Pick Disease of the Brain
"Pick Disease of the Brain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)
| Descriptor ID |
D020774
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| MeSH Number(s) |
C10.228.140.380.266.299.500 F03.615.400.380.299.500
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| Concept/Terms |
Pick Disease of the Brain- Pick Disease of the Brain
- Brain Atrophy, Circumscribed Lobar
- Pick Disease
- Disease, Pick
- Picks Disease of Brain
- Lobar Atrophy Of Brain
- Pick's Disease
- Disease, Pick's
- Picks Disease
- Lobar Atrophy of the Brain
- Dementia with Lobar Atrophy and Neuronal Cytoplasmic Inclusions
- Pick Disease Of Brain
- Lobar Atrophy (Brain)
- Atrophies, Lobar (Brain)
- Atrophy, Lobar (Brain)
- Lobar Atrophies (Brain)
- Circumscribed Lobar Atrophy of the Brain
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Below are MeSH descriptors whose meaning is more general than "Pick Disease of the Brain".
Below are MeSH descriptors whose meaning is more specific than "Pick Disease of the Brain".
This graph shows the total number of publications written about "Pick Disease of the Brain" by people in this website by year, and whether "Pick Disease of the Brain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
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Below are the most recent publications written about "Pick Disease of the Brain" by people in Profiles.
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Mondrag?n-Rodr?guez S, Mena R, Binder LI, Smith MA, Perry G, Garc?a-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathol Appl Neurobiol. 2008 Feb; 34(1):62-75.
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Laurin D, Masaki KH, White LR, Launer LJ. Ankle-to-brachial index and dementia: the Honolulu-Asia Aging Study. Circulation. 2007 Nov 13; 116(20):2269-74.
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Lee HG, Ueda M, Miyamoto Y, Yoneda Y, Perry G, Smith MA, Zhu X. Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease. Brain Res. 2006 Dec 08; 1124(1):1-4.
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Hartzler AW, Zhu X, Siedlak SL, Castellani RJ, Avil? J, Perry G, Smith MA. The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau. Neurobiol Aging. 2002 Sep-Oct; 23(5):855-9.