Glucuronides

"Glucuronides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Glycosides of GLUCURONIC ACID formed by the reaction of URIDINE DIPHOSPHATE GLUCURONIC ACID with certain endogenous and exogenous substances. Their formation is important for the detoxification of drugs, steroid excretion and BILIRUBIN metabolism to a more water-soluble compound that can be eliminated in the URINE and BILE.

Descriptor ID	D020719
MeSH Number(s)	D02.241.081.844.915.162.500 D02.241.152.811.162.750 D02.241.511.902.915.162.750 D09.811.922.162.750
Concept/Terms	Glucuronides Glucuronides

Below are MeSH descriptors whose meaning is more general than "Glucuronides".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Acyclic [D02.241.081]
Sugar Acids [D02.241.081.844]
Uronic Acids [D02.241.081.844.915]
Glucuronates [D02.241.081.844.915.162]
Glucuronides [D02.241.081.844.915.162.500]
Acids, Aldehydic [D02.241.152]
Uronic Acids [D02.241.152.811]
Glucuronates [D02.241.152.811.162]
Glucuronides [D02.241.152.811.162.750]
Hydroxy Acids [D02.241.511]
Sugar Acids [D02.241.511.902]
Uronic Acids [D02.241.511.902.915]
Glucuronates [D02.241.511.902.915.162]
Glucuronides [D02.241.511.902.915.162.750]
Carbohydrates [D09]
Sugar Acids [D09.811]
Uronic Acids [D09.811.922]
Glucuronates [D09.811.922.162]
Glucuronides [D09.811.922.162.750]

Below are MeSH descriptors whose meaning is related to "Glucuronides".

Below are MeSH descriptors whose meaning is more specific than "Glucuronides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Glucuronides" by people in this website by year, and whether "Glucuronides" was a major or minor topic of these publications.

Bar chart showing 10 publications over 8 distinct years, with a maximum of 2 publications in 2012 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2012	2	0	2
2015	0	1	1
2018	1	0	1
2021	0	1	1
2022	0	1	1
2023	1	1	2
2024	1	0	1
2025	0	1	1

Below are the most recent publications written about "Glucuronides" by people in Profiles.

Asare E, Du T, Xie H, Liang D, Gao S. Biopharmaceutical Factors Involved in the Disposition of Mycophenolic Acid: A Comprehensive Review of ADME Properties and Their Potential Impact on Mycophenolic Acid Plasma Exposure. Curr Drug Metab. 2025; 26(3):159-172.

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Asare E, Emmanuel S, Du T, Xie H, Liang D, Gao S. Impact of Species and Tissue Differences on In Vitro Glucuronidation of Diclofenac. Molecules. 2024 Dec 12; 29(24).

View in: PubMed
Du Y, Li YY, Choi BY, Fernadez R, Su KJ, Sharma K, Qi L, Yin Z, Zhao Q, Shen H, Qiu C, Zhao LJ, Luo Z, Wu L, Tian Q, Deng HW. Metabolomic profiles associated with physical activity in White and African American adult men. PLoS One. 2023; 18(11):e0289077.

View in: PubMed
Etim I, Abasifreke B, Sun R, Kuddabujja D, Liang D, Du T, Gao S. Development of a novel UPLC-MS/MS method for the simultaneous quantification of mycophenolic mofetil, mycophenolic acid, and its major metabolites: Application to pharmacokinetic and tissue distribution study in rats. J Pharm Biomed Anal. 2023 Sep 20; 234:115504.

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Rincon Nigro ME, Du T, Gao S, Kaur M, Xie H, Olaleye OA, Liang D. Metabolite Identification of a Novel Anti-Leishmanial Agent OJT007 in Rat Liver Microsomes Using LC-MS/MS. Molecules. 2022 Apr 30; 27(9).

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Du T, Sun R, Siddiqui N, Moatamed L, Zhang Y, Liang D, Hu M, Gao S. A positive-negative switching LC-MS/MS method for quantification of fenoldopam and its phase II metabolites: Applications to a pharmacokinetic study in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Aug 01; 1179:122854.

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Murphy SE, von Weymarn LB, Parenteau M, Stepanov I, Tiirikainen M, LeMarchand L, Park SL. Influence of UGT2B10 Genotype on Urinary Excretion of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol- N-glucuronide by African American Smokers. Chem Res Toxicol. 2018 03 19; 31(3):168-175.

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Li F, Yang XW, Krausz KW, Nichols RG, Xu W, Patterson AD, Gonzalez FJ. Modulation of colon cancer by nutmeg. J Proteome Res. 2015 Apr 03; 14(4):1937-46.

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Grant DJ, Hoyo C, Oliver SD, Gerber L, Shuler K, Calloway E, Gaines AR, McPhail M, Livingston JN, Richardson RM, Schildkraut JM, Freedland SJ. Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk. Genet Test Mol Biomarkers. 2013 Jan; 17(1):3-9.

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Chen X, Peer CJ, Alfaro R, Tian T, Spencer SD, Figg WD. Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography-tandem mass spectrometry and its application to hepatic chemoembolization. J Pharm Biomed Anal. 2012 Mar 25; 62:140-8.

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