beta-Transducin Repeat-Containing Proteins
"beta-Transducin Repeat-Containing Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
| Descriptor ID |
D044844
|
| MeSH Number(s) |
D12.776.157.169.500
|
| Concept/Terms |
beta-Transducin Repeat-Containing Proteins- beta-Transducin Repeat-Containing Proteins
- Repeat-Containing Proteins, beta-Transducin
- beta Transducin Repeat Containing Proteins
- beta-Transducin Repeat-Containing Protein
- Protein, beta-Transducin Repeat-Containing
- Repeat-Containing Protein, beta-Transducin
- beta Transducin Repeat Containing Protein
- beta-TrCP
- beta TrCP
- betaTrCP
|
Below are MeSH descriptors whose meaning is more general than "beta-Transducin Repeat-Containing Proteins".
Below are MeSH descriptors whose meaning is more specific than "beta-Transducin Repeat-Containing Proteins".
This graph shows the total number of publications written about "beta-Transducin Repeat-Containing Proteins" by people in this website by year, and whether "beta-Transducin Repeat-Containing Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta-Transducin Repeat-Containing Proteins" by people in Profiles.
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Lau AW, Fukushima H, Wei W. The Fbw7 and betaTRCP E3 ubiquitin ligases and their roles in tumorigenesis. Front Biosci (Landmark Ed). 2012 06 01; 17(6):2197-212.
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Elcheva I, Goswami S, Noubissi FK, Spiegelman VS. CRD-BP protects the coding region of betaTrCP1 mRNA from miR-183-mediated degradation. Mol Cell. 2009 Jul 31; 35(2):240-6.
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Noubissi FK, Elcheva I, Bhatia N, Shakoori A, Ougolkov A, Liu J, Minamoto T, Ross J, Fuchs SY, Spiegelman VS. CRD-BP mediates stabilization of betaTrCP1 and c-myc mRNA in response to beta-catenin signalling. Nature. 2006 Jun 15; 441(7095):898-901.