"Trifluridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)
Descriptor ID |
D014271
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MeSH Number(s) |
D03.383.742.680.705.900 D13.570.230.855.900 D13.570.685.705.900
|
Concept/Terms |
Trifluridine- Trifluridine
- Trifluorothymidine
- 2'-deoxy-5-(trifluoromethyl)uridine
- Trifluoridine
- 5-Trifluoromethyl-2'-deoxyuridine
- 5 Trifluoromethyl 2' deoxyuridine
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Below are MeSH descriptors whose meaning is more general than "Trifluridine".
Below are MeSH descriptors whose meaning is more specific than "Trifluridine".
This graph shows the total number of publications written about "Trifluridine" by people in this website by year, and whether "Trifluridine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Trifluridine" by people in Profiles.
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Hobden JA, Kumar M, Kaufman HE, Clement C, Varnell ED, Bhattacharjee PS, Hill JM. In vitro synergism of trifluorothymidine and ganciclovir against HSV-1. Invest Ophthalmol Vis Sci. 2011 Feb; 52(2):830-3.
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Bhattacharjee PS, Neumann DM, Foster TP, Clement C, Singh G, Thompson HW, Kaufman HE, Hill JM. Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye model. Invest Ophthalmol Vis Sci. 2008 Oct; 49(10):4263-8.
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Anand BS, Hill JM, Dey S, Maruyama K, Bhattacharjee PS, Myles ME, Nashed YE, Mitra AK. In vivo antiviral efficacy of a dipeptide acyclovir prodrug, val-val-acyclovir, against HSV-1 epithelial and stromal keratitis in the rabbit eye model. Invest Ophthalmol Vis Sci. 2003 Jun; 44(6):2529-34.