"Amifostine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
| Descriptor ID |
D004999
|
| MeSH Number(s) |
D02.705.400.625.050 D02.705.539.345.050 D02.886.300.692.050
|
| Concept/Terms |
Amifostine- Amifostine
- Amifostine Trihydrate
- Trihydrate, Amifostine
- APAETP
|
Below are MeSH descriptors whose meaning is more general than "Amifostine".
Below are MeSH descriptors whose meaning is more specific than "Amifostine".
This graph shows the total number of publications written about "Amifostine" by people in this website by year, and whether "Amifostine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
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Below are the most recent publications written about "Amifostine" by people in Profiles.
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Praetorius NP, Mandal TK. Alternate delivery route for amifostine as a radio-/chemo-protecting agent. J Pharm Pharmacol. 2008 Jul; 60(7):809-15.
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Pamujula S, Graves RA, Moiseyev R, Bostanian LA, Kishore V, Mandal TK. Preparation of polylactide-co-glycolide and chitosan hybrid microcapsules of amifostine using coaxial ultrasonic atomizer with solvent evaporation. J Pharm Pharmacol. 2008 Mar; 60(3):283-9.
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Pamujula S, Kishore V, Rider B, Fermin CD, Graves RA, Agrawal KC, Mandal TK. Radioprotection in mice following oral delivery of amifostine nanoparticles. Int J Radiat Biol. 2005 Mar; 81(3):251-7.
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Pamujula S, Graves RA, Freeman T, Srinivasan V, Bostanian LA, Kishore V, Mandal TK. Oral delivery of spray dried PLGA/amifostine nanoparticles. J Pharm Pharmacol. 2004 Sep; 56(9):1119-25.
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Pamujula S, Graves RA, Kishore V, Mandal TK. Preparation and in vitro characterization of amifostine biodegradable microcapsules. Eur J Pharm Biopharm. 2004 Mar; 57(2):213-8.
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Mandal TK, Bostanian LA, Graves RA, Chapman SR, Womack I. Development of biodegradable microcapsules as carrier for oral controlled delivery of amifostine. Drug Dev Ind Pharm. 2002 Mar; 28(3):339-44.