"Porphobilinogen Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the formation of porphobilinogen from two molecules of 5-aminolevulinic acid. EC 4.2.1.24.
| Descriptor ID |
D000623
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| MeSH Number(s) |
D08.811.520.241.300.550
|
| Concept/Terms |
Porphobilinogen Synthase- Porphobilinogen Synthase
- Synthase, Porphobilinogen
- Aminolevulinate Hydro-Lyase
- Aminolevulinate Hydro Lyase
- Hydro-Lyase, Aminolevulinate
- delta-Aminolevulinate Dehydratase
- Dehydratase, delta-Aminolevulinate
- delta Aminolevulinate Dehydratase
- delta-Aminolevulinic Acid Dehydratase
- Acid Dehydratase, delta-Aminolevulinic
- Dehydratase, delta-Aminolevulinic Acid
- delta Aminolevulinic Acid Dehydratase
- ALA-Dehydrase
- ALA Dehydrase
- Aminolevulinic Acid Dehydratase
- Acid Dehydratase, Aminolevulinic
- Dehydratase, Aminolevulinic Acid
|
Below are MeSH descriptors whose meaning is more general than "Porphobilinogen Synthase".
Below are MeSH descriptors whose meaning is more specific than "Porphobilinogen Synthase".
This graph shows the total number of publications written about "Porphobilinogen Synthase" by people in this website by year, and whether "Porphobilinogen Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Porphobilinogen Synthase" by people in Profiles.
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Sobin C, Flores-Montoya MG, Gutierrez M, Parisi N, Schaub T. d-Aminolevulinic acid dehydratase single nucleotide polymorphism 2 (ALAD2) and peptide transporter 2*2 haplotype (hPEPT2*2) differently influence neurobehavior in low-level lead exposed children. Neurotoxicol Teratol. 2015 Jan-Feb; 47:137-45.
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Sobin C, Parisi N, Schaub T, Gutierrez M, Ortega AX. d-Aminolevulinic acid dehydratase single nucleotide polymorphism 2 and peptide transporter 2*2 haplotype may differentially mediate lead exposure in male children. Arch Environ Contam Toxicol. 2011 Oct; 61(3):521-9.
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Sobin C, Gutierrez M, Alterio H. Polymorphisms of delta-aminolevulinic acid dehydratase (ALAD) and peptide transporter 2 (PEPT2) genes in children with low-level lead exposure. Neurotoxicology. 2009 Nov; 30(6):881-7.
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Dwyer BE, Smith MA, Richardson SL, Perry G, Zhu X. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease. Neurosci Lett. 2009 Aug 28; 460(2):180-4.