"Muscular Atrophy, Spinal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Descriptor ID |
D009134
|
| MeSH Number(s) |
C10.228.854.468 C10.574.562.500 C10.668.467.500
|
| Concept/Terms |
Muscular Atrophy, Spinal- Muscular Atrophy, Spinal
- Atrophy, Spinal Muscular
- Spinal Amyotrophy
- Amyotrophies, Spinal
- Amyotrophy, Spinal
- Spinal Amyotrophies
- Spinal Muscular Atrophy
Hereditary Motor Neuronopathy- Hereditary Motor Neuronopathy
- Hereditary Motor Neuronopathies
- Motor Neuronopathies, Hereditary
- Motor Neuronopathy, Hereditary
- Neuronopathies, Hereditary Motor
- Neuronopathy, Hereditary Motor
Scapuloperoneal Form of Spinal Muscular Atrophy- Scapuloperoneal Form of Spinal Muscular Atrophy
- Spinal Muscular Atrophy, Scapuloperoneal Form
- Spinal Muscular Atrophy, Scapuloperoneal
- Amyotrophy, Neurogenic Scapuloperoneal, New England Type
- Scapuloperoneal Spinal Muscular Atrophy
Progressive Muscular Atrophy- Progressive Muscular Atrophy
- Atrophies, Progressive Muscular
- Atrophy, Progressive Muscular
- Muscular Atrophies, Progressive
- Muscular Atrophy, Progressive
- Progressive Muscular Atrophies
- Progressive Myelopathic Muscular Atrophy
- Myelopathic Muscular Atrophy, Progressive
Bulbospinal Neuronopathy- Bulbospinal Neuronopathy
- Bulbospinal Neuronopathies
- Neuronopathies, Bulbospinal
- Neuronopathy, Bulbospinal
Myelopathic Muscular Atrophy- Myelopathic Muscular Atrophy
- Atrophy, Myelopathic Muscular
- Muscular Atrophy, Myelopathic
- Adult-Onset Spinal Muscular Atrophy
- Adult Onset Spinal Muscular Atrophy
- Muscular Atrophy, Adult Spinal
- Adult Spinal Muscular Atrophy
|
Below are MeSH descriptors whose meaning is more general than "Muscular Atrophy, Spinal".
Below are MeSH descriptors whose meaning is more specific than "Muscular Atrophy, Spinal".
This graph shows the total number of publications written about "Muscular Atrophy, Spinal" by people in this website by year, and whether "Muscular Atrophy, Spinal" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Muscular Atrophy, Spinal" by people in Profiles.
-
Cottam NC, Harrington MA, Schork PM, Sun J. No significant sex differences in incidence or phenotype for the SMN?7 mouse model of spinal muscular atrophy. Neuromuscul Disord. 2024 Apr; 37:13-22.
-
Cottam NC, Bamfo T, Harrington MA, Charvet CJ, Hekmatyar K, Tulin N, Sun J. Cerebellar structural, astrocytic, and neuronal abnormalities in the SMN?7 mouse model of spinal muscular atrophy. Brain Pathol. 2023 09; 33(5):e13162.
-
Sun J, Harrington MA, Porter B. Sex Difference in Spinal Muscular Atrophy Patients - are Males More Vulnerable? J Neuromuscul Dis. 2023; 10(5):847-867.
-
Tharaneetharan A, Cole M, Norman B, Romero NC, Wooltorton JRA, Harrington MA, Sun J. Functional Abnormalities of Cerebellum and Motor Cortex in Spinal Muscular Atrophy Mice. Neuroscience. 2021 01 01; 452:78-97.
-
Horga A, Tomaselli PJ, Gonzalez MA, Laur? M, Muntoni F, Manzur AY, Hanna MG, Blake JC, Houlden H, Z?chner S, Reilly MM. SIGMAR1 mutation associated with autosomal recessive Silver-like syndrome. Neurology. 2016 Oct 11; 87(15):1607-1612.
-
Dimitriadi M, Sleigh JN, Walker A, Chang HC, Sen A, Kalloo G, Harris J, Barsby T, Walsh MB, Satterlee JS, Li C, Van Vactor D, Artavanis-Tsakonas S, Hart AC. Conserved genes act as modifiers of invertebrate SMN loss of function defects. PLoS Genet. 2010 Oct 28; 6(10):e1001172.
-
Zhang H, Robinson N, Wu C, Wang W, Harrington MA. Electrophysiological properties of motor neurons in a mouse model of severe spinal muscular atrophy: in vitro versus in vivo development. PLoS One. 2010 Jul 21; 5(7):e11696.