Acetylcysteine

"Acetylcysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.

Descriptor ID	D000111
MeSH Number(s)	D02.886.030.230.259 D12.125.166.230.259
Concept/Terms	Acetylcysteine Acetylcysteine N-Acetyl-L-cysteine N Acetyl L cysteine N-Acetylcysteine N Acetylcysteine Mercapturic Acid Acid, Mercapturic Solmucol Solmucol Genac Acemuc Acemuc Acetabs Acetabs Acetylcystein AL Acetylcystein AL NAC AL Acetylcystein Atid Acetylcystein Atid Acetylcystein Heumann Acetylcystein Heumann Acetylcystein Trom Acetylcystein Trom Acetylcysteine Hydrochloride Acetylcysteine Hydrochloride Hydrochloride, Acetylcysteine Acetylcysteine Sodium Acetylcysteine Sodium Sodium, Acetylcysteine Acetylcysteine, Monosodium Salt Monosodium Salt Acetylcysteine Acetylcysteine Zinc Acetylcysteine Zinc Zinc, Acetylcysteine Acetylcysteine, (D)-Isomer Acetylcysteine, (D)-Isomer Acetylcysteine, (DL)-Isomer Acetylcysteine, (DL)-Isomer Acetylcysteine, Monoammonium Salt Acetylcysteine, Monoammonium Salt Monoammonium Salt Acetylcysteine Acetyst Acetyst Acétylcystéine GNR Acétylcystéine GNR Airbron Airbron Alveolex Alveolex Bromuc Azubronchin Azubronchin Bisolvon NAC Bisolvon NAC NAC, Bisolvon Broncho-Fips Broncho-Fips Broncho Fips BronchoFips Broncholysin Broncholysin Broncoclar Broncoclar Codotussyl Codotussyl Cystamucil Cystamucil Dampo Mucopect Dampo Mucopect Mucopect, Dampo durabronchal durabronchal Larylin NAC Eurespiran Eurespiran Exomuc Exomuc Fluimucil Fluimucil NAC Zambon Zambon, NAC Fabrol Fabrol Fluprowit Fluprowit Optipect Hustengetränk Hustengetränk, Optipect Muco Sanigen Sanigen, Muco Frekatuss Frekatuss Jenacystein Jenacystein Jenapharm Lantamed Lantamed Lindocetyl Lindocetyl M-Pectil M-Pectil M Pectil MPectil mentopin Acetylcystein mentopin Acetylcystein Acetylcystein, mentopin Muciteran Muciteran Mucomyst Mucomyst Acetylin Mucosil Mucosil Mucosol Mucosolvin Mucosolvin Siccoral Siccoral Siran Ilube Ilube Hoestil Hoestil acebraus acebraus

Below are MeSH descriptors whose meaning is more general than "Acetylcysteine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Amino Acids, Sulfur [D02.886.030]
Cysteine [D02.886.030.230]
Acetylcysteine [D02.886.030.230.259]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Amino Acids, Sulfur [D12.125.166]
Cysteine [D12.125.166.230]
Acetylcysteine [D12.125.166.230.259]

Below are MeSH descriptors whose meaning is related to "Acetylcysteine".

Below are MeSH descriptors whose meaning is more specific than "Acetylcysteine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Acetylcysteine" by people in this website by year, and whether "Acetylcysteine" was a major or minor topic of these publications.

Bar chart showing 41 publications over 18 distinct years, with a maximum of 5 publications in 2009 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	2	0	2
2002	2	0	2
2003	1	0	1
2004	1	1	2
2006	1	0	1
2007	2	1	3
2008	2	2	4
2009	3	2	5
2010	5	0	5
2011	1	0	1
2012	1	1	2
2013	3	0	3
2014	1	0	1
2015	2	2	4
2016	0	1	1
2017	0	2	2
2018	0	1	1
2022	0	1	1

Below are the most recent publications written about "Acetylcysteine" by people in Profiles.

Morales-Borges RH, Gonzalez MJ, Duconge J, Minich DM. N-Acetyl Cysteine and Glutathione in Health and Cancer-Pharmacogenomics, Research, and Clinical Practice: Hypothesis and Review. Altern Ther Health Med. 2022 Oct; 28(7):169-177.

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Maiwall R, Kumar A, Bhadoria AS, Jindal A, Kumar G, Bhardwaj A, Maras JS, Sharma MK, Sharma BC, Sarin SK. Utility of N-acetylcysteine in ischemic hepatitis in cirrhotics with acute variceal bleed: a randomized controlled trial. Hepatol Int. 2020 Jul; 14(4):577-586.

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Musa MA, Gbadebo AJ, Latinwo LM, Badisa VL. 7,8-Dihydroxy-3-(4-nitrophenyl)coumarin induces cell death via reactive oxygen species-independent S-phase cell arrest. J Biochem Mol Toxicol. 2018 Dec; 32(12):e22203.

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Boldry EJ, Patel YM, Kotapati S, Esades A, Park SL, Tiirikainen M, Stram DO, Le Marchand L, Tretyakova N. Genetic Determinants of 1,3-Butadiene Metabolism and Detoxification in Three Populations of Smokers with Different Risks of Lung Cancer. Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1034-1042.

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Tan WJT, Song L, Graham M, Schettino A, Navaratnam D, Yarbrough WG, Santos-Sacchi J, Ivanova AV. Novel Role of the Mitochondrial Protein Fus1 in Protection from Premature Hearing Loss via Regulation of Oxidative Stress and Nutrient and Energy Sensing Pathways in the Inner Ear. Antioxid Redox Signal. 2017 09 10; 27(8):489-509.

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Guo ZN, Xu L, Hu Q, Matei N, Yang P, Tong LS, He Y, Guo Z, Tang J, Yang Y, Zhang JH. Hyperbaric Oxygen Preconditioning Attenuates Hemorrhagic Transformation Through Reactive Oxygen Species/Thioredoxin-Interacting Protein/Nod-Like Receptor Protein 3 Pathway in Hyperglycemic Middle Cerebral Artery Occlusion Rats. Crit Care Med. 2016 06; 44(6):e403-11.

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Odewumi CO, Latinwo LM, Ruden ML, Badisa VL, Fils-Aime S, Badisa RB. Modulation of cytokines and chemokines expression by NAC in cadmium chloride treated human lung cells. Environ Toxicol. 2016 Nov; 31(11):1612-1619.

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Yoshimoto T, Fujita T, Kajiya M, Matsuda S, Ouhara K, Shiba H, Kurihara H. Involvement of smad2 and Erk/Akt cascade in TGF-?1-induced apoptosis in human gingival epithelial cells. Cytokine. 2015 Sep; 75(1):165-73.

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Rodr?guez-Cotto RI, Ortiz-Mart?nez MG, Jim?nez-V?lez BD. Organic extracts from African dust storms stimulate oxidative stress and induce inflammatory responses in human lung cells through Nrf2 but not NF-?B. Environ Toxicol Pharmacol. 2015 Mar; 39(2):845-56.

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Badisa RB, Kumar SS, Mazzio E, Haughbrook RD, Allen JR, Davidson MW, Fitch-Pye CA, Goodman CB. N-acetyl cysteine mitigates the acute effects of cocaine-induced toxicity in astroglia-like cells. PLoS One. 2015; 10(1):e0114285.

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