"Cyclosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
Descriptor ID |
D003524
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MeSH Number(s) |
D04.345.566.235 D12.644.641.235
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclosporins".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporins".
This graph shows the total number of publications written about "Cyclosporins" by people in this website by year, and whether "Cyclosporins" was a major or minor topic of these publications.
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Below are the most recent publications written about "Cyclosporins" by people in Profiles.
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R?os-Olivares E, Orraca ZM, Carrasco-Canales JA, Alvarado L, Marchand AM, Col?n JI. Characterization of the antitumor activity of a polyantigenic immunomodulator (PAI): I--Utilization of cimetidine and cyclosporine A. Bol Asoc Med P R. 1989 Jul; 81(7):246-53.
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Frederick WR, Callender CO, Saxinger CW, Flores JC, Alexander SS, Barnes SE, Flagg R, Walters CS, Dunston GM, Greaves WL. Serologic and immunologic correlates of retroviral infection in transplant recipients. Transplant Proc. 1989 Feb; 21(1 Pt 2):2093-6.
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Matsumoto Y, Perry G, Scheibel LW, Aikawa M. Role of calmodulin in Plasmodium falciparum: implications for erythrocyte invasion by the merozoite. Eur J Cell Biol. 1987 Dec; 45(1):36-43.
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Walters C, Callender C, Dunston G, Flores J, Toliver L, Cruz I. Lymphokine production and lymphocyte subpopulations in 25 black transplant patients. Transplant Proc. 1987 Feb; 19(1 Pt 2):1549-50.