"Cell Degranulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of losing secretory granules (SECRETORY VESICLES). This occurs, for example, in mast cells, basophils, neutrophils, eosinophils, and platelets when secretory products are released from the granules by EXOCYTOSIS.
| Descriptor ID |
D015550
|
| MeSH Number(s) |
G04.468.160
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cell Degranulation".
Below are MeSH descriptors whose meaning is more specific than "Cell Degranulation".
This graph shows the total number of publications written about "Cell Degranulation" by people in this website by year, and whether "Cell Degranulation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Degranulation" by people in Profiles.
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Trivedi NH, Guentzel MN, Rodriguez AR, Yu JJ, Forsthuber TG, Arulanandam BP. Mast cells: multitalented facilitators of protection against bacterial pathogens. Expert Rev Clin Immunol. 2013 Feb; 9(2):129-38.
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Matsui T, Nunomura S, Shimokawa T, Yoshimaru T, Ra C. Functionality of the IgA Fc receptor (FcalphaR, CD89) is down-regulated by extensive engagement of FcepsilonRI. Clin Immunol. 2008 Oct; 129(1):155-62.
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Miyazaki D, Nakamura T, Toda M, Cheung-Chau KW, Richardson RM, Ono SJ. Macrophage inflammatory protein-1alpha as a costimulatory signal for mast cell-mediated immediate hypersensitivity reactions. J Clin Invest. 2005 Feb; 115(2):434-42.
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Toda M, Dawson M, Nakamura T, Munro PM, Richardson RM, Bailly M, Ono SJ. Impact of engagement of FcepsilonRI and CC chemokine receptor 1 on mast cell activation and motility. J Biol Chem. 2004 Nov 12; 279(46):48443-8.
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Vines CM, Prossnitz ER. Mechanisms of G protein-coupled receptor-mediated degranulation. FEMS Microbiol Lett. 2004 Jul 01; 236(1):1-6.
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Vines CM, Xue M, Maestas DC, Cimino DF, Prossnitz ER. Regulation of N-formyl peptide-mediated degranulation by receptor phosphorylation. J Immunol. 2002 Dec 15; 169(12):6760-6.
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Suzuki Y, Yoshimaru T, Matsui T, Ra C. Silver activates calcium signals in rat basophilic leukemia-2H3 mast cells by a mechanism that differs from the Fc epsilon RI-activated response. J Immunol. 2002 Oct 01; 169(7):3954-62.
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Tibbles HE, Navara CS, Hupke MA, Vassilev AO, Uckun FM. Thrombopoietin induces p-selectin expression on platelets and subsequent platelet/leukocyte interactions. Biochem Biophys Res Commun. 2002 Apr 12; 292(4):987-91.
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Samms M, Philp D, Emanus F, Osuji O, Pezzano M, Guyden JC. Lysosomal-mediated degradation of apoptotic thymocytes within thymic nurse cells. Cell Immunol. 1999 Nov 01; 197(2):108-15.