Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy.

Akinboye ES, Brennen WN, Rosen DM, Bakare O, Denmeade SR. Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy. Prostate. 2016 Jun; 76(8):703-14.

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subject areas

Antineoplastic Agents
Cell Line, Tumor
Drug Design
Emetine
Endopeptidases
Gelatinases
Humans
Male
Membrane Proteins
Prodrugs
Prostatic Neoplasms
Serine Endopeptidases
Structure-Activity Relationship

authors with profiles

Oladapo Bakare

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