"Lipid A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lipid A is the biologically active component of lipopolysaccharides. It shows strong endotoxic activity and exhibits immunogenic properties.
| Descriptor ID |
D008050
|
| MeSH Number(s) |
D09.698.718.450.500 D10.494.500 D23.050.161.616.525.500 D23.946.123.329.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Lipid A".
Below are MeSH descriptors whose meaning is more specific than "Lipid A".
This graph shows the total number of publications written about "Lipid A" by people in this website by year, and whether "Lipid A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipid A" by people in Profiles.
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Hankins JV, Madsen JA, Giles DK, Childers BM, Klose KE, Brodbelt JS, Trent MS. Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy-acyltransferase and its role in innate immune recognition. Mol Microbiol. 2011 Sep; 81(5):1313-29.
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Hui G, Choe D, Hashimoto C. Biological activities of anti-merozoite surface protein-1 antibodies induced by adjuvant-assisted immunizations in mice with different immune gene knockouts. Clin Vaccine Immunol. 2008 Aug; 15(8):1145-50.
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Albers U, Tiaden A, Spirig T, Al Alam D, Goyert SM, Gangloff SC, Hilbi H. Expression of Legionella pneumophila paralogous lipid A biosynthesis genes under different growth conditions. Microbiology (Reading). 2007 Nov; 153(Pt 11):3817-3829.
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Schild S, Lamprecht AK, Fourestier C, Lauriano CM, Klose KE, Reidl J. Characterizing lipopolysaccharide and core lipid A mutant O1 and O139 Vibrio cholerae strains for adherence properties on mucus-producing cell line HT29-Rev MTX and virulence in mice. Int J Med Microbiol. 2005 Aug; 295(4):243-51.
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Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT. Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. J Biol Chem. 2004 Dec 24; 279(52):54405-15.
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Campos MA, Rosinha GM, Almeida IC, Salgueiro XS, Jarvis BW, Splitter GA, Qureshi N, Bruna-Romero O, Gazzinelli RT, Oliveira SC. Role of Toll-like receptor 4 in induction of cell-mediated immunity and resistance to Brucella abortus infection in mice. Infect Immun. 2004 Jan; 72(1):176-86.
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Hui GS, Tam LQ, Chang SP, Case SE, Hashiro C, Siddiqui WA, Shiba T, Kusumoto S, Kotani S. Synthetic low-toxicity muramyl dipeptide and monophosphoryl lipid A replace Freund complete adjuvant in inducing growth-inhibitory antibodies to the Plasmodium falciparum major merozoite surface protein, gp195. Infect Immun. 1991 May; 59(5):1585-91.
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Mitchell MS, Harel W, Kempf RA, Hu E, Kan-Mitchell J, Boswell WD, Dean G, Stevenson L. Active-specific immunotherapy for melanoma. J Clin Oncol. 1990 May; 8(5):856-69.