Sodium Potassium Chloride Symporter Inhibitors
"Sodium Potassium Chloride Symporter Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.
| Descriptor ID |
D049994
|
| MeSH Number(s) |
D27.505.519.562.906 D27.505.696.560.500.931
|
| Concept/Terms |
Sodium Potassium Chloride Symporter Inhibitors- Sodium Potassium Chloride Symporter Inhibitors
- Na-K-CL Symporter Inhibitors
- Inhibitors, Na-K-CL Symporter
- Na K CL Symporter Inhibitors
- Symporter Inhibitors, Na-K-CL
- Sodium Potassium Chloride Cotransporter Inhibitors
- Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors
- Bumetanide Sensitive Na K Cl Transporter Inhibitors
|
Below are MeSH descriptors whose meaning is more general than "Sodium Potassium Chloride Symporter Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Sodium Potassium Chloride Symporter Inhibitors".
This graph shows the total number of publications written about "Sodium Potassium Chloride Symporter Inhibitors" by people in this website by year, and whether "Sodium Potassium Chloride Symporter Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sodium Potassium Chloride Symporter Inhibitors" by people in Profiles.
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Araujo M, Welch WJ, Zhou X, Sullivan K, Walsh S, Pasternak A, Wilcox CS. Inhibition of ROMK blocks macula densa tubuloglomerular feedback yet causes renal vasoconstriction in anesthetized rats. Am J Physiol Renal Physiol. 2017 06 01; 312(6):F1120-F1127.
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Felker GM, Lee KL, Bull DA, Redfield MM, Stevenson LW, Goldsmith SR, LeWinter MM, Deswal A, Rouleau JL, Ofili EO, Anstrom KJ, Hernandez AF, McNulty SE, Velazquez EJ, Kfoury AG, Chen HH, Givertz MM, Semigran MJ, Bart BA, Mascette AM, Braunwald E, O'Connor CM. Diuretic strategies in patients with acute decompensated heart failure. N Engl J Med. 2011 Mar 03; 364(9):797-805.
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Dai Y, Tang J, Zhang JH. Role of Cl- in cerebral vascular tone and expression of Na+-K+-2Cl- co-transporter after neonatal hypoxia-ischemia. Can J Physiol Pharmacol. 2005 Aug-Sep; 83(8-9):767-73.
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Iwamoto LM, Fujiwara N, Nakamura KT, Wada RK. Na-K-2Cl cotransporter inhibition impairs human lung cellular proliferation. Am J Physiol Lung Cell Mol Physiol. 2004 Sep; 287(3):L510-4.