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Kevin Bennett

Title
Faculty RankAssistant Professor
InstitutionUniversity of Hawaii
DepartmentBiology
AddressSchool of Life Sciences
University of Hawaii at Mānoa
1800 East-West Road
Honolulu HI
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    Collapse Research 
    Collapse research activities and funding
    R21DK091722     (BENNETT, KEVIN M.)Sep 20, 2012 - Jul 31, 2016
    NIH
    MRI Techniques to Measure Whole-Kidney Nephron
    Role: Principal Investigator
    R01DK111861     (CHARLTON, JENNIFER R)Aug 1, 2017 - Jul 1, 2021
    NIH
    Comprehensive MRI-based evaluation of human renal microstructure
    Role: Co-Principal Investigator
    R01DK110622     (BENNETT, KEVIN M)Sep 15, 2017 - Aug 31, 2021
    NIH
    Noninvasive MRI techniques to detect pathology in murine models of renal disease
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Baldelomar EJ, Morozov D, Wilson LD, Eldeniz C, An H, Charlton JR, Bauer AQ, Keilholz SD, Hulbert ML, Bennett KM. Resting-state MRI reveals spontaneous physiological fluctuations in the kidney and tracks diabetic nephropathy in rats. Am J Physiol Renal Physiol. 2024 Jul 01; 327(1):F113-F127. PMID: 38660712.
      Citations:    Fields:    Translation:HumansAnimals
    2. Li T, Xu Y, Wu T, Charlton JR, Bennett KM, Al-Hindawi F. BlobCUT: A Contrastive Learning Method to Support Small Blob Detection in Medical Imaging. Bioengineering (Basel). 2023 Nov 29; 10(12). PMID: 38135963.
      Citations:    
    3. Charlton JR, Li T, Wu T, deRonde K, Xu Y, Baldelomar EJ, Bennett KM. Use of novel structural features to identify urinary biomarkers during acute kidney injury that predict progression to chronic kidney disease. BMC Nephrol. 2023 06 19; 24(1):178. PMID: 37331957.
      Citations:    Fields:    Translation:Animals
    4. Baldelomar EJ, Emoto KC, Jordan MVC, Charlton JR, Reichert DE, Parvin N, Yokono C, Hann BD, Bennett KM. Synthesis and Expression of a Targeted, Ferritin-Based Tracer for PET Imaging of Kidney Glomeruli. Methods Mol Biol. 2023; 2664:201-213. PMID: 37423992.
      Citations:    Fields:    Translation:AnimalsCells
    5. Baldelomar EJ, Charlton JR, Bennett KM. Mapping single-nephron filtration in the isolated, perfused rat kidney using magnetic resonance imaging. Am J Physiol Renal Physiol. 2022 11 01; 323(5):F602-F611. PMID: 36049066.
      Citations: 1     Fields:    Translation:Animals
    6. Bennett KM, Baldelomar EJ, Charlton JR. Delivering on the potential of measuring nephron number in the clinic. Nat Rev Nephrol. 2022 05; 18(5):271-272. PMID: 35264770.
      Citations: 3     Fields:    Translation:Humans
    7. Morozov D, Parvin N, Conaway M, Oxley G, Baldelomar EJ, Cwiek A, deRonde K, Beeman SC, Charlton JR, Bennett KM. Estimating Nephron Number from Biopsies: Impact on Clinical Studies. J Am Soc Nephrol. 2022 01; 33(1):39-48. PMID: 34758983.
      Citations: 1     Fields:    Translation:Humans
    8. Cwiek A, Suzuki M, deRonde K, Conaway M, Bennett KM, El Dahr S, Reidy KJ, Charlton JR. Premature differentiation of nephron progenitor cell and dysregulation of gene pathways critical to kidney development in a model of preterm birth. Sci Rep. 2021 11 04; 11(1):21667. PMID: 34737344.
      Citations: 5     Fields:    Translation:AnimalsCells
    9. Xu Y, Wu T, Charlton JR, Gao F, Bennett KM. Small Blob Detector Using Bi-Threshold Constrained Adaptive Scales. IEEE Trans Biomed Eng. 2021 09; 68(9):2654-2665. PMID: 33347401.
      Citations: 2     Fields:    Translation:HumansAnimals
    10. Charlton JR, Xu Y, Parvin N, Wu T, Gao F, Baldelomar EJ, Morozov D, Beeman SC, Derakhshan J, Bennett KM. Image analysis techniques to map pyramids, pyramid structure, glomerular distribution, and pathology in the intact human kidney from 3-D MRI. Am J Physiol Renal Physiol. 2021 09 01; 321(3):F293-F304. PMID: 34282957.
      Citations: 3     Fields:    Translation:Humans
    11. Morozov D, Parvin N, Charlton JR, Bennett KM. Mapping kidney tubule diameter ex vivo by diffusion MRI. Am J Physiol Renal Physiol. 2021 05 01; 320(5):F934-F946. PMID: 33719573.
      Citations: 1     Fields:    Translation:HumansAnimals
    12. Pedersen M, Irrera P, Dastr? W, Z?llner FG, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR, Longo DL. Dynamic Contrast Enhancement (DCE) MRI-Derived Renal Perfusion and Filtration: Basic Concepts. Methods Mol Biol. 2021; 2216:205-227. PMID: 33476002.
      Citations: 2     Fields:    Translation:HumansAnimals
    13. Z?llner FG, Dastr? W, Irrera P, Longo DL, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR. Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration. Methods Mol Biol. 2021; 2216:637-653. PMID: 33476028.
      Citations:    Fields:    Translation:Animals
    14. Baldelomar EJ, Reichert DE, Shoghi KI, Beeman SC, Charlton JR, Strong L, Fettig N, Klaas A, Bennett KM. Mapping nephron mass in vivo using positron emission tomography. Am J Physiol Renal Physiol. 2021 02 01; 320(2):F183-F192. PMID: 33283644.
      Citations: 3     Fields:    Translation:HumansAnimals
    15. Charlton JR, Tan W, Daouk G, Teot L, Rosen S, Bennett KM, Cwiek A, Nam S, Emma F, Jouret F, Oliveira JP, Tranebj?rg L, Frykholm C, Mane S, Hildebrandt F, Srivastava T, Storm T, Christensen EI, Nielsen R. Beyond the tubule: pathological variants of LRP2, encoding the megalin receptor, result in glomerular loss and early progressive chronic kidney disease. Am J Physiol Renal Physiol. 2020 12 01; 319(6):F988-F999. PMID: 33103447.
      Citations: 8     Fields:    Translation:HumansAnimals
    16. Charlton JR, Xu Y, Wu T, deRonde KA, Hughes JL, Dutta S, Oxley GT, Cwiek A, Cathro HP, Charlton NP, Conaway MR, Baldelomar EJ, Parvin N, Bennett KM. Magnetic resonance imaging accurately tracks kidney pathology and heterogeneity in the transition from acute kidney injury to chronic kidney disease. Kidney Int. 2021 01; 99(1):173-185. PMID: 32916180.
      Citations: 10     Fields:    Translation:Animals
    17. Parvin N, Charlton JR, Baldelomar EJ, Derakhshan JJ, Bennett KM. Mapping vascular and glomerular pathology in a rabbit model of neonatal acute kidney injury using MRI. Anat Rec (Hoboken). 2020 10; 303(10):2716-2728. PMID: 32445514.
      Citations: 6     Fields:    Translation:Animals
    18. Charlton JR, Baldelomar EJ, Hyatt DM, Bennett KM. Nephron number and its determinants: a 2020 update. Pediatr Nephrol. 2021 04; 36(4):797-807. PMID: 32350665.
      Citations: 10     Fields:    Translation:Humans
    19. Xu Y, Wu T, Gao F, Charlton JR, Bennett KM. Improved small blob detection in 3D images using jointly constrained deep learning and Hessian analysis. Sci Rep. 2020 01 15; 10(1):326. PMID: 31941994.
      Citations: 9     Fields:    Translation:Humans
    20. Charlton JR, Baldelomar EJ, deRonde KA, Cathro HP, Charlton NP, Criswell SJ, Hyatt DM, Nam S, Pearl V, Bennett KM. Nephron loss detected by MRI following neonatal acute kidney injury in rabbits. Pediatr Res. 2020 06; 87(7):1185-1192. PMID: 31805577.
      Citations: 20     Fields:    Translation:Animals
    21. Baldelomar EJ, Charlton JR, deRonde KA, Bennett KM. In vivo measurements of kidney glomerular number and size in healthy and Os/+ mice using MRI. Am J Physiol Renal Physiol. 2019 10 01; 317(4):F865-F873. PMID: 31339774.
      Citations: 12     Fields:    Translation:Animals
    22. Selewski DT, Hyatt DM, Bennett KM, Charlton JR. Is acute kidney injury a harbinger for chronic kidney disease? Curr Opin Pediatr. 2018 04; 30(2):236-240. PMID: 29389682.
      Citations:    
    23. Baldelomar EJ, Charlton JR, Beeman SC, Bennett KM. Measuring rat kidney glomerular number and size in vivo with MRI. Am J Physiol Renal Physiol. 2018 03 01; 314(3):F399-F406. PMID: 29092847.
      Citations: 26     Fields:    Translation:Animals
    24. Xie L, Bennett KM, Liu C, Johnson GA, Zhang JL, Lee VS. MRI tools for assessment of microstructure and nephron function of the kidney. Am J Physiol Renal Physiol. 2016 12 01; 311(6):F1109-F1124. PMID: 27630064.
      Citations: 16     Fields:    Translation:HumansAnimals
    25. Wu T, Bennett KM. 3D small structure detection in medical image using texture analysis. Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug; 2016:6433-6436. PMID: 28269719.
      Citations: 1     Fields:    Translation:HumansAnimals
    26. Charlton JR, Pearl VM, Denotti AR, Lee JB, Swaminathan S, Scindia YM, Charlton NP, Baldelomar EJ, Beeman SC, Bennett KM. Biocompatibility of ferritin-based nanoparticles as targeted MRI contrast agents. Nanomedicine. 2016 08; 12(6):1735-45. PMID: 27071333.
      Citations: 17     Fields:    Translation:Animals
    27. Hann BD, Baldelomar EJ, Charlton JR, Bennett KM. Measuring the intrarenal distribution of glomerular volumes from histological sections. Am J Physiol Renal Physiol. 2016 06 01; 310(11):F1328-36. PMID: 26984953.
      Citations: 3     Fields:    Translation:Animals
    28. Baldelomar EJ, Charlton JR, Beeman SC, Hann BD, Cullen-McEwen L, Pearl VM, Bertram JF, Wu T, Zhang M, Bennett KM. Phenotyping by magnetic resonance imaging nondestructively measures glomerular number and volume distribution in mice with and without nephron reduction. Kidney Int. 2016 Feb; 89(2):498-505. PMID: 26535998.
      Citations: 39     Fields:    Translation:Animals
    29. Bennett KM, Beeman SC, Baldelomar EJ, Zhang M, Wu T, Hann BD, Bertram JF, Charlton JR. Use of Cationized Ferritin Nanoparticles to Measure Renal Glomerular Microstructure with MRI. Methods Mol Biol. 2016; 1397:67-79. PMID: 26676128.
      Citations: 5     Fields:    Translation:HumansAnimals
    30. Zhang M, Wu T, Beeman SC, Cullen-McEwen L, Bertram JF, Charlton JR, Baldelomar E, Bennett KM. Efficient Small Blob Detection Based on Local Convexity, Intensity and Shape Information. IEEE Trans Med Imaging. 2016 Apr; 35(4):1127-37. PMID: 26685229.
      Citations: 11     Fields:    Translation:HumansAnimals
    31. Bennett KM. MRI shines (radiofrequency) light on kidney physiology. Am J Physiol Renal Physiol. 2016 Jan 01; 310(1):F41-2. PMID: 26538445.
      Citations:    Fields:    Translation:Animals
    32. Zhang M, Wu T, Bennett KM. Small blob identification in medical images using regional features from optimum scale. IEEE Trans Biomed Eng. 2015 Apr; 62(4):1051-62. PMID: 25265624.
      Citations: 16     Fields:    Translation:Humans
    33. Qian C, Yu X, Pothayee N, Dodd S, Bouraoud N, Star R, Bennett K, Koretsky A. Live nephron imaging by MRI. Am J Physiol Renal Physiol. 2014 Nov 15; 307(10):F1162-8. PMID: 25186296.
      Citations: 16     Fields:    Translation:Animals
    34. Bennett KM, Jo J, Cabral H, Bakalova R, Aoki I. MR imaging techniques for nano-pathophysiology and theranostics. Adv Drug Deliv Rev. 2014 Jul; 74:75-94. PMID: 24787226.
      Citations: 12     Fields:    Translation:HumansAnimals
    35. Clavijo Jordan MV, Beeman SC, Baldelomar EJ, Bennett KM. Disruptive chemical doping in a ferritin-based iron oxide nanoparticle to decrease r2 and enhance detection with T1-weighted MRI. Contrast Media Mol Imaging. 2014 Sep-Oct; 9(5):323-32. PMID: 24764110.
      Citations: 17     Fields:    Translation:HumansAnimals
    36. Bertram JF, Cullen-McEwen LA, Egan GF, Gretz N, Baldelomar E, Beeman SC, Bennett KM. Why and how we determine nephron number. Pediatr Nephrol. 2014 Apr; 29(4):575-80. PMID: 24022365.
      Citations: 17     Fields:    Translation:HumansAnimals
    37. Beeman SC, Cullen-McEwen LA, Puelles VG, Zhang M, Wu T, Baldelomar EJ, Dowling J, Charlton JR, Forbes MS, Ng A, Wu QZ, Armitage JA, Egan GF, Bertram JF, Bennett KM. MRI-based glomerular morphology and pathology in whole human kidneys. Am J Physiol Renal Physiol. 2014 Jun 01; 306(11):F1381-90. PMID: 24647716.
      Citations: 56     Fields:    Translation:Humans
    38. Beeman SC, Mandarino LJ, Georges JF, Bennett KM. Cationized ferritin as a magnetic resonance imaging probe to detect microstructural changes in a rat model of non-alcoholic steatohepatitis. Magn Reson Med. 2013 Dec; 70(6):1728-38. PMID: 23390010.
      Citations: 8     Fields:    Translation:AnimalsCells
    39. Charlton JR, Beeman SC, Bennett KM. MRI-detectable nanoparticles: the potential role in the diagnosis of and therapy for chronic kidney disease. Adv Chronic Kidney Dis. 2013 Nov; 20(6):479-87. PMID: 24206600.
      Citations: 4     Fields:    Translation:Humans
    40. Bennett KM, Bertram JF, Beeman SC, Gretz N. The emerging role of MRI in quantitative renal glomerular morphology. Am J Physiol Renal Physiol. 2013 May 15; 304(10):F1252-7. PMID: 23515719.
      Citations: 23     Fields:    Translation:Humans
    41. Qian C, Yu X, Chen DY, Dodd S, Bouraoud N, Pothayee N, Chen Y, Beeman S, Bennett K, Murphy-Boesch J, Koretsky A. Wireless amplified nuclear MR detector (WAND) for high-spatial-resolution MR imaging of internal organs: preclinical demonstration in a rodent model. Radiology. 2013 Jul; 268(1):228-36. PMID: 23392428.
      Citations: 31     Fields:    Translation:Animals
    42. Beeman SC, Georges JF, Bennett KM. Toxicity, biodistribution, and ex vivo MRI detection of intravenously injected cationized ferritin. Magn Reson Med. 2013 Mar 01; 69(3):853-61. PMID: 22570266.
      Citations: 18     Fields:    Translation:Animals
    43. Clavijo-Jordan V, Kodibagkar VD, Beeman SC, Hann BD, Bennett KM. Principles and emerging applications of nanomagnetic materials in medicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012 Jul-Aug; 4(4):345-65. PMID: 22488879.
      Citations: 6     Fields:    Translation:HumansAnimals
    44. Beeman SC, Zhang M, Gubhaju L, Wu T, Bertram JF, Frakes DH, Cherry BR, Bennett KM. Measuring glomerular number and size in perfused kidneys using MRI. Am J Physiol Renal Physiol. 2011 Jun; 300(6):F1454-7. PMID: 21411479.
      Citations: 49     Fields:    Translation:Animals
    45. Jordan VC, Caplan MR, Bennett KM. Simplified synthesis and relaxometry of magnetoferritin for magnetic resonance imaging. Magn Reson Med. 2010 Nov; 64(5):1260-6. PMID: 20677230.
      Citations: 12     Fields:    Translation:Animals
    46. Colomb J, Louie K, Massia SP, Bennett KM. Self-degrading, MRI-detectable hydrogel sensors with picomolar target sensitivity. Magn Reson Med. 2010 Dec; 64(6):1792-9. PMID: 20648680.
      Citations: 6     Fields:    Translation:Animals
    47. Martirosyan NL, Bennett KM, Theodore N, Preul MC. Manganese-enhanced magnetic resonance imaging in experimental spinal cord injury: correlation between T1-weighted changes and Mn(2+) concentrations. Neurosurgery. 2010 Jan; 66(1):131-6. PMID: 20023543.
      Citations: 6     Fields:    Translation:Animals
    48. Bennett KM, Zhou H, Sumner JP, Dodd SJ, Bouraoud N, Doi K, Star RA, Koretsky AP. MRI of the basement membrane using charged nanoparticles as contrast agents. Magn Reson Med. 2008 Sep; 60(3):564-74. PMID: 18727041.
      Citations: 52     Fields:    Translation:AnimalsCells
    49. Bennett KM, Shapiro EM, Sotak CH, Koretsky AP. Controlled aggregation of ferritin to modulate MRI relaxivity. Biophys J. 2008 Jul; 95(1):342-51. PMID: 18326661.
      Citations: 21     Fields:    
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