Lead Poisoning, Nervous System, Childhood
"Lead Poisoning, Nervous System, Childhood" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neurologic disorders occurring in children following lead exposure. The most frequent manifestation of childhood lead toxicity is an encephalopathy associated with chronic ingestion of lead that usually presents between the ages of 1 and 3 years. Clinical manifestations include behavioral changes followed by lethargy; CONVULSIONS; HALLUCINATIONS; DELIRIUM; ATAXIA; and vomiting. Elevated intracranial pressure (HYPERTENSION, INTRACRANIAL) and CEREBRAL EDEMA may occur. (From Adams et al., Principles of Neurology, 6th ed, p1210-2)
| Descriptor ID |
D020264
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| MeSH Number(s) |
C10.720.475.400.700 C25.723.522.750.500.700
|
| Concept/Terms |
Lead Poisoning, Nervous System, Childhood- Lead Poisoning, Nervous System, Childhood
- Poisoning, Lead, Neurologic, Childhood
- Lead-Induced Nervous System Disease, Childhood
- Lead Induced Nervous System Disease, Childhood
- Plumbism, Neurologic, Childhood
- Nervous System Poisoning, Lead, Childhood
- Lead Poisoning, Neurologic, Childhood
- Neurologic Saturnism, Childhood
- Childhood Neurologic Saturnism
- Saturnism, Childhood Neurologic
- Neurotoxicity Syndrome, Lead, Childhood
- Poisoning, Lead, Nervous System, Childhood
- Nervous System Disease, Lead-Induced, Childhood
Lead Encephalopathy, Childhood- Lead Encephalopathy, Childhood
- Childhood Lead Encephalopathy
- Encephalopathy, Childhood Lead
- Saturine Encephalopathy, Childhood
- Childhood Saturine Encephalopathy
- Encephalopathy, Childhood Saturine
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Below are MeSH descriptors whose meaning is more general than "Lead Poisoning, Nervous System, Childhood".
Below are MeSH descriptors whose meaning is more specific than "Lead Poisoning, Nervous System, Childhood".
This graph shows the total number of publications written about "Lead Poisoning, Nervous System, Childhood" by people in this website by year, and whether "Lead Poisoning, Nervous System, Childhood" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lead Poisoning, Nervous System, Childhood" by people in Profiles.
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Flores-Montoya MG, Bill CA, Vines CM, Sobin C. Early chronic low-level lead exposure reduced C-C chemokine receptor 7 in hippocampal microglia. Toxicol Lett. 2019 Oct 10; 314:106-116.
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Dominguez S, Flores-Montoya MG, Sobin C. Early chronic exposure to low-level lead alters total hippocampal microglia in pre-adolescent mice. Toxicol Lett. 2019 Mar 01; 302:75-82.
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Flores-Montoya MG, Alvarez JM, Sobin C. Olfactory recognition memory is disrupted in young mice with chronic low-level lead exposure. Toxicol Lett. 2015 Jul 02; 236(1):69-74.
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Flores-Montoya MG, Sobin C. Early chronic lead exposure reduces exploratory activity in young C57BL/6J mice. J Appl Toxicol. 2015 Jul; 35(7):759-65.
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Sobin C, Parisi N, Schaub T, de la Riva E. A Bland-Altman comparison of the Lead Care? System and inductively coupled plasma mass spectrometry for detecting low-level lead in child whole blood samples. J Med Toxicol. 2011 Mar; 7(1):24-32.
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Sobin C, Gutierrez M, Alterio H. Polymorphisms of delta-aminolevulinic acid dehydratase (ALAD) and peptide transporter 2 (PEPT2) genes in children with low-level lead exposure. Neurotoxicology. 2009 Nov; 30(6):881-7.
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Hamilton S, Rothenberg SJ, Khan FA, Manalo M, Norris KC. Neonatal lead poisoning from maternal pica behavior during pregnancy. J Natl Med Assoc. 2001 Sep; 93(9):317-9.