12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
"12-Hydroxy-5,8,10,14-eicosatetraenoic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)
| Descriptor ID |
D019377
|
| MeSH Number(s) |
D10.251.355.255.100.300.425 D10.251.355.310.166.550.425
|
| Concept/Terms |
12-S-HETE- 12-S-HETE
- 12-S-Hydroxyeicosatetraenoic Acid
- 12 S Hydroxyeicosatetraenoic Acid
- Acid, 12-S-Hydroxyeicosatetraenoic
|
Below are MeSH descriptors whose meaning is more general than "12-Hydroxy-5,8,10,14-eicosatetraenoic Acid".
Below are MeSH descriptors whose meaning is more specific than "12-Hydroxy-5,8,10,14-eicosatetraenoic Acid".
This graph shows the total number of publications written about "12-Hydroxy-5,8,10,14-eicosatetraenoic Acid" by people in this website by year, and whether "12-Hydroxy-5,8,10,14-eicosatetraenoic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "12-Hydroxy-5,8,10,14-eicosatetraenoic Acid" by people in Profiles.
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Chen X, Li N, Wang S, Hong J, Fang M, Yousselfson J, Yang P, Newman RA, Lubet RA, Yang CS. Aberrant arachidonic acid metabolism in esophageal adenocarcinogenesis, and the effects of sulindac, nordihydroguaiaretic acid, and alpha-difluoromethylornithine on tumorigenesis in a rat surgical model. Carcinogenesis. 2002 Dec; 23(12):2095-102.