"Pyruvic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
| Descriptor ID |
D019289
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| MeSH Number(s) |
D02.241.755.812.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyruvic Acid".
Below are MeSH descriptors whose meaning is more specific than "Pyruvic Acid".
This graph shows the total number of publications written about "Pyruvic Acid" by people in this website by year, and whether "Pyruvic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyruvic Acid" by people in Profiles.
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Shimada BK, Boyman L, Huang W, Zhu J, Yang Y, Chen F, Kane MA, Yadava N, Zou L, Lederer WJ, Polster BM, Chao W. Pyruvate-Driven Oxidative Phosphorylation is Downregulated in Sepsis-Induced Cardiomyopathy: A Study of Mitochondrial Proteome. Shock. 2022 04 01; 57(4):553-564.
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Xu L, Phelix CF, Chen LY. Structural Insights into the Human Mitochondrial Pyruvate Carrier Complexes. J Chem Inf Model. 2021 11 22; 61(11):5614-5625.
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Sukonina V, Ma H, Zhang W, Bartesaghi S, Subhash S, Heglind M, Foyn H, Betz MJ, Nilsson D, Lidell ME, Naumann J, Haufs-Brusberg S, Palmgren H, Mondal T, Beg M, Jedrychowski MP, Task?n K, Pfeifer A, Peng XR, Kanduri C, Enerb?ck S. FOXK1 and FOXK2 regulate aerobic glycolysis. Nature. 2019 02; 566(7743):279-283.
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Sanders S, Vierling RJ, Bartee D, DeColli AA, Harrison MJ, Aklinski JL, Koppisch AT, Freel Meyers CL. Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-d-xylulose 5-Phosphate Synthase. ACS Infect Dis. 2017 07 14; 3(7):467-478.
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Ryans K, Omosun Y, McKeithen DN, Simoneaux T, Mills CC, Bowen N, Eko FO, Black CM, Igietseme JU, He Q. The immunoregulatory role of alpha enolase in dendritic cell function during Chlamydia infection. BMC Immunol. 2017 05 19; 18(1):27.
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Stoisser T, Brunsteiner M, Wilson DK, Nidetzky B. Conformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr(215) in Aerococcus viridans lactate oxidase. Sci Rep. 2016 06 15; 6:27892.
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Korte-Berwanger M, Sakinc T, Kline K, Nielsen HV, Hultgren S, Gatermann SG. Significance of the D-serine-deaminase and D-serine metabolism of Staphylococcus saprophyticus for virulence. Infect Immun. 2013 Dec; 81(12):4525-33.
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Negi VS, Bingham JP, Li QX, Borthakur D. midD-encoded 'rhizomimosinase' from Rhizobium sp. strain TAL1145 is a C-N lyase that catabolizes L-mimosine into 3-hydroxy-4-pyridone, pyruvate and ammonia. Amino Acids. 2013 Jun; 44(6):1537-47.
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McDermott JR, Rosen BP, Liu Z. Jen1p: a high affinity selenite transporter in yeast. Mol Biol Cell. 2010 Nov 15; 21(22):3934-41.
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Awaya JD, Tittabutr P, Li QX, Borthakur D. Pyruvate carboxylase is involved in metabolism of mimosine by Rhizobium sp. strain TAL1145. Arch Microbiol. 2008 Oct; 190(4):409-15.