"Cyclooxygenase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
| Descriptor ID |
D051546
|
| MeSH Number(s) |
D08.811.600.720.750
|
| Concept/Terms |
Cyclooxygenase 2- Cyclooxygenase 2
- Cyclo-Oxygenase II
- Cyclo Oxygenase II
- PTGS2
- PGHS-2
- Prostaglandin H Synthase-2
- Prostaglandin H Synthase 2
- COX-2 Prostaglandin Synthase
- COX 2 Prostaglandin Synthase
- Prostaglandin Synthase, COX-2
- Synthase, COX-2 Prostaglandin
- Cyclooxygenase-2
|
Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase 2".
Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase 2".
This graph shows the total number of publications written about "Cyclooxygenase 2" by people in this website by year, and whether "Cyclooxygenase 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 7 | 7 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 7 | 7 |
| 2005 | 1 | 8 | 9 |
| 2006 | 2 | 5 | 7 |
| 2007 | 4 | 2 | 6 |
| 2008 | 1 | 2 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 4 | 4 |
| 2011 | 4 | 1 | 5 |
| 2012 | 4 | 3 | 7 |
| 2013 | 2 | 3 | 5 |
| 2015 | 0 | 2 | 2 |
| 2016 | 2 | 2 | 4 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 3 | 4 |
| 2019 | 0 | 4 | 4 |
| 2021 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cyclooxygenase 2" by people in Profiles.
-
Liu Q, Li L, Zheng D, Jin S, Guan X, Fu Z, Xiong Z, Ding H. Mechanism of ShuiJingDan in Treating Acute Gouty Arthritis Flares Based on Network Pharmacology and Molecular Docking. Drug Des Devel Ther. 2023; 17:3493-3505.
-
Kaushal JB, Shukla V, Sankhwar P, Jha RK, Dwivedi A. Targeted inhibition of TAK1 abrogates TGF?1 non-canonical signaling axis, NF?B/Smad7 inhibiting human endometriotic cells proliferation and inducing cell death involving autophagy. Cytokine. 2021 12; 148:155700.
-
Wu KK. Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis. Int J Mol Sci. 2021 Apr 26; 22(9).
-
Wu PT, Su WR, Li CL, Hsieh JL, Ma CH, Wu CL, Kuo LC, Jou IM, Chen SY. Inhibition of CD44 induces apoptosis, inflammation, and matrix metalloproteinase expression in tendinopathy. J Biol Chem. 2019 12 27; 294(52):20177-20184.
-
Anand P, Filipenko P, Huaman J, Lyudmer M, Hossain M, Santamaria C, Huang K, Ogunwobi OO, Holford M. Selective Inhibition of Liver Cancer Cells Using Venom Peptide. Mar Drugs. 2019 Oct 17; 17(10).
-
Burks SR, Lorsung RM, Nagle ME, Tu TW, Frank JA. Focused ultrasound activates voltage-gated calcium channels through depolarizing TRPC1 sodium currents in kidney and skeletal muscle. Theranostics. 2019; 9(19):5517-5531.
-
Gao C, Xiao G, Piersigilli A, Gou J, Ogunwobi O, Bargonetti J. Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells. Breast Cancer Res. 2019 01 14; 21(1):5.
-
Schexnayder C, Broussard K, Onuaguluchi D, Poch? A, Ismail M, McAtee L, Llopis S, Keizerweerd A, McFerrin H, Williams C. Metformin Inhibits Migration and Invasion by Suppressing ROS Production and COX2 Expression in MDA-MB-231 Breast Cancer Cells. Int J Mol Sci. 2018 Nov 21; 19(11).
-
Adedara IA, Anao OO, Forcados GE, Awogbindin IO, Agbowo A, Ola-Davies OE, Patlolla AK, Tchounwou PB, Farombi EO. Low doses of multi-walled carbon nanotubes elicit hepatotoxicity in rats with markers of oxidative stress and induction of pro-inflammatory cytokines. Biochem Biophys Res Commun. 2018 09 18; 503(4):3167-3173.
-
Ma CH, Chiua YC, Wu CH, Jou IM, Tu YK, Hung CH, Hsieh PL, Tsai KL. Homocysteine causes dysfunction of chondrocytes and oxidative stress through repression of SIRT1/AMPK pathway: A possible link between hyperhomocysteinemia and osteoarthritis. Redox Biol. 2018 05; 15:504-512.