"HIV Long Terminal Repeat" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
| Descriptor ID |
D016325
|
| MeSH Number(s) |
G02.111.570.080.708.850.400 G05.360.080.708.850.400
|
| Concept/Terms |
HIV Long Terminal Repeat- HIV Long Terminal Repeat
- LTR, Human Immunodeficiency Virus
- Human Immunodeficiency Virus LTR
- Long Terminal Repeat, HIV
- Human Immunodeficiency Virus Long Terminal Repeat
Trans-Acting Responsive Region, HIV- Trans-Acting Responsive Region, HIV
- Trans Acting Responsive Region, HIV
- HIV Trans-Acting Responsive Region
- HIV Trans Acting Responsive Region
- Trans-Activation Responsive Element, HIV
- Trans Activation Responsive Element, HIV
- Trans-Activation Responsive Region, HIV
- Trans Activation Responsive Region, HIV
- TAR Element, HIV
- HIV TAR Element
- HIV TAR Elements
- TAR Elements, HIV
Sp1-Binding Site, HIV- Sp1-Binding Site, HIV
- Sp1 Binding Site, HIV
- HIV Sp1-Binding Site
- HIV Sp1 Binding Site
- HIV Sp1-Binding Sites
- Sp1-Binding Sites, HIV
|
Below are MeSH descriptors whose meaning is more general than "HIV Long Terminal Repeat".
Below are MeSH descriptors whose meaning is more specific than "HIV Long Terminal Repeat".
This graph shows the total number of publications written about "HIV Long Terminal Repeat" by people in this website by year, and whether "HIV Long Terminal Repeat" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "HIV Long Terminal Repeat" by people in Profiles.
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Alanazi A, Ivanov A, Kumari N, Lin X, Wang S, Kovalskyy D, Nekhai S. Targeting Tat-TAR RNA Interaction for HIV-1 Inhibition. Viruses. 2021 10 06; 13(10).
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Van Duyne R, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, Easley R, Klase Z, Nekhai S, Kehn-Hall K, Kashanchi F. Varying modulation of HIV-1 LTR activity by Baf complexes. J Mol Biol. 2011 Aug 19; 411(3):581-96.
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Epie N, Ammosova T, Turner W, Nekhai S. Inhibition of PP2A by LIS1 increases HIV-1 gene expression. Retrovirology. 2006 Oct 02; 3:65.
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Mandal D, Dash C, Le Grice SF, Prasad VR. Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function. Nucleic Acids Res. 2006; 34(10):2853-63.
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Ammosova T, Washington K, Debebe Z, Brady J, Nekhai S. Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription. Retrovirology. 2005 Jul 27; 2:47.
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Miles LR, Agresta BE, Khan MB, Tang S, Levin JG, Powell MD. Effect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity. J Virol. 2005 Jun; 79(11):6859-67.
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Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription. Biochem J. 2002 Jun 15; 364(Pt 3):649-57.
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Bharucha DC, Zhou M, Nekhai S, Brady JN, Shukla RR, Kumar A. A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat. Virology. 2002 Apr 25; 296(1):6-16.
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Nunnari G, Otero M, Dornadula G, Vanella M, Zhang H, Frank I, Pomerantz RJ. Residual HIV-1 disease in seminal cells of HIV-1-infected men on suppressive HAART: latency without on-going cellular infections. AIDS. 2002 Jan 04; 16(1):39-45.
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Gujuluva C, Burns AR, Pushkarsky T, Popik W, Berger O, Bukrinsky M, Graves MC, Fiala M. HIV-1 penetrates coronary artery endothelial cells by transcytosis. Mol Med. 2001 Mar; 7(3):169-76.