"Scrapie" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fatal disease of the nervous system in sheep and goats, characterized by pruritus, debility, and locomotor incoordination. It is caused by proteinaceous infectious particles called PRIONS.
| Descriptor ID |
D012608
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| MeSH Number(s) |
C10.228.228.800.717 C10.574.843.850 C22.836.799
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Scrapie".
Below are MeSH descriptors whose meaning is more specific than "Scrapie".
This graph shows the total number of publications written about "Scrapie" by people in this website by year, and whether "Scrapie" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Scrapie" by people in Profiles.
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Bastian FO, Fermin CD. Slow virus disease: deciphering conflicting data on the transmissible spongiform encephalopathies (TSE) also called prion diseases. Microsc Res Tech. 2005 Nov; 68(3-4):239-46.
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Kang SC, Brown DR, Whiteman M, Li R, Pan T, Perry G, Wisniewski T, Sy MS, Wong BS. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice. J Pathol. 2004 May; 203(1):603-8.
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Oldstone MB, Race R, Thomas D, Lewicki H, Homann D, Smelt S, Holz A, Koni P, Lo D, Chesebro B, Flavell R. Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: evidence against dendritic cell involvement in neuroinvasion. J Virol. 2002 May; 76(9):4357-63.
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Liberski PP, Yanagihara R, Wells GA, Gajdusek DC. Bovine spongiform encephalopathy in cattle mimics ultrastructurally experimental scrapie and Creutzfeldt-Jakob disease in rodents. Neuropatol Pol. 1993; 31(1-2):1-16.
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Guiroy DC, Williams ES, Song KJ, Yanagihara R, Gajdusek DC. Fibrils in brain of Rocky Mountain elk with chronic wasting disease contain scrapie amyloid. Acta Neuropathol. 1993; 86(1):77-80.
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Liberski PP, Yanagihara R, Wells GA, Gibbs CJ, Gajdusek DC. Ultrastructural pathology of axons and myelin in experimental scrapie in hamsters and bovine spongiform encephalopathy in cattle and a comparison with the panencephalopathic type of Creutzfeldt-Jakob disease. J Comp Pathol. 1992 May; 106(4):383-98.
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Liberski PP, Yanagihara R, Wells GA, Gibbs CJ, Gajdusek DC. Comparative ultrastructural neuropathology of naturally occurring bovine spongiform encephalopathy and experimentally induced scrapie and Creutzfeldt-Jakob disease. J Comp Pathol. 1992 May; 106(4):361-81.
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Liberski PP, Yanagihara R, Gibbs CJ, Gajdusek DC. Neuronal autophagic vacuoles in experimental scrapie and Creutzfeldt-Jakob disease. Acta Neuropathol. 1992; 83(2):134-9.
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Guiroy DC, Williams ES, Yanagihara R, Gajdusek DC. Topographic distribution of scrapie amyloid-immunoreactive plaques in chronic wasting disease in captive mule deer (Odocoileus hemionus hemionus). Acta Neuropathol. 1991; 81(5):475-8.
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Liberski PP, Yanagihara R, Gibbs CJ, Gajdusek DC. Appearance of tubulovesicular structures in experimental Creutzfeldt-Jakob disease and scrapie precedes the onset of clinical disease. Acta Neuropathol. 1990; 79(4):349-54.