Matrix Metalloproteinase 3

"Matrix Metalloproteinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An extracellular endopeptidase of vertebrate tissues similar to MATRIX METALLOPROTEINASE 1. It digests PROTEOGLYCAN; FIBRONECTIN; COLLAGEN types III, IV, V, and IX, and activates procollagenase. (Enzyme Nomenclature, 1992)

Descriptor ID	D019278
MeSH Number(s)	D08.811.277.656.300.480.525.700.200 D08.811.277.656.675.374.525.700.200 D12.644.276.848.200 D12.776.467.836.200
Concept/Terms	Matrix Metalloproteinase 3 Matrix Metalloproteinase 3 Metalloproteinase 3, Matrix Transin MMP3 Metalloproteinase Metalloproteinase, MMP3 Stromelysin 1 MMP-3 Metalloproteinase MMP 3 Metalloproteinase Metalloproteinase, MMP-3 Stromelysin

Below are MeSH descriptors whose meaning is more general than "Matrix Metalloproteinase 3".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Endopeptidases [D08.811.277.656.300]
Metalloendopeptidases [D08.811.277.656.300.480]
Matrix Metalloproteinases [D08.811.277.656.300.480.525]
Matrix Metalloproteinases, Secreted [D08.811.277.656.300.480.525.700]
Matrix Metalloproteinase 3 [D08.811.277.656.300.480.525.700.200]
Metalloproteases [D08.811.277.656.675]
Metalloendopeptidases [D08.811.277.656.675.374]
Matrix Metalloproteinases [D08.811.277.656.675.374.525]
Matrix Metalloproteinases, Secreted [D08.811.277.656.675.374.525.700]
Matrix Metalloproteinase 3 [D08.811.277.656.675.374.525.700.200]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Matrix Metalloproteinases, Secreted [D12.644.276.848]
Matrix Metalloproteinase 3 [D12.644.276.848.200]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Matrix Metalloproteinases, Secreted [D12.776.467.836]
Matrix Metalloproteinase 3 [D12.776.467.836.200]

Below are MeSH descriptors whose meaning is related to "Matrix Metalloproteinase 3".

Below are MeSH descriptors whose meaning is more specific than "Matrix Metalloproteinase 3".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Matrix Metalloproteinase 3" by people in this website by year, and whether "Matrix Metalloproteinase 3" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2002 and 2004 and 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	2	0	2
2004	0	2	2
2010	1	0	1
2011	0	1	1
2012	1	1	2
2013	1	0	1
2016	0	1	1
2025	1	0	1

Below are the most recent publications written about "Matrix Metalloproteinase 3" by people in Profiles.

Rivera-Serrano M, Flores-Col?n M, Valiyeva F, Mel?ndez LM, Vivas-Mej?a PE. Upregulation of MMP3 Promotes Cisplatin Resistance in Ovarian Cancer. Int J Mol Sci. 2025 Apr 24; 26(9).

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Rhee do Y, Cho HI, Park GH, Moon HR, Chang SE, Won CH, Jung JM, Park KY, Lee MW, Choi JH, Moon KC, Lee DC, Goo B. Histological and molecular analysis of the long-pulse 1,064-nm Nd:YAG laser irradiation on the ultraviolet-damaged skin of hairless mice: In association with pulse duration change. J Cosmet Laser Ther. 2016; 18(1):16-21.

View in: PubMed
Liu M, Wilson NO, Hibbert JM, Stiles JK. STAT3 regulates MMP3 in heme-induced endothelial cell apoptosis. PLoS One. 2013; 8(8):e71366.

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Kim Y, Ollberding NJ, Shvetsov YB, Franke AA, Wilkens LR, Maskarinec G, Hernandez BY, Le Marchand L, Henderson BE, Kolonel LN, Goodman MT. Plasma matrix metalloproteinases and postmenopausal breast cancer risk: a nested case-control study in the Multiethnic Cohort study. Breast Cancer Res Treat. 2012 Dec; 136(3):837-45.

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Roe K, Kumar M, Lum S, Orillo B, Nerurkar VR, Verma S. West Nile virus-induced disruption of the blood-brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases. J Gen Virol. 2012 Jun; 93(Pt 6):1193-1203.

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Sirad F, Hlaing S, Kovanecz I, Artaza JN, Garcia LA, Rajfer J, Ferrini MG. Sildenafil promotes smooth muscle preservation and ameliorates fibrosis through modulation of extracellular matrix and tissue growth factor gene expression after bilateral cavernosal nerve resection in the rat. J Sex Med. 2011 Apr; 8(4):1048-60.

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Leong DJ, Gu XI, Li Y, Lee JY, Laudier DM, Majeska RJ, Schaffler MB, Cardoso L, Sun HB. Matrix metalloproteinase-3 in articular cartilage is upregulated by joint immobilization and suppressed by passive joint motion. Matrix Biol. 2010 Jun; 29(5):420-6.

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McColgan P, Peck GE, Greenhalgh RM, Sharma P. The genetics of abdominal aortic aneurysms: a comprehensive meta-analysis involving eight candidate genes in over 16,700 patients. Int Surg. 2009 Oct-Dec; 94(4):350-8.

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McColgan P, Sharma P. Polymorphisms of matrix metalloproteinases 1, 2, 3 and 9 and susceptibility to lung, breast and colorectal cancer in over 30,000 subjects. Int J Cancer. 2009 Sep 15; 125(6):1473-8.

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Tang J, Liu J, Zhou C, Alexander JS, Nanda A, Granger DN, Zhang JH. Mmp-9 deficiency enhances collagenase-induced intracerebral hemorrhage and brain injury in mutant mice. J Cereb Blood Flow Metab. 2004 Oct; 24(10):1133-45.

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