"Kuru" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A prion disease found exclusively among the Fore linguistic group natives of the highlands of NEW GUINEA. The illness is primarily restricted to adult females and children of both sexes. It is marked by the subacute onset of tremor and ataxia followed by motor weakness and incontinence. Death occurs within 3-6 months of disease onset. The condition is associated with ritual cannibalism, and has become rare since this practice has been discontinued. Pathologic features include a noninflammatory loss of neurons that is most prominent in the cerebellum, glial proliferation, and amyloid plaques. (From Adams et al., Principles of Neurology, 6th ed, p773)
Descriptor ID |
D007729
|
MeSH Number(s) |
C10.228.228.800.435 C10.574.843.625
|
Concept/Terms |
Kuru- Kuru
- Encephalopathy, Kuru
- Kuru Encephalopathy
|
Below are MeSH descriptors whose meaning is more general than "Kuru".
Below are MeSH descriptors whose meaning is more specific than "Kuru".
This graph shows the total number of publications written about "Kuru" by people in this website by year, and whether "Kuru" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1996 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kuru" by people in Profiles.
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Liberski PP, Yanagihara R, Brown P, Kordek R, Kloszewska I, Bratosiewicz J, Gajdusek DC. Microwave treatment enhances the immunostaining of amyloid deposits in both the transmissible and non-transmissible brain amyloidoses. Neurodegeneration. 1996 Mar; 5(1):95-9.
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Biernat W, Liberski PP, Guiroy DC, Yanagihara R, Gajdusek DC. Proliferating cell nuclear antigen immunohistochemistry in astrocytes in experimental Creutzfeldt-Jakob disease and in human kuru, Creutzfeldt-Jakob disease and Gerstmann-Str?ussler-Scheinker syndrome. Neurodegeneration. 1995 Jun; 4(2):195-201.
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Guiroy DC, Yanagihara R, Gajdusek DC. Localization of amyloidogenic proteins and sulfated glycosaminoglycans in nontransmissible and transmissible cerebral amyloidoses. Acta Neuropathol. 1991; 82(2):87-92.
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Yanagihara RT, Asher DM, Gibbs CJ, Gajdusek DC. Attempts to establish cell cultures infected with the viruses of subacute spongiform encephalopathies. Proc Soc Exp Biol Med. 1980 Nov; 165(2):298-305.