"Urethane" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antineoplastic agent that is also used as a veterinary anesthetic. It has also been used as an intermediate in organic synthesis. Urethane is suspected to be a carcinogen.
| Descriptor ID |
D014520
|
| MeSH Number(s) |
D02.241.081.251.944
|
| Concept/Terms |
Urethane- Urethane
- Ethyl Carbamate
- Carbamate, Ethyl
- Urethan
|
Below are MeSH descriptors whose meaning is more general than "Urethane".
Below are MeSH descriptors whose meaning is more specific than "Urethane".
This graph shows the total number of publications written about "Urethane" by people in this website by year, and whether "Urethane" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
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Below are the most recent publications written about "Urethane" by people in Profiles.
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Hoffler U, Ghanayem BI. Increased bioaccumulation of urethane in CYP2E1-/- versus CYP2E1+/+ mice. Drug Metab Dispos. 2005 Aug; 33(8):1144-50.
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Hoffler U, Dixon D, Peddada S, Ghanayem BI. Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice. Mutat Res. 2005 May 02; 572(1-2):58-72.
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Hoffler U, El-Masri HA, Ghanayem BI. Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice. J Pharmacol Exp Ther. 2003 May; 305(2):557-64.
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Stewart M, Quirk GJ, Barry M, Fox SE. Firing relations of medial entorhinal neurons to the hippocampal theta rhythm in urethane anesthetized and walking rats. Exp Brain Res. 1992; 90(1):21-8.
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Rucker HK, Corbus MJ, Pirch JH. Discriminative conditioning-related slow potential and single-unit responses in the frontal cortex of urethane-anesthetized rats. Brain Res. 1986 Jun 25; 376(2):368-72.