Stable inhibition of specific estrogen receptor a (ERa) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells.

Huderson BP, Duplessis TT, Williams CC, Seger HC, Marsden CG, Pouey KJ, Hill SM, Rowan BG. Stable inhibition of specific estrogen receptor a (ERa) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells. Endocrinology. 2012 Sep; 153(9):4144-59.

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subject areas

Breast Neoplasms
Cell Line, Tumor
Cell Movement
Cell Proliferation
Estrogen Receptor alpha
Female
Gene Expression Regulation, Neoplastic
Humans
Phosphorylation
RNA, Small Interfering
Signal Transduction

authors with profiles

Christopher C. Williams

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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