Receptors, Somatotropin

"Receptors, Somatotropin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell surface proteins that bind GROWTH HORMONE with high affinity and trigger intracellular changes influencing the behavior of cells. Activation of growth hormone receptors regulates amino acid transport through cell membranes, RNA translation to protein, DNA transcription, and protein and amino acid catabolism in many cell types. Many of these effects are mediated indirectly through stimulation of the release of somatomedins.

Descriptor ID	D011986
MeSH Number(s)	D12.776.543.750.750.555.770 D12.776.543.750.750.660.750
Concept/Terms	Receptors, Somatotropin Receptors, Somatotropin Receptor, Growth Hormone Somatotropin Receptors Receptors, Growth Hormone Somatotropin Receptor Growth Hormone Receptor Hormone Receptor, Growth Growth Hormone Receptors Hormone Receptors, Growth Receptors, Somatomammotropin Receptors, Somatomammotropin Somatomammotropin Receptors Somatomammotropin Receptor

Below are MeSH descriptors whose meaning is more general than "Receptors, Somatotropin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Neuropeptide [D12.776.543.750.750.555]
Receptors, Somatotropin [D12.776.543.750.750.555.770]
Receptors, Pituitary Hormone [D12.776.543.750.750.660]
Receptors, Somatotropin [D12.776.543.750.750.660.750]

Below are MeSH descriptors whose meaning is related to "Receptors, Somatotropin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Somatotropin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Somatotropin" by people in this website by year, and whether "Receptors, Somatotropin" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1999	1	0	1
2003	0	1	1
2009	1	0	1
2012	0	1	1
2013	1	0	1
2017	0	1	1
2018	0	1	1
2021	1	0	1
2024	1	1	2

Below are the most recent publications written about "Receptors, Somatotropin" by people in Profiles.

Poudel SB, Ruff RR, He Z, Dixit M, Yildirim G, Jayarathne H, Manchanayake DH, Basta-Pljakic J, Duran-Ortiz S, Schaffler MB, Kopchick JJ, Sadagurski M, Yakar S. The impact of inactivation of the GH/IGF axis during aging on healthspan. Geroscience. 2025 Jun; 47(3):3027-3042.

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Chen R, Donlon TA, Morris BJ, Allsopp RC, Willcox BJ, Masaki KH. Association of alcohol with lung cancer risk in men with different growth hormone receptor genotypes. Lung Cancer. 2024 Dec; 198:107971.

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Donlon TA, Chen R, Masaki KH, Willcox DC, Allsopp RC, Willcox BJ, Morris BJ. Association of growth hormone receptor gene variant with longevity in men is due to amelioration of increased mortality risk from hypertension. Aging (Albany NY). 2021 06 01; 13(11):14745-14767.

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P?rez-Ibave DC, Rodr?guez-S?nchez IP, Garza-Rodr?guez ML, P?rez-Maya AA, Luna M, Ar?mburo C, Tsin A, Perry G, Mohamed-Noriega K, Mohamed-Noriega J, Cavazos-Adame H, Mohamed-Hamsho J, Barrera-Salda?a HA. Expression of growth hormone gene in the baboon eye. Exp Eye Res. 2018 04; 169:157-169.

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Liu Z, Han T, Werner H, Rosen CJ, Schaffler MB, Yakar S. Reduced Serum IGF-1 Associated With Hepatic Osteodystrophy Is a Main Determinant of Low Cortical but Not Trabecular Bone Mass. J Bone Miner Res. 2018 01; 33(1):123-136.

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Wu Y, Sun H, Basta-Pljakic J, Cardoso L, Kennedy OD, Jasper H, Domen? H, Karabatas L, Guida C, Schaffler MB, Rosen CJ, Yakar S. Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor. J Bone Miner Res. 2013 Jul; 28(7):1575-86.

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Blackmore DG, Reynolds BA, Golmohammadi MG, Large B, Aguilar RM, Haro L, Waters MJ, Rietze RL. Growth hormone responsive neural precursor cells reside within the adult mammalian brain. Sci Rep. 2012; 2:250.

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Aguilar RM, Talamantes FJ, Bustamante JJ, Mu?oz J, Trevi?o LR, Martinez AO, Haro LS. MAP dendrimer elicits antibodies for detecting rat and mouse GH-binding proteins. J Pept Sci. 2009 Feb; 15(2):78-88.

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Liu W, Thomas SG, Asa SL, Gonzalez-Cadavid N, Bhasin S, Ezzat S. Myostatin is a skeletal muscle target of growth hormone anabolic action. J Clin Endocrinol Metab. 2003 Nov; 88(11):5490-6.

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Haro LS, Bustamante J, Hernandez P, Flores R, Aguilar R, Lopez-Guajardo C, Martinez AO. Biochemistry and pharmacology of rabbit cardiac growth hormone (GH) receptors. Mol Cell Endocrinol. 1999 Jun 25; 152(1-2):179-87.

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