Phosphatidylinositol Diacylglycerol-Lyase
"Phosphatidylinositol Diacylglycerol-Lyase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.
| Descriptor ID |
D043265
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| MeSH Number(s) |
D08.811.277.352.640.700.700.500 D08.811.520.650.800
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| Concept/Terms |
Phosphatidylinositol Diacylglycerol-Lyase- Phosphatidylinositol Diacylglycerol-Lyase
- Diacylglycerol-Lyase, Phosphatidylinositol
- Phosphatidylinositol Diacylglycerol Lyase
- Monophosphatidylinositol Phosphodiesterase
- Phosphodiesterase, Monophosphatidylinositol
- 1-Phosphatidylinositol Phosphodiesterase
- 1 Phosphatidylinositol Phosphodiesterase
- Phosphodiesterase, 1-Phosphatidylinositol
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Below are MeSH descriptors whose meaning is more general than "Phosphatidylinositol Diacylglycerol-Lyase".
Below are MeSH descriptors whose meaning is more specific than "Phosphatidylinositol Diacylglycerol-Lyase".
This graph shows the total number of publications written about "Phosphatidylinositol Diacylglycerol-Lyase" by people in this website by year, and whether "Phosphatidylinositol Diacylglycerol-Lyase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphatidylinositol Diacylglycerol-Lyase" by people in Profiles.
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Gruszynski AE, van Deursen FJ, Albareda MC, Best A, Chaudhary K, Cliffe LJ, del Rio L, Dunn JD, Ellis L, Evans KJ, Figueiredo JM, Malmquist NA, Omosun Y, Palenchar JB, Prickett S, Punkosdy GA, van Dooren G, Wang Q, Menon AK, Matthews KR, Bangs JD. Regulation of surface coat exchange by differentiating African trypanosomes. Mol Biochem Parasitol. 2006 Jun; 147(2):211-23.
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Rios JC, Melendez-Vasquez CV, Einheber S, Lustig M, Grumet M, Hemperly J, Peles E, Salzer JL. Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination. J Neurosci. 2000 Nov 15; 20(22):8354-64.
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Shimohama S, Fujimoto S, Tresser N, Richey P, Perry G, Whitehouse PJ, Homma Y, Takenawa T, Taniguchi T, Suenaga T, et al. Aberrant phosphoinositide metabolism in Alzheimer's disease. Ann N Y Acad Sci. 1993 Sep 24; 695:46-9.
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Das S, Traynor-Kaplan A, Reiner DS, Meng TC, Gillin FD. A surface antigen of Giardia lamblia with a glycosylphosphatidylinositol anchor. J Biol Chem. 1991 Nov 05; 266(31):21318-25.