"Hybridomas" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells artificially created by fusion of activated lymphocytes with neoplastic cells. The resulting hybrid cells are cloned and produce pure MONOCLONAL ANTIBODIES or T-cell products, identical to those produced by the immunologically competent parent cell.
| Descriptor ID |
D006825
|
| MeSH Number(s) |
A11.251.353.485 A11.251.600.485
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hybridomas".
Below are MeSH descriptors whose meaning is more specific than "Hybridomas".
This graph shows the total number of publications written about "Hybridomas" by people in this website by year, and whether "Hybridomas" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hybridomas" by people in Profiles.
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Xu C, Ou J, Cui Y, Wang L, Lv C, Liu K, Wang B, Xu T, Li QX, Liu S. Development of a monoclonal antibody-based enzyme-linked immunosorbent assay for tetrabromobisphenol A. Monoclon Antib Immunodiagn Immunother. 2013 Apr; 32(2):113-8.
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Dias BR, Rodrigues EG, Nimrichter L, Nakayasu ES, Almeida IC, Travassos LR. Identification of iGb3 and iGb4 in melanoma B16F10-Nex2 cells and the iNKT cell-mediated antitumor effect of dendritic cells primed with iGb3. Mol Cancer. 2009 Dec 07; 8:116.
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Zhao J, Yi GX, He SP, Wang BM, Yu CX, Li G, Zhai ZX, Li ZH, Li QX. Development of a monoclonal antibody-based enzyme-linked immunosorbent assay for the herbicide chlorimuron-ethyl. J Agric Food Chem. 2006 Jul 12; 54(14):4948-53.
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Hoffmann PR, Kench JA, Vondracek A, Kruk E, Daleke DL, Jordan M, Marrack P, Henson PM, Fadok VA. Interaction between phosphatidylserine and the phosphatidylserine receptor inhibits immune responses in vivo. J Immunol. 2005 Feb 01; 174(3):1393-404.
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Thomas TP, Patri AK, Myc A, Myaing MT, Ye JY, Norris TB, Baker JR. In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles. Biomacromolecules. 2004 Nov-Dec; 5(6):2269-74.
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Salas M, Eckhardt LA. Critical role for the Oct-2/OCA-B partnership in Ig-secreting cells. J Immunol. 2003 Dec 15; 171(12):6589-98.
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Fan L, Busser BW, Lifsted TQ, Oukka M, Lo D, Laufer TM. Antigen presentation by keratinocytes directs autoimmune skin disease. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3386-91.
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Blake RC, Delehanty JB, Khosraviani M, Yu H, Jones RM, Blake DA. Allosteric binding properties of a monoclonal antibody and its Fab fragment. Biochemistry. 2003 Jan 21; 42(2):497-508.
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Yoshida S, Kobayashi T, Matsuoka H, Seki C, Gosnell WL, Chang SP, Ishii A. T-cell activation and cytokine production via a bispecific single-chain antibody fragment targeted to blood-stage malaria parasites. Blood. 2003 Mar 15; 101(6):2300-6.
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Turner CW, Lima MF, Villalta F. Trypanosoma cruzi uses a 45-kDa mucin for adhesion to mammalian cells. Biochem Biophys Res Commun. 2002 Jan 11; 290(1):29-34.