Bone Remodeling

"Bone Remodeling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The continuous turnover of BONE MATRIX and mineral that involves first an increase in BONE RESORPTION (osteoclastic activity) and later, reactive BONE FORMATION (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium HOMEOSTASIS. An imbalance in the regulation of bone remodeling's two contrasting events, bone resorption and bone formation, results in many of the metabolic bone diseases, such as OSTEOPOROSIS.

Descriptor ID	D016723
MeSH Number(s)	G11.427.213 G16.762.150
Concept/Terms	Bone Remodeling Bone Remodeling Remodeling, Bone Bone Turnover Bone Turnovers Turnover, Bone Turnovers, Bone

Below are MeSH descriptors whose meaning is more general than "Bone Remodeling".

Biological Sciences [G]
Musculoskeletal and Neural Physiological Phenomena [G11]
Musculoskeletal Physiological Phenomena [G11.427]
Bone Remodeling [G11.427.213]
Biological Phenomena [G16]
Regeneration [G16.762]
Bone Remodeling [G16.762.150]

Below are MeSH descriptors whose meaning is more specific than "Bone Remodeling".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bone Remodeling" by people in this website by year, and whether "Bone Remodeling" was a major or minor topic of these publications.

Bar chart showing 22 publications over 15 distinct years, with a maximum of 2 publications in 2002 and 2003 and 2006 and 2007 and 2008 and 2010 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2002	1	1	2
2003	2	0	2
2005	0	1	1
2006	1	1	2
2007	0	2	2
2008	0	2	2
2009	0	1	1
2010	2	0	2
2011	0	1	1
2012	1	0	1
2016	1	1	2
2017	0	1	1
2020	0	1	1
2025	1	0	1

Below are the most recent publications written about "Bone Remodeling" by people in Profiles.

Gonz?lez-Ch?vez SA, Loya-Rivera M, Nair S, Prieto-Carrasco R, Chaparro-Barrera E, Ruizesparza-Hinojos DA, Roy S, Pacheco-Tena C. IL-33 links inflammation and bone remodeling in experimental spondyloarthritis and human joint biopsies. Cytokine. 2025 Dec; 196:157031.

View in: PubMed
McCutcheon S, Majeska RJ, Spray DC, Schaffler MB, Vazquez M. Apoptotic Osteocytes Induce RANKL Production in Bystanders via Purinergic Signaling and Activation of Pannexin Channels. J Bone Miner Res. 2020 05; 35(5):966-977.

View in: PubMed
Narayanan A, Khanchandani P, Borkar RM, Ambati CR, Roy A, Han X, Bhoskar RN, Ragampeta S, Gannon F, Mysorekar V, Karanam B, V SM, Sivaramakrishnan V. Avascular Necrosis of Femoral Head: A Metabolomic, Biophysical, Biochemical, Electron Microscopic and Histopathological Characterization. Sci Rep. 2017 09 06; 7(1):10721.

View in: PubMed
Kennedy OD, Lendhey M, Mauer P, Philip A, Basta-Pljakic J, Schaffler MB. Microdamage induced by in vivo Reference Point Indentation in mice is repaired by osteocyte-apoptosis mediated remodeling. Bone. 2017 02; 95:192-198.

View in: PubMed
Dolan EB, Tallon D, Cheung WY, Schaffler MB, Kennedy OD, McNamara LM. Thermally induced osteocyte damage initiates pro-osteoclastogenic gene expression in vivo. J R Soc Interface. 2016 06; 13(119).

View in: PubMed
Courtland HW, Kennedy OD, Wu Y, Gao Y, Sun H, Schaffler MB, Yakar S. Low levels of plasma IGF-1 inhibit intracortical bone remodeling during aging. Age (Dordr). 2013 Oct; 35(5):1691-703.

View in: PubMed
Dickinson A, Taylor A, Browne M. Implant-bone interface healing and adaptation in resurfacing hip replacement. Comput Methods Biomech Biomed Engin. 2012; 15(9):935-47.

View in: PubMed
Sun HB, Andarawis-Puri N, Li Y, Fung DT, Lee JY, Wang VM, Basta-Pljakic J, Leong DJ, Sereysky JB, Ros SJ, Klug RA, Braman J, Schaffler MB, Jepsen KJ, Flatow EL. Cycle-dependent matrix remodeling gene expression response in fatigue-loaded rat patellar tendons. J Orthop Res. 2010 Oct; 28(10):1380-6.

View in: PubMed
Winters-Stone KM, Schwartz A, Nail LM. A review of exercise interventions to improve bone health in adult cancer survivors. J Cancer Surviv. 2010 Sep; 4(3):187-201.

View in: PubMed
Cardoso L, Herman BC, Verborgt O, Laudier D, Majeska RJ, Schaffler MB. Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue. J Bone Miner Res. 2009 Apr; 24(4):597-605.

View in: PubMed

People

Explore

Similar Concepts

Top Journals