"Epoxide Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze reversibly the formation of an epoxide or arene oxide from a glycol or aromatic diol, respectively.
| Descriptor ID |
D004851
|
| MeSH Number(s) |
D08.811.277.340
|
| Concept/Terms |
Epoxide Hydrolases- Epoxide Hydrolases
- Hydrolases, Epoxide
- Epoxide Hydratases
- Hydratases, Epoxide
- Epoxide Hydrases
- Hydrases, Epoxide
9,10-Epoxypalmitic Acid Hydrase- 9,10-Epoxypalmitic Acid Hydrase
- 9,10 Epoxypalmitic Acid Hydrase
- Acid Hydrase, 9,10-Epoxypalmitic
- Hydrase, 9,10-Epoxypalmitic Acid
|
Below are MeSH descriptors whose meaning is more general than "Epoxide Hydrolases".
Below are MeSH descriptors whose meaning is more specific than "Epoxide Hydrolases".
This graph shows the total number of publications written about "Epoxide Hydrolases" by people in this website by year, and whether "Epoxide Hydrolases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Epoxide Hydrolases" by people in Profiles.
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Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX. 1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells. ACS Chem Neurosci. 2019 09 18; 10(9):4018-4030.
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Brown JR, North EJ, Hurdle JG, Morisseau C, Scarborough JS, Sun D, Kordul?kov? J, Scherman MS, Jones V, Grzegorzewicz A, Crew RM, Jackson M, McNeil MR, Lee RE. The structure-activity relationship of urea derivatives as anti-tuberculosis agents. Bioorg Med Chem. 2011 Sep 15; 19(18):5585-95.
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Rawal S, Morisseau C, Hammock BD, Shivachar AC. Differential subcellular distribution and colocalization of the microsomal and soluble epoxide hydrolases in cultured neonatal rat brain cortical astrocytes. J Neurosci Res. 2009 Jan; 87(1):218-27.
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Sun Z, Sood S, Li N, Ramji D, Yang P, Newman RA, Yang CS, Chen X. Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors. Carcinogenesis. 2006 Sep; 27(9):1902-8.
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Chen X, Wang S, Wu N, Yang CS. Leukotriene A4 hydrolase as a target for cancer prevention and therapy. Curr Cancer Drug Targets. 2004 May; 4(3):267-83.
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Howard CB, Stevens J, Izevbigie EB, Walker A, McDaniel O. Time and dose-dependent modulation of phase 1 and phase 2 gene expression in response to treatment of MCF-7 cells with a natural anti-cancer agent. Cell Mol Biol (Noisy-le-grand). 2003 Nov; 49(7):1057-65.
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Chen X, Li N, Wang S, Wu N, Hong J, Jiao X, Krasna MJ, Beer DG, Yang CS. Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. J Natl Cancer Inst. 2003 Jul 16; 95(14):1053-61.