Lymphohistiocytosis, Hemophagocytic

"Lymphohistiocytosis, Hemophagocytic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of related disorders characterized by LYMPHOCYTOSIS; HISTIOCYTOSIS; and hemophagocytosis. The two major forms are familial and reactive.

Descriptor ID	D051359
MeSH Number(s)	C15.604.250.410.575
Concept/Terms	Lymphohistiocytosis, Hemophagocytic Lymphohistiocytosis, Hemophagocytic Hemophagocytic Lymphohistiocytoses Hemophagocytic Lymphohistiocytosis Lymphohistiocytoses, Hemophagocytic Hemophagocytic Syndromes Hemophagocytic Syndrome Familial Hemophagocytic Lymphocytosis Familial Hemophagocytic Lymphocytosis Familial Hemophagocytic Lymphocytoses Hemophagocytic Lymphocytoses, Familial Hemophagocytic Lymphocytosis, Familial Lymphocytoses, Familial Hemophagocytic Lymphocytosis, Familial Hemophagocytic Familial Erythrophagocytic Lymphohistiocytosis Familial Histiocytic Reticulosis Familial Histiocytic Reticuloses Histiocytic Reticuloses, Familial Histiocytic Reticulosis, Familial Reticuloses, Familial Histiocytic Hemophagocytic Lymphohistiocytosis Familial -1 Hemophagocytic Lymphohistiocytosis Familial 1 Hemophagocytic Lymphohistiocytosis, Familial Familial Hemophagocytic Lymphohistiocytoses Hemophagocytic Lymphohistiocytoses, Familial Lymphohistiocytoses, Familial Hemophagocytic Lymphohistiocytosis, Familial Hemophagocytic Primary Hemophagocytic Hymphohistiocytosis Hemophagocytic Hymphohistiocytoses, Primary Hemophagocytic Hymphohistiocytosis, Primary Hymphohistiocytoses, Primary Hemophagocytic Hymphohistiocytosis, Primary Hemophagocytic Primary Hemophagocytic Hymphohistiocytoses Hemophagocytic Reticulosis, Familial Familial Hemophagocytic Reticuloses Hemophagocytic Reticuloses, Familial Reticuloses, Familial Hemophagocytic Reticulosis, Familial Hemophagocytic Primary Hemophagocytic Lymphohistiocytosis Hemophagocytic Lymphohistiocytoses, Primary Hemophagocytic Lymphohistiocytosis, Primary Lymphohistiocytoses, Primary Hemophagocytic Lymphohistiocytosis, Primary Hemophagocytic Primary Hemophagocytic Lymphohistiocytoses Reticulosis, Familial Histiocytic Familial Hemophagocytic Lymphohistiocytosis Familial Hemophagocytic Histiocytosis Familial Hemophagocytic Histiocytoses Hemophagocytic Histiocytoses, Familial Hemophagocytic Histiocytosis, Familial Histiocytoses, Familial Hemophagocytic Histiocytosis, Familial Hemophagocytic Familial Hemophagocytic Reticulosis Erythrophagocytic Lymphohistiocytosis, Familial Erythrophagocytic Lymphohistiocytoses, Familial Familial Erythrophagocytic Lymphohistiocytoses Lymphohistiocytoses, Familial Erythrophagocytic Lymphohistiocytosis, Familial Erythrophagocytic Hemophagocytic Lymphohistiocytosis, Familial, 1 Reactive Hemophagocytic Syndrome Reactive Hemophagocytic Syndrome Hemophagocytic Syndrome, Reactive Hemophagocytic Syndrome, Infection-Associated Hemophagocytic Syndrome, Infection Associated Infection-Associated Hemophagocytic Syndrome

Below are MeSH descriptors whose meaning is more general than "Lymphohistiocytosis, Hemophagocytic".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Lymphatic Diseases [C15.604]
Histiocytosis [C15.604.250]
Histiocytosis, Non-Langerhans-Cell [C15.604.250.410]
Lymphohistiocytosis, Hemophagocytic [C15.604.250.410.575]

Below are MeSH descriptors whose meaning is related to "Lymphohistiocytosis, Hemophagocytic".

Below are MeSH descriptors whose meaning is more specific than "Lymphohistiocytosis, Hemophagocytic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lymphohistiocytosis, Hemophagocytic" by people in this website by year, and whether "Lymphohistiocytosis, Hemophagocytic" was a major or minor topic of these publications.

Bar chart showing 12 publications over 7 distinct years, with a maximum of 3 publications in 2021 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2010	1	0	1
2012	1	0	1
2014	0	1	1
2019	1	0	1
2021	3	0	3
2023	3	0	3
2024	2	0	2

Below are the most recent publications written about "Lymphohistiocytosis, Hemophagocytic" by people in Profiles.

Gallo PM, Kim J, McNerney KO, Diorio C, Foley C, Kagami L, Wagner K, Petrosa WL, Conlon H, Gollomp KL, Canna SW, Seif AE, Conrad MA, Kelsen JR, Romberg N, Bassiri H, Sullivan KE, Teachey DT, Paessler ME, Behrens EM, Lambert MP. Serum cytokine panels in pediatric clinical practice. J Allergy Clin Immunol. 2025 Feb; 155(2):594-604.e5.

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Govindarajan A, Venter F, Chaudhry A, Kaur H, Cobos E, Petersen G. Colorectal Carcinoma-An Anomalous Trigger of Adult Hemophagocytic Lymphohistiocytosis. J Investig Med High Impact Case Rep. 2024 Jan-Dec; 12:23247096241273131.

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Chen JH, Arceri T, Datta R, Sullivan KE. Delayed post-COVID-19 hemophagocytic lymphohistiocytosis in patient with XIAP deficiency. Pediatr Allergy Immunol. 2023 09; 34(9):e14028.

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Bragg MA, Breaux WA, M'Koma AE. Inflammatory Bowel Disease-Associated Colorectal Cancer: Translational and Transformational Risks Posed by Exogenous Free Hemoglobin Alpha Chain, A By-Product of Extravasated Erythrocyte Macrophage Erythrophagocytosis. Medicina (Kaunas). 2023 07; 59(7).

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Govindarajan A, Sous R, Venter F, Torrico T, Karapetians N, Heidari A, Cobos E, Petersen G. A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge. J Investig Med High Impact Case Rep. 2023 Jan-Dec; 11:23247096231156007.

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Otto WR, Behrens EM, Teachey DT, Lamson DM, Barrett DM, Bassiri H, Lambert MP, Mount S, Petrosa WL, Romberg N, Sullivan KE, Topjian AA, Fisher BT, Kajon AE. Human Adenovirus 7-Associated Hemophagocytic Lymphohistiocytosis-like Illness: Clinical and Virological Characteristics in a Cluster of Five Pediatric Cases. Clin Infect Dis. 2021 10 05; 73(7):e1532-e1538.

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Si SJ, Tasian SK, Bassiri H, Fisher BT, Atalla J, Patel R, Romberg N, Lambert MP, Paessler M, Behrens EJ, Teachey DT, Sullivan KE. Diagnostic Challenges in Pediatric Hemophagocytic Lymphohistiocytosis. J Clin Immunol. 2021 08; 41(6):1213-1218.

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Triebwasser MP, Barrett DM, Bassiri H, Bunin N, Elgarten C, Freedman J, Geera AS, Monos D, Lambert MP, Olson T, Seif AE, Paessler M, Petrosa W, Reilly AF, Romberg N, Sullivan KE, Quinn GZ, Behrens E, Teachey DT. Combined use of emapalumab and ruxolitinib in a patient with refractory hemophagocytic lymphohistiocytosis was safe and effective. Pediatr Blood Cancer. 2021 07; 68(7):e29026.

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Morimoto A, Uchida K, Chambers JK, Sato K, Hong J, Sanjoba C, Matsumoto Y, Yamagishi J, Goto Y. Hemophagocytosis induced by Leishmania donovani?infection is beneficial to parasite survival within macrophages. PLoS Negl Trop Dis. 2019 11; 13(11):e0007816.

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Canna SW, Costa-Reis P, Bernal WE, Chu N, Sullivan KE, Paessler ME, Behrens EM. Brief report: alternative activation of laser-captured murine hemophagocytes. Arthritis Rheumatol. 2014 Jun; 66(6):1666-71.

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