Rats, Zucker

"Rats, Zucker" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Two populations of Zucker rats have been cited in research--the "fatty" or obese and the lean. The "fatty" rat (Rattus norvegicus) appeared as a spontaneous mutant. The obese condition appears to be due to a single recessive gene.

Descriptor ID	D011924
MeSH Number(s)	B01.050.150.900.649.313.992.635.505.700.550.700
Concept/Terms	Rats, Zucker Rats, Zucker Zucker Rats

Below are MeSH descriptors whose meaning is more general than "Rats, Zucker".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Rats [B01.050.150.900.649.313.992.635.505.700]
Rats, Mutant Strains [B01.050.150.900.649.313.992.635.505.700.550]
Rats, Zucker [B01.050.150.900.649.313.992.635.505.700.550.700]

Below are MeSH descriptors whose meaning is related to "Rats, Zucker".

Below are MeSH descriptors whose meaning is more specific than "Rats, Zucker".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Rats, Zucker" by people in this website by year, and whether "Rats, Zucker" was a major or minor topic of these publications.

Bar chart showing 20 publications over 16 distinct years, with a maximum of 2 publications in 2009 and 2017 and 2018 and 2019

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2000	1	1
2003	1	1
2006	1	1
2007	1	1
2008	1	1
2009	2	2
2010	1	1
2011	1	1
2014	1	1
2015	1	1
2016	1	1
2017	2	2
2018	2	2
2019	2	2
2020	1	1
2021	1	1

Below are the most recent publications written about "Rats, Zucker" by people in Profiles.

Baldelomar EJ, Charlton JR, Keilhoz S, Kohn B, Wilson LD, Xiong LI, Garfinkel A, Bennett KM. Measuring nephron number in the healthy and diabetic rat kidney in vivo using MRI without contrast agents. Am J Physiol Renal Physiol. 2026 Jun 01; 330(6):F643-F652.

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Thakur V, Alcoreza N, Delgado M, Joddar B, Chattopadhyay M. Cardioprotective Effect of Glycyrrhizin on Myocardial Remodeling in Diabetic Rats. Biomolecules. 2021 04 13; 11(4).

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Kovanecz I, Gelfand R, Sharifzad S, Ohanian A, DeCastro WB, Cooper C, Lin G, Lue T, Gonzalez-Cadavid NF. Evaluation of the In Vitro Damage Caused by Lipid Factors on Stem Cells from a Female Rat Model of Type 2 Diabetes/Obesity and Stress Urinary Incontinence. Int J Mol Sci. 2020 Jul 17; 21(14).

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Kovanecz I, Gelfand R, Lin G, Sharifzad S, Ohanian A, Ricks R, Lue T, Gonzalez-Cadavid NF. Stem Cells from a Female Rat Model of Type 2 Diabetes/Obesity and Stress Urinary Incontinence Are Damaged by In Vitro Exposure to its Dyslipidemic Serum, Predicting Inadequate Repair Capacity In Vivo. Int J Mol Sci. 2019 Aug 19; 20(16).

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Zhao X, Chen X, Zhang Y, George J, Cobbs A, Wang G, Li L, Emmett N. Kidney Injury Molecule-1 Is Upregulated in Renal Lipotoxicity and Mediates Palmitate-Induced Tubular Cell Injury and Inflammatory Response. Int J Mol Sci. 2019 Jul 11; 20(14).

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Masouminia M, Gelfand R, Kovanecz I, Vernet D, Tsao J, Salas R, Castro K, Loni L, Rajfer J, Gonzalez-Cadavid NF. Dyslipidemia Is a Major Factor in Stem Cell Damage Induced by Uncontrolled Long-Term Type 2 Diabetes and Obesity in the Rat, as Suggested by the Effects on Stem Cell Culture. J Sex Med. 2018 12; 15(12):1678-1697.

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Zhao X, Chen X, Chima A, Zhang Y, George J, Cobbs A, Emmett N. Albumin induces CD44 expression in glomerular parietal epithelial cells by activating extracellular signal-regulated kinase 1/2 pathway. J Cell Physiol. 2019 05; 234(5):7224-7235.

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Nurunnabi M, Lee SA, Revuri V, Hwang YH, Kang SH, Lee M, Cho S, Cho KJ, Byun Y, Bae YH, Lee DY, Lee YK. Oral delivery of a therapeutic gene encoding glucagon-like peptide 1 to treat high fat diet-induced diabetes. J Control Release. 2017 Dec 28; 268:305-313.

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Chen X, Cobbs A, George J, Chima A, Tuyishime F, Zhao X. Endocytosis of Albumin Induces Matrix Metalloproteinase-9 by Activating the ERK Signaling Pathway in Renal Tubule Epithelial Cells. Int J Mol Sci. 2017 Aug 12; 18(8).

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Kovanecz I, Vernet D, Masouminia M, Gelfand R, Loni L, Aboagye J, Tsao J, Rajfer J, Gonzalez-Cadavid NF. Implanted Muscle-Derived Stem Cells Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes, but Their Repair Capacity Is Impaired by Their Prior Exposure to the Diabetic Milieu. J Sex Med. 2016 05; 13(5):786-97.

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