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Hassan Brim

TitleAssistant Professor
Faculty RankAssistant Professor
InstitutionHoward University
DepartmentPathology/ Cancer Center
Address2041 Georgia Avenue, NW
Suite 220, NW
Washington DC 20060
Phone2028064198
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    Research Interests: Genetics, Epigenetics and environmental factors in African American Colon Cancer

    Dr. Hassan Brim earned his PhD from the Free University of Brussels in the field of "Molecular Biology, Genetic Engineering and Environmental Microbiology." He then moved to the Naval Medical Center in Bethesda where he worked on the degradation and transformation of carcinogenic products in radioactive environments. This work was implemented in a radio resistant bacterium equipped with particular DNA repair mechanisms. This work has led to high profile publications in Nature Biotechnology and cited in Science Magazine. From there, Dr. Brim moved to study DNA repair in colon cancer specimens. He analyzed microsatellite instability, DNA methylation and chromosomal instability in colon cancer cases. He is currently addressing environmental factors that trigger and/or promote colon cancer among which the gut flora is a major player of which the role is yet to be defined. Dr. Brim is currently an Assistant professor at the Department of Pathology and has more than 30 publications.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Geng LN, Erlandson KM, Hornig M, Letts R, Selvaggi C, Ashktorab H, Atieh O, Bartram L, Brim H, Brosnahan SB, Brown J, Castro M, Charney A, Chen P, Deeks SG, Erdmann N, Flaherman VJ, Ghamloush MA, Goepfert P, Goldman JD, Han JE, Hess R, Hirshberg E, Hoover SE, Katz SD, Kelly JD, Klein JD, Krishnan JA, Lee-Iannotti J, Levitan EB, Marconi VC, Metz TD, Modes ME, Nikolich J?, Novak RM, Ofotokun I, Okumura MJ, Parthasarathy S, Patterson TF, Peluso MJ, Poppas A, Quintero Cardona O, Scott J, Shellito J, Sherif ZA, Singer NG, Taylor BS, Thaweethai T, Verduzco-Gutierrez M, Wisnivesky J, McComsey GA, Horwitz LI, Foulkes AS. 2024 Update of the RECOVER-Adult Long COVID Research Index. JAMA. 2024 Dec 18. PMID: 39693079.
      Citations:    Fields:    
    2. Brim H, Reddy CS, Chirumamilla L, Oskrochi G, Deverapalli M, Rashid R, Rashid M, Nair V, Morrison N, Byer D, Thompson T, Yasin B, Johnson D, Snowden A, Mammen P, Carter G, Jolly V, Thompson R, Abdulmoniem R, Karodeh N, Gojela Y, Ahmed A, Saroya S, Gibbs T, Dawodu D, Shayegh N, Ahmed AH, Zahedi I, Aduli F, Kibreab A, Laiyemo AO, Shokrani B, Zafar R, Nembhard C, Carethers JM, Ashktorab H. Trends and Symptoms Among Increasing Proportion of African Americans with Early-Onset Colorectal Cancer over a 60-Year Period. Dig Dis Sci. 2024 Nov 25. PMID: 39586927.
      Citations:    Fields:    
    3. Erlandson KM, Geng LN, Selvaggi CA, Thaweethai T, Chen P, Erdmann NB, Goldman JD, Henrich TJ, Hornig M, Karlson EW, Katz SD, Kim C, Cribbs SK, Laiyemo AO, Letts R, Lin JY, Marathe J, Parthasarathy S, Patterson TF, Taylor BD, Duffy ER, Haack M, Julg B, Maranga G, Hernandez C, Singer NG, Han J, Pemu P, Brim H, Ashktorab H, Charney AW, Wisnivesky J, Lin JJ, Chu HY, Go M, Singh U, Levitan EB, Goepfert PA, Nikolich J?, Hsu H, Peluso MJ, Kelly JD, Okumura MJ, Flaherman VJ, Quigley JG, Krishnan JA, Scholand MB, Hess R, Metz TD, Costantine MM, Rouse DJ, Taylor BS, Goldberg MP, Marshall GD, Wood J, Warren D, Horwitz L, Foulkes AS, McComsey GA. Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort. Ann Intern Med. 2024 Sep; 177(9):1209-1221. PMID: 39133923.
      Citations: 1     Fields:    Translation:HumansCells
    4. Ashktorab H, Oskrochi G, Challa SR, Chirumamilla LG, Ahangarzadeh F, Jones-Wonni B, Shayegh N, Rashid M, Naqvi Z, Ekpe E, Sabyasachi S, Zenebe A, Brim H. Correction to: High Prevalence of Diabetes Among Hospitalized COVID-19 Minority Patients: Data from a Single Tertiary Hospital. J Racial Ethn Health Disparities. 2024 Aug; 11(4):2517. PMID: 37552425.
      Citations:    Fields:    
    5. Rashid M, Rashid R, Saroya S, Deverapalli M, Brim H, Ashktorab H. Saffron as a Promising Therapy for Inflammatory Bowel Disease. Nutrients. 2024 Jul 20; 16(14). PMID: 39064796.
      Citations: 1     Fields:    Translation:HumansAnimals
    6. Aloufi A, Aubee J, Vargas KM, Apprey V, Thompson K, Copeland R, Kanaan Y, Ricks-Santi L, Brim H, Abbas M. Vitamin D receptor polymorphisms and associated miRNAs in the development of breast cancer in African American women. Gene. 2024 Nov 15; 927:148695. PMID: 38945313.
      Citations:    Fields:    Translation:HumansCells
    7. Ibecheozor C, Morales J, Ross J, Ezeofor A, McKie C, Scott VF, Kibreab A, Howell C, Aduli F, Brim H, Ashktorab H, Oyawusi M, McDonald-Pinkett S, Laiyemo AO. Nutritional Calorie Labeling and Menu Ordering Practices Among US Adults With Chronic Illnesses. Cureus. 2024 Apr; 16(4):e58484. PMID: 38765419.
      Citations:    
    8. Challa SR, Oskrochi G, Singh GP, Chirumamilla LG, Shayegh N, Nair VK, Littleton M, Byer DT, Morrison NA, Grossi BL, Ashanna B, Dusmatova S, Thompson T, Dawodu DO, Brim H, Ashktorab H. Predictors of mortality in hospitalized African American COVID-19 patients with cancer. Transl Cancer Res. 2024 Mar 31; 13(3):1314-1322. PMID: 38617523.
      Citations:    
    9. Ashktorab H, Pizuorno A, Chirumamilla LG, Adeleye F, Dalivand MM, Sherif ZA, Oskrochi G, Challa SR, Jones-Wonni B, Rankine S, Ekwunazu C, Banson A, Kim R, Gilliard C, Ekpe E, Shayegh N, Nyaunu C, Martins C, Slack A, Okwesili P, Abebe M, Batta Y, Ly D, Valarie O, Smith T, Watson K, Kolawole O, Tahmazian S, Atoba S, Khushbakht M, Riley G, Gavin W, Kara A, Hache-Marliere M, Palaiodimos L, Mani VR, Kalabin A, Gayam VR, Garlapati PR, Miller J, Jackson F, Carethers JM, Rustgi V, Brim H. African Americans Possessed High Prevalence of Comorbidities and Frequent Abdominal Symptoms, and Comprised A Disproportionate Share of Covid-19 Mortality among 9,873 Us- Hospitalized Patients Early in the Pandemic. Arch Intern Med Res. 2024; 7(1):27-41. PMID: 38694760.
      Citations:    
    10. Rashid M, Rashid R, Gadewal N, Carethers JM, Koi M, Brim H, Ashktorab H. High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer. Neoplasia. 2024 03; 49:100970. PMID: 38281411.
      Citations:    Fields:    Translation:HumansCells
    11. Khan M, Hearn K, Parry C, Rashid M, Brim H, Ashktorab H, Kwabi-Addo B. Mechanism of Antitumor Effects of Saffron in Human Prostate Cancer Cells. Nutrients. 2023 12 28; 16(1). PMID: 38201944.
      Citations: 2     Fields:    Translation:HumansAnimals
    12. Sherif ZA, Deverapalli M, Challa SR, Martirosyan Z, Whitesell P, Pizuorno AM, Naqvi Z, Tulloch IK, Oskrochi G, Brim H, Ashktorab H. Potential long-term neurological and gastrointestinal effects of COVID-19: A review of adult cohorts. World J Methodol. 2023 Sep 20; 13(4):323-336. PMID: 37771866.
      Citations:    
    13. Ashktorab H, Geramfard S, Rashid M, Rashid R, Mynedi SM, Nouraie M, Nezamloo A, Brim H. Exploring the Incidence and Associated Risk Factors of Barrett's Esophagus in African Americans: A Retrospective Study. Rep Glob Health Res. 2023; 6(3). PMID: 38044960.
      Citations:    
    14. Ashktorab H, Oskrochi G, Challa SR, Chirumamilla LG, Ahangarzadeh F, Jones-Wonni B, Shayegh N, Rashid M, Naqvi Z, Ekpe E, Sabyasachi S, Zenebe A, Brim H. High Prevalence of Diabetes Among Hospitalized COVID-19 Minority Patients: Data from a Single Tertiary Hospital. J Racial Ethn Health Disparities. 2024 Aug; 11(4):2488-2497. PMID: 37500830.
      Citations:    Fields:    Translation:Humans
    15. Singh G, Brim H, Haileselassie Y, Varma S, Habtezion A, Rashid M, Sinha SR, Ashktorab H. Microbiomic and Metabolomic Analyses Unveil the Protective Effect of Saffron in a Mouse Colitis Model. Curr Issues Mol Biol. 2023 Jun 30; 45(7):5558-5574. PMID: 37504267.
      Citations: 4     Fields:    
    16. Ashktorab H, Brim H. Editorial to the Special Issue 'Nutritional Intervention in Digestive Diseases in the Era of Nutraceuticals, Nutrigenomics and Microbiomics'. Nutrients. 2023 Jun 29; 15(13). PMID: 37447291.
      Citations:    Fields:    
    17. Horwitz LI, Thaweethai T, Brosnahan SB, Cicek MS, Fitzgerald ML, Goldman JD, Hess R, Hodder SL, Jacoby VL, Jordan MR, Krishnan JA, Laiyemo AO, Metz TD, Nichols L, Patzer RE, Sekar A, Singer NG, Stiles LE, Taylor BS, Ahmed S, Algren HA, Anglin K, Aponte-Soto L, Ashktorab H, Bassett IV, Bedi B, Bhadelia N, Bime C, Bind MC, Black LJ, Blomkalns AL, Brim H, Castro M, Chan J, Charney AW, Chen BK, Chen LQ, Chen P, Chestek D, Chibnik LB, Chow DC, Chu HY, Clifton RG, Collins S, Costantine MM, Cribbs SK, Deeks SG, Dickinson JD, Donohue SE, Durstenfeld MS, Emery IF, Erlandson KM, Facelli JC, Farah-Abraham R, Finn AV, Fischer MS, Flaherman VJ, Fleurimont J, Fonseca V, Gallagher EJ, Gander JC, Gennaro ML, Gibson KS, Go M, Goodman SN, Granger JP, Greenway FL, Hafner JW, Han JE, Harkins MS, Hauser KSP, Heath JR, Hernandez CR, Ho O, Hoffman MK, Hoover SE, Horowitz CR, Hsu H, Hsue PY, Hughes BL, Jagannathan P, James JA, John J, Jolley S, Judd SE, Juskowich JJ, Kanjilal DG, Karlson EW, Katz SD, Kelly JD, Kelly SW, Kim AY, Kirwan JP, Knox KS, Kumar A, Lamendola-Essel MF, Lanca M, Lee-Lannotti JK, Lefebvre RC, Levy BD, Lin JY, Logarbo BP, Logue JK, Longo MT, Luciano CA, Lutrick K, Malakooti SK, Mallett G, Maranga G, Marathe JG, Marconi VC, Marshall GD, Martin CF, Martin JN, May HT, McComsey GA, McDonald D, Mendez-Figueroa H, Miele L, Mittleman MA, Mohandas S, Mouchati C, Mullington JM, Nadkarni GN, Nahin ER, Neuman RB, Newman LT, Nguyen A, Nikolich JZ, Ofotokun I, Ogbogu PU, Palatnik A, Palomares KTS, Parimon T, Parry S, Parthasarathy S, Patterson TF, Pearman A, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Porterfield JZ, Quigley JG, Quinn DK, Raissy H, Rebello CJ, Reddy UM, Reece R, Reeder HT, Rischard FP, Rosas JM, Rosen CJ, Rouphael NG, Rouse DJ, Ruff AM, Saint Jean C, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Selvaggi C, Seshadri S, Sesso HD, Shah DP, Shemesh E, Sherif ZA, Shinnick DJ, Simhan HN, Singh U, Sowles A, Subbian V, Sun J, Suthar MS, Teunis LJ, Thorp JM, Ticotsky A, Tita ATN, Tragus R, Tuttle KR, Urdaneta AE, Utz PJ, VanWagoner TM, Vasey A, Vernon SD, Vidal C, Walker T, Ward HD, Warren DE, Weeks RM, Weiner SJ, Weyer JC, Wheeler JL, Whiteheart SW, Wiley Z, Williams NJ, Wisnivesky JP, Wood JC, Yee LM, Young NM, Zisis SN, Foulkes AS. Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design. PLoS One. 2023; 18(6):e0286297. PMID: 37352211.
      Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
    18. Thaweethai T, Jolley SE, Karlson EW, Levitan EB, Levy B, McComsey GA, McCorkell L, Nadkarni GN, Parthasarathy S, Singh U, Walker TA, Selvaggi CA, Shinnick DJ, Schulte CCM, Atchley-Challenner R, Alba GA, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett IV, Bateman L, Bedi B, Bhattacharyya S, Bind MA, Blomkalns AL, Bonilla H, Brim H, Bush PA, Castro M, Chan J, Charney AW, Chen P, Chibnik LB, Chu HY, Clifton RG, Costantine MM, Cribbs SK, Davila Nieves SI, Deeks SG, Duven A, Emery IF, Erdmann N, Erlandson KM, Ernst KC, Farah-Abraham R, Farner CE, Feuerriegel EM, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander JC, Gardner EM, Geng LN, Gibson KS, Go M, Goldman JD, Grebe H, Greenway FL, Habli M, Hafner J, Han JE, Hanson KA, Heath J, Hernandez C, Hess R, Hodder SL, Hoffman MK, Hoover SE, Huang B, Hughes BL, Jagannathan P, John J, Jordan MR, Katz SD, Kaufman ES, Kelly JD, Kelly SW, Kemp MM, Kirwan JP, Klein JD, Knox KS, Krishnan JA, Kumar A, Laiyemo AO, Lambert AA, Lanca M, Lee-Iannotti JK, Logarbo BP, Longo MT, Luciano CA, Lutrick K, Maley JH, Mallett G, Marathe JG, Marconi V, Marshall GD, Martin CF, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz TD, Morse R, Mosier J, Mouchati C, Mullington J, Murphy SN, Neuman RB, Nikolich JZ, Ofotokun I, Ojemakinde E, Palatnik A, Palomares K, Parimon T, Parry S, Patterson JE, Patterson TF, Patzer RE, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Quigley JG, Reddy U, Reece R, Reeder H, Reeves WB, Reiman EM, Rischard F, Rosand J, Rouse DJ, Ruff A, Saade G, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Shepherd F, Sherif ZA, Simhan H, Singer NG, Skupski DW, Sowles A, Sparks JA, Sukhera FI, Taylor BS, Teunis L, Thomas RJ, Thorp JM, Thuluvath P, Ticotsky A, Tita AT, Tuttle KR, Urdaneta AE, Valdivieso D, VanWagoner TM, Vasey A, Verduzco-Gutierrez M, Wallace ZS, Ward HD, Warren DE, Weiner SJ, Welch S, Whiteheart SW, Wiley Z, Wisnivesky JP, Yee LM, Zisis S, Horwitz LI, Foulkes AS. Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. JAMA. 2023 06 13; 329(22):1934-1946. PMID: 37278994.
      Citations: 217     Fields:    Translation:HumansCells
    19. Ashktorab H, Pizuorno A, Adeleye F, Laiyemo A, Dalivand MM, Aduli F, Sherif ZA, Oskrochi G, Angesom K, Oppong-Twene P, Challa SR, Okorie N, Moon ES, Romos E, Jones-Wonni B, Kone AM, Rankine S, Thrift C, Scholes D, Ekwunazu C, Banson A, Mitchell B, Maskalo G, Ross J, Curtis J, Kim R, Gilliard C, Ahuja G, Mathew J, Gavin W, Kara A, Hache-Marliere M, Palaiodimos L, Mani VR, Kalabin A, Gayam VR, Garlapati PR, Miller J, Chirumamilla LG, Jackson F, Carethers JM, Kamangar F, Brim H. Correction: Symptomatic, clinical and?biomarker associations for?mortality in?hospitalized COVID-19 patients enriched for?African Americans. BMC Infect Dis. 2022 Aug 29; 22(1):712. PMID: 36038841.
      Citations:    Fields:    
    20. Rashid M, Brim H, Ashktorab H. Saffron, Its Active Components, and Their Association with DNA and Histone Modification: A Narrative Review of Current Knowledge. Nutrients. 2022 Aug 12; 14(16). PMID: 36014823.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    21. Ahmad S, Ashktorab H, Brim H, Housseau F. Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics? World J Gastroenterol. 2022 Jul 07; 28(25):2782-2801. PMID: 35978869.
      Citations: 2     Fields:    Translation:Humans
    22. Boudar Z, Sehli S, El Janahi S, Al Idrissi N, Hamdi S, Dini N, Brim H, Amzazi S, Nejjari C, Lloyd-Puryear M, Ghazal H. Metagenomics Approaches to Investigate the Neonatal Gut Microbiome. Front Pediatr. 2022; 10:886627. PMID: 35799697.
      Citations:    
    23. Ashktorab H, Pizuorno A, Adeleye F, Laiyemo A, Dalivand MM, Aduli F, Sherif ZA, Oskrochi G, Angesom K, Oppong-Twene P, Challa SR, Okorie N, Moon ES, Romos E, Jones-Wonni B, Kone AM, Rankine S, Thrift C, Scholes D, Ekwunazu C, Banson A, Mitchell B, Maskalo G, Ross J, Curtis J, Kim R, Gilliard C, Ahuja G, Mathew J, Gavin W, Kara A, Hache-Marliere M, Palaiodimos L, Mani VR, Kalabin A, Gayam VR, Garlapati PR, Miller J, Chirumamilla LG, Jackson F, Carethers JM, Kamangar F, Brim H. Symptomatic, clinical and biomarker associations for mortality in hospitalized COVID-19 patients enriched for African Americans. BMC Infect Dis. 2022 Jun 17; 22(1):552. PMID: 35715729.
      Citations: 6     Fields:    Translation:HumansCells
    24. Challa SR, Oskrochi G, Chirumamilla LG, Shayegh N, Brim H, Ashktorab H. Predictors of Mortality in Hospitalized African American Covid-19 Cancer Patients. Res Sq. 2022 Mar 22. PMID: 35350203.
      Citations:    
    25. Ashktorab H, Russo T, Oskrochi G, Latella G, Massironi S, Luca M, Chirumamilla LG, Laiyemo AO, Brim H. Clinical and Endoscopic Outcomes in Coronavirus Disease-2019 Patients With Gastrointestinal Bleeding. Gastro Hep Adv. 2022; 1(4):487-499. PMID: 35287301.
      Citations:    
    26. Ashktorab H, Brim H. Colorectal cancer subtyping. Nat Rev Cancer. 2022 02; 22(2):68-69. PMID: 34880443.
      Citations: 9     Fields:    Translation:Humans
    27. Mokarram P, Niknam M, Sadeghdoust M, Aligolighasemabadi F, Siri M, Dastghaib S, Brim H, Ashktorab H. PIWI interacting RNAs perspectives: a new avenues in future cancer investigations. Bioengineered. 2021 12; 12(2):10401-10419. PMID: 34723746.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    28. Brim H, Ashktorab H. Integrating microbiomics in cancer management. Nat Rev Cancer. 2021 11; 21(11):684-685. PMID: 34316056.
      Citations: 3     Fields:    Translation:Humans
    29. Ashktorab H, Folake A, Pizuorno A, Oskrochi G, Oppong-Twene P, Tamanna N, Mehdipour Dalivand M, Umeh LN, Moon ES, Kone AM, Banson A, Federman C, Ramos E, Awoyemi EO, Wonni BJ, Otto E, Maskalo G, Velez AO, Rankine S, Thrift C, Ekwunazu C, Scholes D, Chirumamilla LG, Ibrahim ME, Mitchell B, Ross J, Curtis J, Kim R, Gilliard C, Mathew J, Laiyemo A, Kibreab A, Lee E, Sherif Z, Shokrani B, Aduli F, Brim H. COVID-19 among African Americans and Hispanics: Does gastrointestinal symptoms impact the outcome? World J Clin Cases. 2021 Oct 06; 9(28):8374-8387. PMID: 34754847.
      Citations:    
    30. Pizuorno A, Brim H, Ashktorab H. Gastrointestinal manifestations and SARS-CoV-2 infection. Curr Opin Pharmacol. 2021 12; 61:114-119. PMID: 34688995.
      Citations: 5     Fields:    Translation:HumansCells
    31. Russo T, Pizuorno A, Oskrochi G, Latella G, Massironi S, Schettino M, Aghemo A, Pugliese N, Brim H, Ashktorab H. Gastrointestinal Manifestations, Clinical Characteristics and Outcomes of COVID-19 in Adult and Pediatric Patients. SOJ Microbiol Infect Dis. 2021; 8(1). PMID: 35611315.
      Citations:    
    32. Ashktorab H, Pizuorno A, Fierro NA, Villagrana EDC, Solis MEH, Cardenas G, Alvarez DZ, Oskrochi G, Adeleye F, Dalivand MM, Laiyemo AO, Aduli F, Sherif ZA, Brim H. A Comprehensive Meta-Analysis of COVID-19 in Latin America. SOJ Microbiol Infect Dis. 2021; 8(1):1-11. PMID: 35937158.
      Citations:    
    33. Chirumamilla LG, Brim H, Pizuorno A, Oskrochi G, Ashktorab H. Covid-19 and Gastrointestinal Manifestations in Indian Patients: A Meta-Analysis. SOJ Microbiol Infect Dis. 2021; 8(1):1-7. PMID: 36034468.
      Citations:    
    34. Brim H, Taylor J, Abbas M, Vilmenay K, Daremipouran M, Varma S, Lee E, Pace B, Song-Naba WL, Gupta K, Nekhai S, O'Neil P, Ashktorab H. The gut microbiome in sickle cell disease: Characterization and potential implications. PLoS One. 2021; 16(8):e0255956. PMID: 34432825.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    35. Brim A, Ashktorab Y, Russo T, Pizuorno A, Oskrochi G, Brim H. Pediatric COVID-19 and Gastrointestinal Symptoms in Africa. Gastroenterology. 2021 12; 161(6):2047-2050.e3. PMID: 34418440.
      Citations: 2     Fields:    Translation:HumansCells
    36. Singh G, Haileselassie Y, Ji AR, Maecker HT, Sinha SR, Brim H, Habtezion A, Ashktorab H. Protective Effect of Saffron in Mouse Colitis Models Through Immune Modulation. Dig Dis Sci. 2022 07; 67(7):2922-2935. PMID: 34275090.
      Citations: 11     Fields:    Translation:HumansAnimals
    37. Mokarram P, Dalivand MM, Pizuorno A, Aligolighasemabadi F, Sadeghdoust M, Sadeghdoust E, Aduli F, Oskrochi G, Brim H, Ashktorab H. Clinical characteristics, gastrointestinal manifestations and outcomes of COVID-19 patients in Iran; does the location matters? World J Clin Cases. 2021 Jun 26; 9(18):4654-4667. PMID: 34222432.
      Citations:    
    38. Amin A, Farrukh A, Murali C, Soleimani A, Praz F, Graziani G, Brim H, Ashktorab H. Saffron and Its Major Ingredients' Effect on Colon Cancer Cells with Mismatch Repair Deficiency and Microsatellite Instability. Molecules. 2021 Jun 24; 26(13). PMID: 34202689.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    39. Pizuorno A, Fierro NA, Copado-Villagrana ED, Herrera-Sol?s ME, Oskrochi G, Brim H, Ashktorab H. COVID-19 and gastrointestinal symptoms in Mexico, a systematic review: does location matter? BMC Infect Dis. 2021 Jun 11; 21(1):555. PMID: 34116647.
      Citations: 4     Fields:    Translation:HumansCells
    40. Banskota S, Brim H, Kwon YH, Singh G, Sinha SR, Wang H, Khan WI, Ashktorab H. Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice. Molecules. 2021 Jun 02; 26(11). PMID: 34199466.
      Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    41. Ashktorab H, Brim H. Blood-Based Liquid Biopsies: A Noninvasive and Cost-Effective Tool for Improved Risk Assessment and Identification of Lymph Node Metastasis in Patients With Submucosal T1 Colorectal Cancer. Gastroenterology. 2021 07; 161(1):29-31. PMID: 33895167.
      Citations: 4     Fields:    Translation:Humans
    42. Ashktorab H, Pizuorno A, Aduli F, Laiyemo AO, Oskrochi G, Brim H. Elevated Liver Enzymes, Ferritin, C-reactive Protein, D-dimer, and Age Are Predictive Markers of Outcomes Among African American and Hispanic Patients With Coronavirus Disease 2019. Gastroenterology. 2021 07; 161(1):345-349. PMID: 33811923.
      Citations: 5     Fields:    Translation:Humans
    43. Sherif ZA, Nouraie SM, Lee E, Aduli F, Brim H, Ashktorab H. Trends in the Incidence of Hepatocellular Carcinoma in Washington DC: A Single Institutional Cohort Study (1959-2013). J Natl Med Assoc. 2021 Aug; 113(4):396-404. PMID: 33648723.
      Citations: 1     Fields:    Translation:Humans
    44. Ashktorab H, Pizuomo A, Gonz?lez NAF, Villagrana EDC, Herrera-Sol?s ME, Cardenas G, Zavala-Alvarez D, Oskrochi G, Awoyemi E, Adeleye F, Dalivand MM, Laiyemo AO, Lee EE, Aduli F, Sherif ZA, Brim H. A Comprehensive Analysis of COVID-19 Impact in Latin America. Res Sq. 2021 Jan 08. PMID: 33442675.
      Citations:    
    45. Ashktorab Y, Brim A, Pizuorno A, Gayam V, Nikdel S, Brim H. COVID-19 Pediatric Patients: Gastrointestinal Symptoms, Presentations, and Disparities by Race/Ethnicity in a Large, Multicenter US Study. Gastroenterology. 2021 04; 160(5):1842-1844. PMID: 33421514.
      Citations: 5     Fields:    Translation:HumansCells
    46. Ashktorab H, Pizuorno A, Oskroch G, Fierro NA, Sherif ZA, Brim H. COVID-19 in Latin America: Symptoms, Morbidities, and Gastrointestinal Manifestations. Gastroenterology. 2021 02; 160(3):938-940. PMID: 33160964.
      Citations: 12     Fields:    Translation:Humans
    47. Brim H, Mirabello L, Bass S, Ford DH, Carethers JM, Ashktorab H. Association of Human Papillomavirus Genotype 16 Lineages With Anal Cancer Histologies Among African Americans. Gastroenterology. 2021 02; 160(3):922-924. PMID: 33075347.
      Citations: 2     Fields:    Translation:HumansCells
    48. Chawla K, Kibreab A, Scott V, Lee EL, Aduli F, Brim H, Ashktorab H, Howell CD, Laiyemo AO. Association of Patients' Perception of Quality of Healthcare Received and Colorectal Cancer Screening Uptake: An Analysis of 2 National Surveys in the USA. Med Princ Pract. 2021; 30(4):331-338. PMID: 33049736.
      Citations: 2     Fields:    Translation:Humans
    49. Shokrani B, Brim H, Hydari T, Afsari A, Lee E, Nouraie M, Sherif Z, Ashktorab H. Analysis of ?-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions. BMC Gastroenterol. 2020 Aug 18; 20(1):274. PMID: 32811441.
      Citations: 2     Fields:    Translation:HumansCells
    50. G?ll? N, Kobelt D, Brim H, Rahman S, Timm L, Smith J, Soleimani A, Di Marco S, Bisti S, Ashktorab H, Stein U. Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells. Cells. 2020 08 03; 9(8). PMID: 32756469.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    51. Ashktorab H, Brim H, Hassan S, Nouraie M, Gebreselassie A, Laiyemo AO, Kibreab A, Aduli F, Latella G, Brant SR, Sherif Z, Habtezion A. Inflammatory polyps occur more frequently in inflammatory bowel disease than other colitis patients. BMC Gastroenterol. 2020 Jun 05; 20(1):170. PMID: 32503428.
      Citations: 8     Fields:    Translation:Humans
    52. Ashktorab H, Washington K, Zarnogi S, Shakoori A, Varma S, Lee E, Shokrani B, Laiyemo A, Brim H. Determination of distinctive hypomethylated genes in African American colorectal neoplastic lesions. Therap Adv Gastroenterol. 2020; 13:1756284820905482. PMID: 32547637.
      Citations:    
    53. Erfani M, Hosseini SV, Mokhtari M, Zamani M, Tahmasebi K, Alizadeh Naini M, Taghavi A, Carethers JM, Koi M, Brim H, Mokarram P, Ashktorab H. Altered ARID1A expression in colorectal cancer. BMC Cancer. 2020 Apr 25; 20(1):350. PMID: 32334542.
      Citations: 17     Fields:    Translation:HumansCells
    54. Laiyemo AO, Idowu KA, Burnside C, Williams CD, Jack M, Mekasha G, Ashktorab H, Brim H, Lee EL, Sanderson AK, Kibreab A, Kwagyan J. Comparison of patterns of laxative ingestion to improve bowel preparation for colonoscopy: a pilot randomized clinical trial. Endosc Int Open. 2020 May; 8(5):E617-E622. PMID: 32355879.
      Citations:    
    55. Sherif ZA, Nouraie M, Begum R, Afsari A, Shokrani B, Lee E, Laiyemo AO, Brim H, Ashktorab H. Factors influencing treatment outcome in hepatitis C virus minority patients at an inner-city hospital: A STROBE-complaint article. Medicine (Baltimore). 2020 Apr; 99(14):e19505. PMID: 32243366.
      Citations: 1     Fields:    Translation:Humans
    56. Abbas M, Mason T, Ibad A, Khraiwesh M, Apprey V, Kanaan Y, Wilson B, Dunston G, Ricks-Santi L, Brim H. Genetic Polymorphisms in IL-10 Promoter Are Associated With Smoking and Prostate Cancer Risk in African Americans. Anticancer Res. 2020 Jan; 40(1):27-34. PMID: 31892550.
      Citations: 2     Fields:    Translation:HumansCells
    57. Ashktorab H, Sherif Z, Tarjoman T, Azam S, Lee E, Shokrani B, Okereke I, Soleimani A, Carethers JM, Laiyemo AO, Aduli F, Nouraie M, Habtezion A, Brim H. Elevated Risk for Sessile Serrated Polyps in African Americans with Endometrial Polyps. Dig Dis Sci. 2020 09; 65(9):2686-2690. PMID: 31832971.
      Citations: 3     Fields:    Translation:Humans
    58. Laiyemo AO, Kwagyan J, Williams CD, Rogers J, Kibreab A, Jack MA, Lee EE, Brim H, Ashktorab H, Howell CD, Smoot DT, Platz EA. Using Patients' Social Network to Improve Compliance to Outpatient Screening Colonoscopy Appointments Among Blacks: A Randomized Clinical Trial. Am J Gastroenterol. 2019 10; 114(10):1671-1677. PMID: 31478919.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    59. Nouraie M, Ashktorab H, Atefi N, Azam S, Tarjoman T, Lee E, Shokrani B, Afsari A, Soleimani A, Laiyemo AO, Singh S, Brim H. Can the rate and location of sessile serrated polyps be part of colorectal Cancer disparity in African Americans? BMC Gastroenterol. 2019 May 24; 19(1):77. PMID: 31126232.
      Citations: 3     Fields:    Translation:Humans
    60. Ashktorab H, Soleimani A, Singh G, Amin A, Tabtabaei S, Latella G, Stein U, Akhondzadeh S, Solanki N, Gondr?-Lewis MC, Habtezion A, Brim H. Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases. Nutrients. 2019 04 26; 11(5). PMID: 31027364.
      Citations: 50     Fields:    Translation:HumansAnimals
    61. Ashktorab H, Delker D, Kanth P, Goel A, Carethers JM, Brim H. Molecular Characterization of Sessile Serrated Adenoma/Polyps From a Large African American Cohort. Gastroenterology. 2019 08; 157(2):572-574. PMID: 31004568.
      Citations: 9     Fields:    Translation:Humans
    62. Ashktorab H, Azimi H, Varma S, Lee EL, Laiyemo AO, Nickerson ML, Brim H. Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia. Oncotarget. 2019 Apr 05; 10(27):2607-2624. PMID: 31080553.
      Citations: 6     Fields:    
    63. Ashktorab H, Rahi H, Nouraie M, Shokrani B, Lee E, Haydari T, Laiyemo AO, Siegel P, Brim H. GPNMB methylation: a new marker of potentially carcinogenic colon lesions. BMC Cancer. 2018 Nov 06; 18(1):1068. PMID: 30400781.
      Citations: 5     Fields:    Translation:HumansCells
    64. Shahnazi A, Badurdeen D, Laiyemo AO, Nouraie M, Brim H, Wessly P, Geramfard S, Afsari A, Page N, Ashktorab H. Obesity and Pancreatic Cysts in African American Patients. Cureus. 2018 Aug 20; 10(8):e3160. PMID: 30357033.
      Citations:    
    65. Brim H, Shahnazi A, Nouraie M, Badurdeen D, Laiyemo AO, Haidary T, Afsari A, Ashktorab H. Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia. Clin Med Insights Gastroenterol. 2018; 11:1179552218778627. PMID: 29795991.
      Citations:    
    66. Ashktorab H, Soleimani A, Nichols A, Sodhi K, Laiyemo AO, Nunlee-Bland G, Nouraie SM, Brim H. Adiponectin, Leptin, IGF-1, and Tumor Necrosis Factor Alpha As Potential Serum Biomarkers for Non-Invasive Diagnosis of Colorectal Adenoma in African Americans. Front Endocrinol (Lausanne). 2018; 9:77. PMID: 29593647.
      Citations: 4     Fields:    
    67. Brim H, Yooseph S, Lee E, Sherif ZA, Abbas M, Laiyemo AO, Varma S, Torralba M, Dowd SE, Nelson KE, Pathmasiri W, Sumner S, de Vos W, Liang Q, Yu J, Zoetendal E, Ashktorab H. A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation. Genes (Basel). 2017 11 09; 8(11). PMID: 29120399.
      Citations: 11     Fields:    
    68. Ashktorab H, Azimi H, Varma S, Tavakoli P, Nickerson ML, Brim H. Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia. Oncotarget. 2017 Nov 21; 8(59):99966-99977. PMID: 29245953.
      Citations: 4     Fields:    
    69. Ashktorab H, Kupfer SS, Brim H, Carethers JM. Racial Disparity in Gastrointestinal Cancer Risk. Gastroenterology. 2017 10; 153(4):910-923. PMID: 28807841.
      Citations: 125     Fields:    Translation:Humans
    70. Afsari A, Lee E, Shokrani B, Boortalary T, Sherif ZA, Nouraie M, Laiyemo AO, Alkhalloufi K, Brim H, Ashktorab H. Clinical and Pathological Risk Factors Associated with Liver Fibrosis and Steatosis in African-Americans with Chronic Hepatitis C. Dig Dis Sci. 2017 08; 62(8):2159-2165. PMID: 28612194.
      Citations: 4     Fields:    Translation:HumansCells
    71. Sanabria-Salas MC, Hern?ndez-Su?rez G, Uma?a-P?rez A, Rawlik K, Tenesa A, Serrano-L?pez ML, S?nchez de G?mez M, Rojas MP, Bravo LE, Albis R, Plata JL, Green H, Borgovan T, Li L, Majumdar S, Garai J, Lee E, Ashktorab H, Brim H, Li L, Margolin D, Fejerman L, Zabaleta J. IL1B-CGTC haplotype is associated with colorectal cancer in admixed individuals with increased African ancestry. Sci Rep. 2017 02 03; 7:41920. PMID: 28157220.
      Citations: 7     Fields:    Translation:HumansCells
    72. Ashktorab H, Mokarram P, Azimi H, Olumi H, Varma S, Nickerson ML, Brim H. Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer. Oncotarget. 2017 Jan 31; 8(5):7852-7866. PMID: 28002797.
      Citations: 17     Fields:    Translation:Cells
    73. Liang Q, Chiu J, Chen Y, Huang Y, Higashimori A, Fang J, Brim H, Ashktorab H, Ng SC, Ng SSM, Zheng S, Chan FKL, Sung JJY, Yu J. Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer. Clin Cancer Res. 2017 04 15; 23(8):2061-2070. PMID: 27697996.
      Citations: 159     Fields:    Translation:Humans
    74. Brim H, Ashktorab H. Genomics of Colorectal Cancer in African Americans. Next Gener Seq Appl. 2016 Sep; 3(2). PMID: 27917406.
      Citations:    
    75. Ashktorab H, Shakoori A, Zarnogi S, Sun X, Varma S, Lee E, Shokrani B, Laiyemo AO, Washington K, Brim H. Reduced Representation Bisulfite Sequencing Determination of Distinctive DNA Hypermethylated Genes in the Progression to Colon Cancer in African Americans. Gastroenterol Res Pract. 2016; 2016:2102674. PMID: 27688749.
      Citations:    
    76. Ashktorab H, Etaati F, Rezaeean F, Nouraie M, Paydar M, Namin HH, Sanderson A, Begum R, Alkhalloufi K, Brim H, Laiyemo AO. Can optical diagnosis of small colon polyps be accurate? Comparing standard scope without narrow banding to high definition scope with narrow banding. World J Gastroenterol. 2016 Jul 28; 22(28):6539-46. PMID: 27605888.
      Citations: 2     Fields:    Translation:Humans
    77. Ashktorab H, Hermann P, Nouraie M, Shokrani B, Lee E, Haidary T, Brim H, Stein U. Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk. J Transl Med. 2016 07 20; 14(1):215. PMID: 27439755.
      Citations: 12     Fields:    Translation:Humans
    78. Ashktorab H, Vilmenay K, Brim H, Laiyemo AO, Kibreab A, Nouraie M. Colorectal Cancer in Young African Americans: Is It Time to Revisit Guidelines and Prevention? Dig Dis Sci. 2016 10; 61(10):3026-3030. PMID: 27278956.
      Citations: 30     Fields:    Translation:Humans
    79. Abbas M, Berka N, Khraiwesh M, Ramadan A, Apprey V, Furbert-Harris P, Quinn T, Brim H, Dunston G. Genetic Polymorphisms of TLR4 and MICA are Associated with Severity of Trachoma Disease in Tanzania. Autoimmune Infect Dis. 2016 Jun; 2(3). PMID: 27559544.
      Citations:    
    80. Ashktorab H, Ahuja S, Kannan L, Llor X, Ellis NA, Xicola RM, Laiyemo AO, Carethers JM, Brim H, Nouraie M. A meta-analysis of MSI frequency and race in colorectal cancer. Oncotarget. 2016 Apr 23; 7(23):34546-57. PMID: 27120810.
      Citations: 57     Fields:    Translation:Humans
    81. Shahnazi A, Sanderson AK, Laiyemo AO, Nouraie M, Haidary T, Brim H, Geramfard S, Afsari A, Ashktorab H. Diabetes Mellitus and Pancreatic Cysts in African Americans. Pancreas. 2016 Apr; 45(4):e14-5. PMID: 26954497.
      Citations:    Fields:    Translation:Humans
    82. Sherif ZA, Saeed A, Ghavimi S, Nouraie SM, Laiyemo AO, Brim H, Ashktorab H. Global Epidemiology of Nonalcoholic Fatty Liver Disease and Perspectives on US Minority Populations. Dig Dis Sci. 2016 May; 61(5):1214-25. PMID: 27038448.
      Citations: 84     Fields:    Translation:Humans
    83. Ashktorab H, Azimi H, Nickerson ML, Bass S, Varma S, Brim H. Targeted Exome Sequencing Outcome Variations of Colorectal Tumors within and across Two Sequencing Platforms. Next Gener Seq Appl. 2016 Jun; 3(1). PMID: 27547838.
      Citations:    
    84. Ashktorab H, Ogundipe T, Brim H, Shahnazi A, Laiyemo AO, Lee E, Shokrani B, Nouraie M. Lymph nodes' evaluation in relation to colorectal cancer staging among African Americans. BMC Cancer. 2015 Dec 16; 15:976. PMID: 26673446.
      Citations: 2     Fields:    Translation:Humans
    85. Ashktorab H, Laiyemo AO, Lee E, Cruz-Correa M, Ghuman A, Nouraie M, Brim H. Prevalence and features of colorectal lesions among Hispanics: A hospital-based study. World J Gastroenterol. 2015 Dec 14; 21(46):13095-100. PMID: 26673447.
      Citations: 5     Fields:    Translation:Humans
    86. Laiyemo AO, Thompson N, Williams CD, Idowu KA, Bull-Henry K, Sherif ZA, Lee EL, Brim H, Ashktorab H, Platz EA, Smoot DT. Race and colorectal cancer screening compliance among persons with a family history of cancer. World J Gastrointest Endosc. 2015 Dec 10; 7(18):1300-5. PMID: 26672497.
      Citations:    
    87. Nayani R, Ashktorab H, Brim H, Laiyemo AO. Genetic Basis for Colorectal Cancer Disparities. Curr Colorectal Cancer Rep. 2015 Dec 01; 11(6):408-413. PMID: 26997937.
      Citations:    
    88. Nouraie M, Kansal V, Belfonte C, Ghazvini M, Haidari T, Shahnazi A, Brim H, Soliman EZ, Ashktorab H. Atrial Fibrillation and Colonic Neoplasia in African Americans. PLoS One. 2015; 10(8):e0135609. PMID: 26317627.
      Citations: 2     Fields:    Translation:Humans
    89. Ashktorab H, Panchal H, Shokrani B, Paydar M, Sanderson A, Lee EL, Begum R, Haidary T, Laiyemo AO, McDonald-Pinkett S, Brim H, Nouraie M. Association between Diverticular Disease and Pre-Neoplastic Colorectal Lesions in an Urban African-American Population. Digestion. 2015; 92(2):60-5. PMID: 26183208.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    90. Ashktorab H, Varma S, Brim H. Next-generation sequencing in African Americans with colorectal cancer. Proc Natl Acad Sci U S A. 2015 Jun 02; 112(22):E2852. PMID: 25941412.
      Citations: 7     Fields:    Translation:Humans
    91. Ashktorab H, Brim H. DNA Methylation and Colorectal Cancer. Curr Colorectal Cancer Rep. 2014 Dec 01; 10(4):425-430. PMID: 25580099.
      Citations:    
    92. Ashktorab H, Daremipouran M, Devaney J, Varma S, Rahi H, Lee E, Shokrani B, Schwartz R, Nickerson ML, Brim H. Identification of novel mutations by exome sequencing in African American colorectal cancer patients. Cancer. 2015 Jan 01; 121(1):34-42. PMID: 25250560.
      Citations: 26     Fields:    Translation:HumansCells
    93. Laiyemo AO, Williams CD, Burnside C, Moghadam S, Sanasi-Bhola KD, Kwagyan J, Brim H, Ashktorab H, Scott VF, Smoot DT. Factors associated with attendance to scheduled outpatient endoscopy. Postgrad Med J. 2014 Oct; 90(1068):571-5. PMID: 25180285.
      Citations: 9     Fields:    Translation:Humans
    94. Brim H, Zahaf M, Laiyemo AO, Nouraie M, P?rez-P?rez GI, Smoot DT, Lee E, Razjouyan H, Ashktorab H. Gastric Helicobacter pylori infection associates with an increased risk of colorectal polyps in African Americans. BMC Cancer. 2014 Apr 28; 14:296. PMID: 24774100.
      Citations: 20     Fields:    Translation:HumansCells
    95. Ashktorab H, Paydar M, Yazdi S, Namin HH, Sanderson A, Begum R, Semati M, Etaati F, Lee E, Brim H, Zenebe A, Nunlee-Bland G, Laiyemo AO, Nouraie M. BMI and the risk of colorectal adenoma in African-Americans. Obesity (Silver Spring). 2014 May; 22(5):1387-91. PMID: 24519988.
      Citations: 17     Fields:    Translation:Humans
    96. Brim H, Abu-Asab MS, Nouraie M, Salazar J, Deleo J, Razjouyan H, Mokarram P, Schaffer AA, Naghibhossaini F, Ashktorab H. An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors. PLoS One. 2014; 9(1):e82185. PMID: 24475022.
      Citations: 21     Fields:    Translation:HumansCells
    97. Ashktorab H, Daremipouran M, Goel A, Varma S, Leavitt R, Sun X, Brim H. DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia. Epigenetics. 2014 Apr; 9(4):503-12. PMID: 24441198.
      Citations: 45     Fields:    Translation:HumansCells
    98. Brim H, Yooseph S, Zoetendal EG, Lee E, Torralbo M, Laiyemo AO, Shokrani B, Nelson K, Ashktorab H. Microbiome analysis of stool samples from African Americans with colon polyps. PLoS One. 2013; 8(12):e81352. PMID: 24376500.
      Citations: 29     Fields:    Translation:HumansCells
    99. Fatemi M, Paul TA, Brodeur GM, Shokrani B, Brim H, Ashktorab H. Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages. Cancer. 2014 Jan 15; 120(2):172-80. PMID: 24243398.
      Citations: 35     Fields:    Translation:HumansCells
    100. Ashktorab H, Paydar M, Namin HH, Sanderson A, Begum R, Brim H, Panchal H, Lee E, Kibreab A, Nouraie M, Laiyemo AO. Prevalence of colorectal neoplasia among young African Americans and Hispanic Americans. Dig Dis Sci. 2014 Feb; 59(2):446-50. PMID: 24193352.
      Citations: 16     Fields:    Translation:Humans
    101. Ashktorab H, Rahi H, Wansley D, Varma S, Shokrani B, Lee E, Daremipouran M, Laiyemo A, Goel A, Carethers JM, Brim H. Toward a comprehensive and systematic methylome signature in colorectal cancers. Epigenetics. 2013 Aug; 8(8):807-15. PMID: 23975090.
      Citations: 36     Fields:    Translation:HumansCells
    102. Ashktorab H, Hassanzadeh Namin H, Taylor T, Williams C, Brim H, Mellman T, Shokrani B, Holt CL, Laiyemo AO, Nouraie M. Role of life events in the presence of colon polyps among African Americans. BMC Gastroenterol. 2013 Jun 12; 13:101. PMID: 23758671.
      Citations: 3     Fields:    Translation:Humans
    103. Errami Y, Brim H, Oumouna-Benachour K, Oumouna M, Naura AS, Kim H, Ju J, Davis CJ, Kim JG, Ashktorab H, Fallon K, Xu M, Zhang J, Del Valle L, Boulares AH. ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability. PLoS One. 2013; 8(2):e57871. PMID: 23451280.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    104. Laiyemo AO, Doubeni C, Brim H, Ashktorab H, Schoen RE, Gupta S, Charabaty A, Lanza E, Smoot DT, Platz E, Cross AJ. Short- and long-term risk of colorectal adenoma recurrence among whites and blacks. Gastrointest Endosc. 2013 Mar; 77(3):447-54. PMID: 23337636.
      Citations: 16     Fields:    Translation:Humans
    105. Errami Y, Naura AS, Kim H, Ju J, Suzuki Y, El-Bahrawy AH, Ghonim MA, Hemeida RA, Mansy MS, Zhang J, Xu M, Smulson ME, Brim H, Boulares AH. Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonuclease that translocates to the nucleus during apoptosis. J Biol Chem. 2013 Feb 01; 288(5):3460-8. PMID: 23229555.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    106. Ashktorab H, Entezari O, Nouraie M, Dowlati E, Frederick W, Woods A, Lee E, Brim H, Smoot DT, Ghadyari F, Kamangar F, Razjouyan H. Helicobacter pylori protection against reflux esophagitis. Dig Dis Sci. 2012 Nov; 57(11):2924-8. PMID: 23010740.
      Citations: 10     Fields:    Translation:HumansCells
    107. Brim H, Lee E, Abu-Asab MS, Chaouchi M, Razjouyan H, Namin H, Goel A, Sch?ffer AA, Ashktorab H. Genomic aberrations in an African American colorectal cancer cohort reveals a MSI-specific profile and chromosome X amplification in male patients. PLoS One. 2012; 7(8):e40392. PMID: 22879877.
      Citations: 24     Fields:    Translation:HumansCells
    108. Ashktorab H, Green W, Finzi G, Sessa F, Nouraie M, Lee EL, Morgano A, Moschetta A, Cattaneo M, Mariani-Costantini R, Brim H, Biunno I. SEL1L, an UPR response protein, a potential marker of colonic cell transformation. Dig Dis Sci. 2012 Apr; 57(4):905-12. PMID: 22350780.
      Citations: 14     Fields:    Translation:HumansCells
    109. Ashktorab H, Nguza B, Fatemi M, Nouraie M, Smoot DT, Sch?ffer AA, Kupfer SS, Camargo CA, Brim H. Case-control study of vitamin D, dickkopf homolog 1 (DKK1) gene methylation, VDR gene polymorphism and the risk of colon adenoma in African Americans. PLoS One. 2011; 6(10):e25314. PMID: 22022386.
      Citations: 12     Fields:    Translation:HumansCells
    110. Ashktorab H, Nouri Z, Nouraie M, Razjouyan H, Lee EE, Dowlati E, El-Seyed el-W, Laiyemo A, Brim H, Smoot DT. Esophageal carcinoma in African Americans: a five-decade experience. Dig Dis Sci. 2011 Dec; 56(12):3577-82. PMID: 21847566.
      Citations: 11     Fields:    Translation:Humans
    111. Brim H, Kumar K, Nazarian J, Hathout Y, Jafarian A, Lee E, Green W, Smoot D, Park J, Nouraie M, Ashktorab H. SLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomas. PLoS One. 2011; 6(6):e20216. PMID: 21687703.
      Citations: 16     Fields:    Translation:HumansCells
    112. Nouraie M, Hosseinkhah F, Brim H, Zamanifekri B, Smoot DT, Ashktorab H. Clinicopathological features of colon polyps from African-Americans. Dig Dis Sci. 2010 May; 55(5):1442-9. PMID: 20225129.
      Citations: 23     Fields:    Translation:Humans
    113. Ashktorab H, Sch?ffer AA, Daremipouran M, Smoot DT, Lee E, Brim H. Distinct genetic alterations in colorectal cancer. PLoS One. 2010 Jan 26; 5(1):e8879. PMID: 20126641.
      Citations: 69     Fields:    Translation:HumansCells
    114. Mokarram P, Kumar K, Brim H, Naghibalhossaini F, Saberi-firoozi M, Nouraie M, Green R, Lee E, Smoot DT, Ashktorab H. Distinct high-profile methylated genes in colorectal cancer. PLoS One. 2009 Sep 11; 4(9):e7012. PMID: 19750230.
      Citations: 80     Fields:    Translation:HumansCells
    115. Kumar K, Brim H, Giardiello F, Smoot DT, Nouraie M, Lee EL, Ashktorab H. Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans. Clin Cancer Res. 2009 Feb 15; 15(4):1155-61. PMID: 19190129.
      Citations: 44     Fields:    Translation:HumansCells
    116. Ashktorab H, Belgrave K, Hosseinkhah F, Brim H, Nouraie M, Takkikto M, Hewitt S, Lee EL, Dashwood RH, Smoot D. Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma. Dig Dis Sci. 2009 Oct; 54(10):2109-17. PMID: 19057998.
      Citations: 56     Fields:    Translation:HumansCells
    117. Brim H, Mokarram P, Naghibalhossaini F, Saberi-Firoozi M, Al-Mandhari M, Al-Mawaly K, Al-Mjeni R, Al-Sayegh A, Raeburn S, Lee E, Giardiello F, Smoot DT, Vilkin A, Boland CR, Goel A, Hafezi M, Nouraie M, Ashktorab H. Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study. Mol Cancer. 2008 Aug 21; 7:68. PMID: 18718023.
      Citations: 47     Fields:    Translation:Humans
    118. Ashktorab H, Brim H, Al-Riyami M, Date A, Al-Mawaly K, Kashoub M, Al-Mjeni R, Smoot DT, Al-Moundhri M, Al-Hashemi S, Ganguly SS, Raeburn S. Sporadic colon cancer: mismatch repair immunohistochemistry and microsatellite instability in Omani subjects. Dig Dis Sci. 2008 Oct; 53(10):2723-31. PMID: 18299982.
      Citations: 19     Fields:    Translation:HumansCells
    119. Sultan AS, Brim H, Sherif ZA. Co-overexpression of Janus kinase 2 and signal transducer and activator of transcription 5a promotes differentiation of mammary cancer cells through reversal of epithelial-mesenchymal transition. Cancer Sci. 2008 Feb; 99(2):272-9. PMID: 18271926.
      Citations: 34     Fields:    Translation:HumansCells
    120. Brim H, Osborne JP, Kostandarithes HM, Fredrickson JK, Wackett LP, Daly MJ. Deinococcus radiodurans engineered for complete toluene degradation facilitates Cr(VI) reduction. Microbiology (Reading). 2006 Aug; 152(Pt 8):2469-2477. PMID: 16849809.
      Citations: 17     Fields:    Translation:Cells
    121. Qin J, Song L, Brim H, Daly MJ, Summers AO. Hg(II) sequestration and protection by the MerR metal-binding domain (MBD). Microbiology (Reading). 2006 Mar; 152(Pt 3):709-719. PMID: 16514151.
      Citations: 3     Fields:    Translation:Cells
    122. Ghosal D, Omelchenko MV, Gaidamakova EK, Matrosova VY, Vasilenko A, Venkateswaran A, Zhai M, Kostandarithes HM, Brim H, Makarova KS, Wackett LP, Fredrickson JK, Daly MJ. How radiation kills cells: survival of Deinococcus radiodurans and Shewanella oneidensis under oxidative stress. FEMS Microbiol Rev. 2005 Apr; 29(2):361-75. PMID: 15808748.
      Citations: 103     Fields:    Translation:Cells
    123. Brim H, Venkateswaran A, Kostandarithes HM, Fredrickson JK, Daly MJ. Engineering Deinococcus geothermalis for bioremediation of high-temperature radioactive waste environments. Appl Environ Microbiol. 2003 Aug; 69(8):4575-82. PMID: 12902245.
      Citations: 36     Fields:    Translation:CellsPHPublic Health
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