Human Growth Hormone

"Human Growth Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 191-amino acid polypeptide hormone secreted by the human adenohypophysis (PITUITARY GLAND, ANTERIOR), also known as GH or somatotropin. Synthetic growth hormone, termed somatropin, has replaced the natural form in therapeutic usage such as treatment of dwarfism in children with growth hormone deficiency.

Descriptor ID	D019382
MeSH Number(s)	D06.472.699.631.525.425.875 D12.644.548.691.525.425.875
Concept/Terms	Human Growth Hormone Human Growth Hormone Growth Hormone, Human hGH (Human Growth Hormone) Somatropin (Human) Somatotropin (Human) Somatropin Serostim Serostim Zomacton Zomacton Cryo-Tropin Cryo-Tropin Cryo Tropin CryoTropin Recombinant Human Growth Hormone (Mammalian) Recombinant Human Growth Hormone (Mammalian) r-hGH-M r-hGH(m) Humatrope Humatrope Umatrope Maxomat Maxomat Norditropin Norditropin Norditropin Simplexx Norditropine Nutropin Nutropin Omnitrope Omnitrope Saizen Saizen Genotropin Genotropin Genotonorm

Below are MeSH descriptors whose meaning is more general than "Human Growth Hormone".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Pituitary Hormones [D06.472.699.631]
Pituitary Hormones, Anterior [D06.472.699.631.525]
Growth Hormone [D06.472.699.631.525.425]
Human Growth Hormone [D06.472.699.631.525.425.875]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Hormones [D12.644.548]
Pituitary Hormones [D12.644.548.691]
Pituitary Hormones, Anterior [D12.644.548.691.525]
Growth Hormone [D12.644.548.691.525.425]
Human Growth Hormone [D12.644.548.691.525.425.875]

Below are MeSH descriptors whose meaning is related to "Human Growth Hormone".

Below are MeSH descriptors whose meaning is more specific than "Human Growth Hormone".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Human Growth Hormone" by people in this website by year, and whether "Human Growth Hormone" was a major or minor topic of these publications.

Bar chart showing 15 publications over 10 distinct years, with a maximum of 3 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	1	2
1998	2	0	2
2003	1	0	1
2004	2	1	3
2005	2	0	2
2007	1	0	1
2008	1	0	1
2009	1	0	1
2010	1	0	1
2019	0	1	1

Below are the most recent publications written about "Human Growth Hormone" by people in Profiles.

van Iersel L, Li Z, Srivastava DK, Brinkman TM, Bjornard KL, Wilson CL, Green DM, Merchant TE, Pui CH, Howell RM, Smith SA, Armstrong GT, Hudson MM, Robison LL, Ness KK, Gajjar A, Krull KR, Sklar CA, van Santen HM, Chemaitilly W. Hypothalamic-Pituitary Disorders in Childhood Cancer Survivors: Prevalence, Risk Factors and Long-Term Health Outcomes. J Clin Endocrinol Metab. 2019 12 01; 104(12):6101-6115.

View in: PubMed
Bustamante JJ, Grigorian AL, Mu?oz J, Aguilar RM, Trevi?o LR, Martinez AO, Haro LS. Human growth hormone: 45-kDa isoform with extraordinarily stable interchain disulfide links has attenuated receptor-binding and cell-proliferative activities. Growth Horm IGF Res. 2010 Aug; 20(4):298-304.

View in: PubMed
Bustamante JJ, Gonzalez L, Carroll CA, Weintraub ST, Aguilar RM, Mu?oz J, Martinez AO, Haro LS. O-Glycosylated 24 kDa human growth hormone has a mucin-like biantennary disialylated tetrasaccharide attached at Thr-60. Proteomics. 2009 Jul; 9(13):3474-88.

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Yuen KC, Cook DM, Sahasranam P, Patel P, Ghods DE, Shahinian HK, Friedman TC. Prevalence of GH and other anterior pituitary hormone deficiencies in adults with nonsecreting pituitary microadenomas and normal serum IGF-1 levels. Clin Endocrinol (Oxf). 2008 Aug; 69(2):292-8.

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Grigorian AL, Bustamante JJ, Mu?oz J, Aguilar RM, Martinez AO, Haro LS. Preparative alkaline urea gradient PAGE: application to purification of extraordinarily-stable disulfide-linked homodimer of human growth hormone. Electrophoresis. 2007 Nov; 28(21):3829-36.

View in: PubMed
Bustamante JJ, Garcia M, Gonzalez L, Garcia J, Flores R, Aguilar RM, Trevino A, Benavides L, Martinez AO, Haro LS. Separation of proteins with a molecular mass difference of 2 kDa utilizing preparative double-inverted gradient polyacrylamide gel electrophoresis under nonreducing conditions: application to the isolation of 24 kDa human growth hormone. Electrophoresis. 2005 Dec; 26(23):4389-95.

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Grigorian AL, Bustamante JJ, Hernandez P, Martinez AO, Haro LS. Extraordinarily stable disulfide-linked homodimer of human growth hormone. Protein Sci. 2005 Apr; 14(4):902-13.

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Dixit VD, Schaffer EM, Pyle RS, Collins GD, Sakthivel SK, Palaniappan R, Lillard JW, Taub DD. Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J Clin Invest. 2004 Jul; 114(1):57-66.

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Nunlee-Bland G, Rana SR, Houston-Yu PE, Odonkor W. Growth hormone deficiency in patients with sickle cell disease and growth failure. J Pediatr Endocrinol Metab. 2004 Apr; 17(4):601-6.

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Friedman TC, Shahinian H. Bilateral cerebral aneurysms impinging on the pituitary. Pituitary. 2004; 7(3):193-194.

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