RI-activated response. J Immunol. 2002 Oct 01; 169(7):3954-62.