"Immunoglobulin J-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 15 kD "joining" peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.
| Descriptor ID |
D007144
|
| MeSH Number(s) |
D12.776.124.486.485.705.625 D12.776.124.790.651.705.625 D12.776.377.715.548.705.625
|
| Concept/Terms |
Immunoglobulin J-Chains- Immunoglobulin J-Chains
- Immunoglobulin J Chains
- J-Chains, Immunoglobulin
- J Chains, Immunoglobulin
- Immunoglobulin J-Peptide
- Immunoglobulin J Peptide
- J-Peptide, Immunoglobulin
- Ig J-Peptide
- Ig J Peptide
- J-Peptide, Ig
- Immunoglobulin J Polypeptide
- J Polypeptide, Immunoglobulin
- Polypeptide, Immunoglobulin J
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin J-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin J-Chains".
This graph shows the total number of publications written about "Immunoglobulin J-Chains" by people in this website by year, and whether "Immunoglobulin J-Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin J-Chains" by people in Profiles.
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Radomska HS, Shen CP, Kadesch T, Eckhardt LA. Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma x T cell hybrids. Immunity. 1994 Nov; 1(8):623-34.
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Bangs LA, Sanz IE, Teale JM. Comparison of D, JH, and junctional diversity in the fetal, adult, and aged B cell repertoires. J Immunol. 1991 Mar 15; 146(6):1996-2004.
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Hope TJ, Aguilera RJ, Minie ME, Sakano H. Endonucleolytic activity that cleaves immunoglobulin recombination sequences. Science. 1986 Mar 07; 231(4742):1141-5.