Lignans

"Lignans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)

Descriptor ID	D017705
MeSH Number(s)	D02.455.426.559.389.140.450
Concept/Terms	Lignans Lignans Neolignans Neolignans

Below are MeSH descriptors whose meaning is more general than "Lignans".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Hydrocarbons [D02.455]
Hydrocarbons, Cyclic [D02.455.426]
Hydrocarbons, Aromatic [D02.455.426.559]
Benzene Derivatives [D02.455.426.559.389]
Benzyl Compounds [D02.455.426.559.389.140]
Lignans [D02.455.426.559.389.140.450]

Below are MeSH descriptors whose meaning is related to "Lignans".

Below are MeSH descriptors whose meaning is more specific than "Lignans".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lignans" by people in this website by year, and whether "Lignans" was a major or minor topic of these publications.

Bar chart showing 16 publications over 13 distinct years, with a maximum of 3 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
2002	0	1	1
2006	1	0	1
2008	1	0	1
2013	1	0	1
2014	3	0	3
2015	1	0	1
2017	0	1	1
2019	1	0	1
2020	1	0	1
2021	1	0	1
2022	2	0	2
2024	1	0	1

Below are the most recent publications written about "Lignans" by people in Profiles.

Hao Q, Henning SM, Magyar CE, Said J, Zhong J, Rettig MB, Vadgama JV, Wang P. Enhanced Chemoprevention of Prostate Cancer by Combining Arctigenin with Green Tea and Quercetin in Prostate-Specific Phosphatase and Tensin Homolog Knockout Mice. Biomolecules. 2024 Jan 14; 14(1).

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Liu F, Mallick S, O'Donnell TJ, Rouzimaimaiti R, Luo Y, Sun R, Wall M, Wongwiwatthananukit S, Date A, Silva DK, Williams PG, Chang LC. Coumarinolignans with Reactive Oxygen Species (ROS) and NF-?B Inhibitory Activities from the Roots of Waltheria indica. Molecules. 2022 May 19; 27(10).

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Li M, Cai Q, Gao YT, Franke AA, Zhang X, Zhao Y, Wen W, Lan Q, Rothman N, Shyr Y, Shu XO, Zheng W, Yang G. Phytoestrogens and lung cancer risk: a nested case-control study in never-smoking Chinese women. Am J Clin Nutr. 2022 03 04; 115(3):643-651.

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Liu G, Li J, Li Y, Hu Y, Franke AA, Liang L, Hu FB, Chan AT, Mukamal KJ, Rimm EB, Sun Q. Gut microbiota-derived metabolites and risk of coronary artery disease: a prospective study among US men and women. Am J Clin Nutr. 2021 07 01; 114(1):238-247.

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Hao Q, Diaz T, Verduzco ADR, Magyar CE, Zhong J, Elshimali Y, Rettig MB, Henning SM, Vadgama JV, Wang P. Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor. Sci Rep. 2020 Jan 29; 10(1):1403.

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Bess EN, Bisanz JE, Yarza F, Bustion A, Rich BE, Li X, Kitamura S, Waligurski E, Ang QY, Alba DL, Spanogiannopoulos P, Nayfach S, Koliwad SK, Wolan DW, Franke AA, Turnbaugh PJ. Genetic basis for the cooperative bioactivation of plant lignans by Eggerthella lenta and other human gut bacteria. Nat Microbiol. 2020 01; 5(1):56-66.

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Amawi H, Ashby CR, Samuel T, Peraman R, Tiwari AK. Polyphenolic Nutrients in Cancer Chemoprevention and Metastasis: Role of the Epithelial-to-Mesenchymal (EMT) Pathway. Nutrients. 2017 Aug 21; 9(8).

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Hu Y, Song Y, Franke AA, Hu FB, van Dam RM, Sun Q. A Prospective Investigation of the Association Between Urinary Excretion of Dietary Lignan Metabolites and Weight Change in US Women. Am J Epidemiol. 2015 Sep 15; 182(6):503-11.

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Wang P, Phan T, Gordon D, Chung S, Henning SM, Vadgama JV. Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells. Mol Nutr Food Res. 2015 Feb; 59(2):250-61.

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Ogungbe IV, Crouch RA, Demeritte T. (-) Arctigenin and (+) pinoresinol are antagonists of the human thyroid hormone receptor ?. J Chem Inf Model. 2014 Nov 24; 54(11):3051-5.

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