Kidney Tubules, Proximal

"Kidney Tubules, Proximal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The renal tubule portion that extends from the BOWMAN CAPSULE in the KIDNEY CORTEX into the KIDNEY MEDULLA. The proximal tubule consists of a convoluted proximal segment in the cortex, and a distal straight segment descending into the medulla where it forms the U-shaped LOOP OF HENLE.

Descriptor ID	D007687
MeSH Number(s)	A05.810.453.736.560.570
Concept/Terms	Kidney Tubules, Proximal Kidney Tubules, Proximal Kidney Tubule, Proximal Proximal Kidney Tubules Tubule, Proximal Kidney Tubules, Proximal Kidney Proximal Renal Tubule Proximal Renal Tubules Renal Tubule, Proximal Renal Tubules, Proximal Tubule, Proximal Renal Tubules, Proximal Renal Proximal Kidney Tubule

Below are MeSH descriptors whose meaning is more general than "Kidney Tubules, Proximal".

Anatomy [A]
Urogenital System [A05]
Urinary Tract [A05.810]
Kidney [A05.810.453]
Nephrons [A05.810.453.736]
Kidney Tubules [A05.810.453.736.560]
Kidney Tubules, Proximal [A05.810.453.736.560.570]

Below are MeSH descriptors whose meaning is related to "Kidney Tubules, Proximal".

Below are MeSH descriptors whose meaning is more specific than "Kidney Tubules, Proximal".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Kidney Tubules, Proximal" by people in this website by year, and whether "Kidney Tubules, Proximal" was a major or minor topic of these publications.

Bar chart showing 27 publications over 17 distinct years, with a maximum of 3 publications in 2015 and 2019 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
2001	2	0	2
2002	1	1	2
2003	1	0	1
2004	1	0	1
2005	1	0	1
2006	1	0	1
2007	2	0	2
2011	1	0	1
2013	1	0	1
2015	2	1	3
2017	1	0	1
2019	3	0	3
2020	1	2	3
2021	1	0	1
2024	1	1	2
2025	1	0	1

Below are the most recent publications written about "Kidney Tubules, Proximal" by people in Profiles.

Battle D, Qiu X, Alex M, Rivers L, Hamilton JAG, Takayama S, Zhao X. Caki-1 Spheroids as a Renal Model for Studying Free Fatty Acid-Induced Lipotoxicity. Cells. 2025 02 27; 14(5).

View in: PubMed
Darshi M, Kugathasan L, Maity S, Sridhar VS, Fernandez R, Limonte CP, Grajeda BI, Saliba A, Zhang G, Drel VR, Kim JJ, Montellano R, Tumova J, Montemayor D, Wang Z, Liu JJ, Wang J, Perkins BA, Lytvyn Y, Natarajan L, Lim SC, Feldman H, Toto R, Sedor JR, Patel J, Waikar SS, Brown J, Osman Y, He J, Chen J, Reeves WB, de Boer IH, Roy S, Vallon V, Hallan S, Gelfond JA, Cherney DZ, Sharma K. Glycolytic lactate in diabetic kidney disease. JCI Insight. 2024 Jun 10; 9(11).

View in: PubMed
Feng Y, Sun Z, Fu J, Zhong F, Zhang W, Wei C, Chen A, Liu BC, He JC, Lee K. Podocyte-derived soluble RARRES1 drives kidney disease progression through direct podocyte and proximal tubular injury. Kidney Int. 2024 07; 106(1):50-66.

View in: PubMed
Cao JY, Wang B, Tang TT, Wen Y, Li ZL, Feng ST, Wu M, Liu D, Yin D, Ma KL, Tang RN, Wu QL, Lan HY, Lv LL, Liu BC. Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury. Theranostics. 2021; 11(11):5248-5266.

View in: PubMed
Han SJ, Williams RM, Kim M, Heller DA, D'Agati V, Schmidt-Supprian M, Lee HT. Renal proximal tubular NEMO plays a critical role in ischemic acute kidney injury. JCI Insight. 2020 09 17; 5(19).

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Nlandu-Khodo S, Osaki Y, Scarfe L, Yang H, Phillips-Mignemi M, Tonello J, Saito-Diaz K, Neelisetty S, Ivanova A, Huffstater T, McMahon R, Taketo MM, deCaestecker M, Kasinath B, Harris RC, Lee E, Gewin LS. Tubular ?-catenin and FoxO3 interactions protect in chronic kidney disease. JCI Insight. 2020 05 21; 5(10).

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Han SJ, Williams RM, D'Agati V, Jaimes EA, Heller DA, Lee HT. Selective nanoparticle-mediated targeting of renal tubular Toll-like receptor 9 attenuates ischemic acute kidney injury. Kidney Int. 2020 07; 98(1):76-87.

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Cobbs A, Chen X, Zhang Y, George J, Huang MB, Bond V, Thompson W, Zhao X. Saturated fatty acid stimulates production of extracellular vesicles by renal tubular epithelial cells. Mol Cell Biochem. 2019 Aug; 458(1-2):113-124.

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Wu M, Feng Y, Ye GX, Han YC, Wang SS, Ni HF, Wang FM, Gao M, Lv LL, Liu BC. Calcium-sensing receptor activation attenuates collagen expression in renal proximal tubular epithelial cells. Am J Physiol Renal Physiol. 2019 05 01; 316(5):F1006-F1015.

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Manolopoulou M, Matlock BK, Nlandu-Khodo S, Simmons AJ, Lau KS, Phillips-Mignemi M, Ivanova A, Alford CE, Flaherty DK, Gewin LS. Novel kidney dissociation protocol and image-based flow cytometry facilitate improved analysis of injured proximal tubules. Am J Physiol Renal Physiol. 2019 05 01; 316(5):F847-F855.

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