beta 2-Microglobulin

"beta 2-Microglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants.

Descriptor ID	D001613
MeSH Number(s)	D12.776.124.790.223.100 D12.776.377.715.182.100
Concept/Terms	beta 2-Microglobulin beta 2-Microglobulin 2-Microglobulin, beta beta 2 Microglobulin Thymotaxin

Below are MeSH descriptors whose meaning is more general than "beta 2-Microglobulin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Serum Globulins [D12.776.124.790]
Beta-Globulins [D12.776.124.790.223]
beta 2-Microglobulin [D12.776.124.790.223.100]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Beta-Globulins [D12.776.377.715.182]
beta 2-Microglobulin [D12.776.377.715.182.100]

Below are MeSH descriptors whose meaning is related to "beta 2-Microglobulin".

Below are MeSH descriptors whose meaning is more specific than "beta 2-Microglobulin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "beta 2-Microglobulin" by people in this website by year, and whether "beta 2-Microglobulin" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1997 and 1999 and 2002 and 2003 and 2004 and 2008

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1997	1	1
1999	1	1
2002	1	1
2003	1	1
2004	1	1
2008	1	1

Below are the most recent publications written about "beta 2-Microglobulin" by people in Profiles.

Li W, Murthy AK, Guentzel MN, Seshu J, Forsthuber TG, Zhong G, Arulanandam BP. Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection. J Immunol. 2008 Mar 01; 180(5):3375-82.

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Garcia-Garcia I, Gonzalez-Delgado CA, Valenzuela-Silva C, Hernandez-Bernal F, Ferrero-Bibilonia J, Soto-Hernandez R, Cervantes-Llano M, Ducong? J, Correa-Fernandez A, Olivera-Ruano L, Lopez-Saura P. Bioequivalence of two recombinant interferon alpha-2b liquid formulations in healthy male volunteers. Drugs R D. 2004; 5(5):271-80.

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Elewaut D, Shaikh RB, Hammond KJ, De Winter H, Leishman AJ, Sidobre S, Turovskaya O, Prigozy TI, Ma L, Banks TA, Lo D, Ware CF, Cheroutre H, Kronenberg M. NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells. J Exp Med. 2003 Jun 16; 197(12):1623-33.

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Garc?a P, Llano M, de Heredia AB, Willberg CB, Caparr?s E, Aparicio P, Braud VM, L?pez-Botet M. Human T cell receptor-mediated recognition of HLA-E. Eur J Immunol. 2002 04; 32(4):936-44.

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Porto G, Cardoso CS, Gordeuk V, Cruz E, Fraga J, Areias J, Oliveira JC, Bravo F, Gangaidzo IT, MacPhail AP, Gomo ZA, Moyo VM, Melo G, Silva C, Justi?a B, de Sousa M. Clinical and genetic heterogeneity in hereditary haemochromatosis: association between lymphocyte counts and expression of iron overload. Eur J Haematol. 2001 Aug; 67(2):110-8.

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Plaeger S, Bermudez S, Mikyas Y, Harawa N, Dickover R, Mark D, Dillon M, Bryson YJ, Boyer PJ, Sinsheimer JS. Decreased CD8 cell-mediated viral suppression and other immunologic characteristics of women who transmit human immunodeficiency virus to their infants. J Infect Dis. 1999 Jun; 179(6):1388-94.

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Mikyas Y, Aziz N, Harawa N, Gorre M, Neagos N, Nogueira M, Wafer D, Dillon M, Boyer PJ, Bryson YJ, Plaeger S. Immunologic activation during pregnancy: serial measurement of lymphocyte phenotype and serum activation molecules in HIV-infected and uninfected women. J Reprod Immunol. 1997 Jun; 33(2):157-70.

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G?ssow D, Rein R, Ginjaar I, Hochstenbach F, Seemann G, Kottman A, Ploegh HL. The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit. J Immunol. 1987 Nov 01; 139(9):3132-8.

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