"Ferrochelatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA.
Descriptor ID |
D005294
|
MeSH Number(s) |
D08.811.520.500 D12.776.157.427.374.375.957 D12.776.556.579.374.375.617 D12.776.575.562
|
Concept/Terms |
Ferrochelatase- Ferrochelatase
- Protoheme Ferro-Lyase
- Ferro-Lyase, Protoheme
- Protoheme Ferro Lyase
- Heme Synthetase
- Synthetase, Heme
- Porphyrin-Metal Chelatase
- Chelatase, Porphyrin-Metal
- Porphyrin Metal Chelatase
|
Below are MeSH descriptors whose meaning is more general than "Ferrochelatase".
Below are MeSH descriptors whose meaning is more specific than "Ferrochelatase".
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