Altered functional properties of a TRPM2 variant in Guamanian ALS and PD.

Hermosura MC, Cui AM, Go RC, Davenport B, Shetler CM, Heizer JW, Schmitz C, Mocz G, Garruto RM, Perraud AL. Altered functional properties of a TRPM2 variant in Guamanian ALS and PD. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):18029-34.

View in: PubMed

subject areas

Adenosine Diphosphate Ribose
Amino Acid Sequence
Amino Acids, Diamino
Amyotrophic Lateral Sclerosis
Calcium
Calcium Signaling
Cell Membrane
Conserved Sequence
Evolution, Molecular
Guam
Humans
Hydrogen Peroxide
Ion Channel Gating
Leucine
Magnesium
Models, Molecular
Molecular Sequence Data
Mutant Proteins
Mutation
Oxidative Stress
Parkinsonian Disorders
Proline
Temperature
TRPM Cation Channels

authors with profiles

Meredith Hermosura

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support