"Dynorphins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.
Descriptor ID |
D004399
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MeSH Number(s) |
D12.644.400.575.180 D12.776.631.650.575.180
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Dynorphins".
Below are MeSH descriptors whose meaning is more specific than "Dynorphins".
This graph shows the total number of publications written about "Dynorphins" by people in this website by year, and whether "Dynorphins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1995 | 0 | 1 | 1 |
1997 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2008 | 1 | 1 | 2 |
2009 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dynorphins" by people in Profiles.
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Nguyen K, Tseng A, Marquez P, Hamid A, Lutfy K. The role of endogenous dynorphin in ethanol-induced state-dependent CPP. Behav Brain Res. 2012 Feb 01; 227(1):58-63.
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Parikh D, Hamid A, Friedman TC, Nguyen K, Tseng A, Marquez P, Lutfy K. Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration. Eur J Pharmacol. 2011 Jan 15; 650(2-3):563-7.
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Zhan S, Zhao H, J White A, Minami M, Pignataro G, Yang T, Zhu X, Lan J, Xiong Z, Steiner DF, Simon RP, Zhou A. Defective neuropeptide processing and ischemic brain injury: a study on proprotein convertase 2 and its substrate neuropeptide in ischemic brains. J Cereb Blood Flow Metab. 2009 Apr; 29(4):698-706.
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Torres-Reveron A, Khalid S, Williams TJ, Waters EM, Jacome L, Luine VN, Drake CT, McEwen BS, Milner TA. Hippocampal dynorphin immunoreactivity increases in response to gonadal steroids and is positioned for direct modulation by ovarian steroid receptors. Neuroscience. 2009 Mar 03; 159(1):204-16.
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Roma PG, Rinker JA, Serafine KM, Chen SA, Barr CS, Cheng K, Rice KC, Riley AL. Genetic and early environmental contributions to alcohol's aversive and physiological effects. Pharmacol Biochem Behav. 2008 Nov; 91(1):134-9.
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Jenab S, Festa ED, Russo SJ, Wu HB, Inturrisi CE, Quinones-Jenab V. MK-801 attenuates cocaine induction of c-fos and preprodynorphin mRNA levels in Fischer rats. Brain Res Mol Brain Res. 2003 Oct 07; 117(2):237-9.
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Jenab S, Niyomchai T, Chin J, Festa ED, Russo SJ, Perrotti LI, Quinones-Jenab V. Effects of cocaine on c-fos and preprodynorphin mRNA levels in intact and ovariectomized Fischer rats. Brain Res Bull. 2002 Jul; 58(3):295-9.
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Datta U, Noailles PA, Kraft M, Zhang Y, Angulo JA. Concurrent elevation of the levels of expression of striatal preproenkephalin and preprodynorphin mRNA in the rat brain by chronic treatment with caffeine. Neurosci Lett. 1997 Aug 01; 231(1):29-32.
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Angulo JA, Williams A, Ledoux M, Watanabe Y, McEwen BS. Elevation of striatal and accumbal preproenkephalin, preprotachykinin and preprodynorphin mRNA abundance subsequent to N-methyl-D-aspartate receptor blockade with MK-801. Brain Res Mol Brain Res. 1995 Mar; 29(1):15-22.
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Angulo JA, McEwen BS. Molecular aspects of neuropeptide regulation and function in the corpus striatum and nucleus accumbens. Brain Res Brain Res Rev. 1994 Jan; 19(1):1-28.