Dextran Sulfate

"Dextran Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.

Descriptor ID	D016264
MeSH Number(s)	D09.698.365.272.300
Concept/Terms	Dextran Sulfate Dextran Sulfate Sulfate, Dextran Dextran Sulfate Sodium Dextran Sulfate Sodium Sulfate Sodium, Dextran Sodium Dextran Sulfate Dextran Sulfate, Sodium Sulfate, Sodium Dextran

Below are MeSH descriptors whose meaning is more general than "Dextran Sulfate".

Chemicals and Drugs [D]
Carbohydrates [D09]
Polysaccharides [D09.698]
Glucans [D09.698.365]
Dextrans [D09.698.365.272]
Dextran Sulfate [D09.698.365.272.300]

Below are MeSH descriptors whose meaning is related to "Dextran Sulfate".

Below are MeSH descriptors whose meaning is more specific than "Dextran Sulfate".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dextran Sulfate" by people in this website by year, and whether "Dextran Sulfate" was a major or minor topic of these publications.

Bar chart showing 14 publications over 10 distinct years, with a maximum of 3 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2006	0	1	1
2007	0	1	1
2015	0	1	1
2016	1	2	3
2017	0	1	1
2021	1	1	2
2022	0	2	2
2024	1	0	1
2025	0	1	1

Below are the most recent publications written about "Dextran Sulfate" by people in Profiles.

Figueroa-Gispert MDM, Ramos-Lugo CM, Ocasio-Malav? C, Scott RP, Ahrendsen JT, Gomez-Samblas M, Osuna A, Dorta-Estremera SM, Espino AM. Fh15 Reduces Colonic Inflammation and Leukocyte Infiltration in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model. Cells. 2025 05 29; 14(11).

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Zhu HT, Luo J, Peng Y, Cheng XF, Wu SZ, Zhao YD, Chang L, Sun ZJ, Dong DL. Nitazoxanide protects against experimental ulcerative colitis through improving intestinal barrier and inhibiting inflammation. Chem Biol Interact. 2024 May 25; 395:111013.

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Mesas C, Mart?nez R, Doello K, Ortiz R, L?pez-Jurado M, Berm?dez F, Qui?onero F, Prados J, Porres JM, Melguizo C. In vivo antitumor activity of Euphorbia lathyris ethanol extract in colon cancer models. Biomed Pharmacother. 2022 May; 149:112883.

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Kotla NG, Singh R, Baby BV, Rasala S, Rasool J, Hynes SO, Martin D, Egan LJ, Vemula PK, Jala VR, Rochev Y, Pandit A. Inflammation-specific targeted carriers for local drug delivery to inflammatory bowel disease. Biomaterials. 2022 02; 281:121364.

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Singh G, Haileselassie Y, Ji AR, Maecker HT, Sinha SR, Brim H, Habtezion A, Ashktorab H. Protective Effect of Saffron in Mouse Colitis Models Through Immune Modulation. Dig Dis Sci. 2022 07; 67(7):2922-2935.

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Banskota S, Brim H, Kwon YH, Singh G, Sinha SR, Wang H, Khan WI, Ashktorab H. Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice. Molecules. 2021 Jun 02; 26(11).

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Parnell EA, Walch EM, Lo DD. Inducible Colonic M Cells Are Dependent on TNFR2 but Not Lt?r, Identifying Distinct Signalling Requirements for Constitutive Versus Inducible M Cells. J Crohns Colitis. 2017 Jun 01; 11(6):751-760.

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Zhu C, Ling Q, Cai Z, Wang Y, Zhang Y, Hoffmann PR, Zheng W, Zhou T, Huang Z. Selenium-Containing Phycocyanin from Se-Enriched Spirulina platensis Reduces Inflammation in Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-?B Activation. J Agric Food Chem. 2016 Jun 22; 64(24):5060-70.

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Shukla PK, Chaudhry KK, Mir H, Gangwar R, Yadav N, Manda B, Meena AS, Rao R. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016 Mar 07; 16:189.

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Bennett KM, Parnell EA, Sanscartier C, Parks S, Chen G, Nair MG, Lo DD. Induction of Colonic M Cells during Intestinal Inflammation. Am J Pathol. 2016 05; 186(5):1166-79.

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