Development of a novel UPLC-MS/MS method for the simultaneous quantification of mycophenolic mofetil, mycophenolic acid, and its major metabolites: Application to pharmacokinetic and tissue distribution study in rats.

Etim I, Abasifreke B, Sun R, Kuddabujja D, Liang D, Du T, Gao S. Development of a novel UPLC-MS/MS method for the simultaneous quantification of mycophenolic mofetil, mycophenolic acid, and its major metabolites: Application to pharmacokinetic and tissue distribution study in rats. J Pharm Biomed Anal. 2023 Sep 20; 234:115504.

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subject areas

Animals
Chromatography, High Pressure Liquid
Chromatography, Liquid
Glucuronides
Methanol
Mycophenolic Acid
Rats
Tandem Mass Spectrometry
Tissue Distribution

authors with profiles

Dong Liang

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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