Selenomethionine reduces the deposition of beta-amyloid plaques by modulating ?-secretase and enhancing selenoenzymatic activity in a mouse model of Alzheimer's disease.

Zhang ZH, Chen C, Wu QY, Zheng R, Liu Q, Ni JZ, Hoffmann PR, Song GL. Selenomethionine reduces the deposition of beta-amyloid plaques by modulating ?-secretase and enhancing selenoenzymatic activity in a mouse model of Alzheimer's disease. Metallomics. 2016 08 01; 8(8):782-9.

View in: PubMed

subject areas

Alzheimer Disease
Amyloid Precursor Protein Secretases
Animals
Brain
Cells, Cultured
Disease Models, Animal
Gene Expression Regulation, Enzymologic
Mice
Mice, Transgenic
Selenomethionine
Selenoproteins

authors with profiles

Peter R. Hoffmann, PhD

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