Subacute Sclerosing Panencephalitis
"Subacute Sclerosing Panencephalitis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)
Descriptor ID |
D013344
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MeSH Number(s) |
C02.182.525.600 C02.290.700 C02.782.580.600.500.500.800 C02.839.862 C10.228.140.430.520.750.600 C10.228.228.245.340.600 C10.228.228.399.750.600
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Concept/Terms |
Subacute Sclerosing Panencephalitis- Subacute Sclerosing Panencephalitis
- Sclerosing Panencephalitis, Subacute
- Panencephalitides, Subacute Sclerosing
- Sclerosing Panencephalitides, Subacute
- Subacute Sclerosing Panencephalitides
- Panencephalitis, Subacute Sclerosing
- Leukoencephalitis, Van Bogaert's
- Leukoencephalitis, Van Bogaert
- Leukoencephalitis, Van Bogaerts
- Inclusion Body Encephalitis, Measles
- Sclerosing Leukoencephalitis, Subacute
- Leukoencephalitides, Subacute Sclerosing
- Sclerosing Leukoencephalitides, Subacute
- Subacute Sclerosing Leukoencephalitides
- Subacute Sclerosing Leukoencephalitis
- Leukoencephalitis, Subacute Sclerosing
- Measles Inclusion Body Encephalitis
- Encephaltis, Inclusion Body, Measles
- SSPE
- Van Bogaert's Leukoencephalitis
- Van Bogaert Leukoencephalitis
- Van Bogaerts Leukoencephalitis
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Below are MeSH descriptors whose meaning is more general than "Subacute Sclerosing Panencephalitis".
Below are MeSH descriptors whose meaning is more specific than "Subacute Sclerosing Panencephalitis".
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Below are the most recent publications written about "Subacute Sclerosing Panencephalitis" by people in Profiles.
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Tabaton M, Mandybur TI, Perry G, Onorato M, Autilio-Gambetti L, Gambetti P. The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition. Ann Neurol. 1989 Dec; 26(6):771-8.