"Receptors, Purinergic P1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of cell surface receptors that prefer ADENOSINE to other endogenous PURINES. Purinergic P1 receptors are widespread in the body including the cardiovascular, respiratory, immune, and nervous systems. There are at least two pharmacologically distinguishable types (A1 and A2, or Ri and Ra).
| Descriptor ID |
D018047
|
| MeSH Number(s) |
D12.776.543.750.695.700.700 D12.776.543.750.720.700.700
|
| Concept/Terms |
Receptors, Purinergic P1- Receptors, Purinergic P1
- Adenosine Receptors
- Receptors, Adenosine
- P1 Purinoceptors
- Purinoceptors, P1
- Receptor, Purinergic P1
- P1 Receptor, Purinergic
- Purinergic P1 Receptor
- Purinergic P1 Receptors
- P1 Receptors, Purinergic
- Adenosine Receptor
- Receptor, Adenosine
- P1 Purinoceptor
- Purinoceptor, P1
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P1".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P1".
This graph shows the total number of publications written about "Receptors, Purinergic P1" by people in this website by year, and whether "Receptors, Purinergic P1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Purinergic P1" by people in Profiles.
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Samanta PN, Kar S, Leszczynski J. Recent Advances of In-Silico Modeling of Potent Antagonists for the Adenosine Receptors. Curr Pharm Des. 2019; 25(7):750-773.
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Mateo Z, Porter JT. Developmental decline in modulation of glutamatergic synapses in layer IV of the barrel cortex by group II metabotropic glutamate receptors. Neuroscience. 2015 Apr 02; 290:41-8.
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Rizvi YQ, Mehta CS, Oyekan A. Interactions of PPAR-alpha and adenosine receptors in hypoxia-induced angiogenesis. Vascul Pharmacol. 2013 Nov-Dec; 59(5-6):144-51.
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Xia Y, Javadov S, Gan TX, Pang T, Cook MA, Karmazyn M. Distinct KATP channels mediate the antihypertrophic effects of adenosine receptor activation in neonatal rat ventricular myocytes. J Pharmacol Exp Ther. 2007 Jan; 320(1):14-21.
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Murphy K, Gerzanich V, Zhou H, Ivanova S, Dong Y, Hoffman G, West GA, Winn HR, Simard JM. Adenosine-A2a receptor down-regulates cerebral smooth muscle L-type Ca2+ channel activity via protein tyrosine phosphatase, not cAMP-dependent protein kinase. Mol Pharmacol. 2003 Sep; 64(3):640-9.
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Heinbockel T, Pape HC. Modulatory effects of adenosine on inhibitory postsynaptic potentials in the lateral amygdala of the rat. Br J Pharmacol. 1999 Sep; 128(1):190-6.
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Porter JT, McCarthy KD. Adenosine receptors modulate [Ca2+]i in hippocampal astrocytes in situ. J Neurochem. 1995 Oct; 65(4):1515-23.