Humanizing p-class glutathione S-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdose.

Vaughn MP, Biswal Shinohara D, Castagna N, Hicks JL, Netto G, De Marzo AM, Speed TJ, Reichert ZR, Kwabi-Addo B, Henderson CJ, Wolf CR, Yegnasubramanian S, Nelson WG. Humanizing p-class glutathione S-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdose. PLoS One. 2011; 6(10):e25707.

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subject areas

Acetaminophen
Animals
Biocatalysis
CpG Islands
Disease Models, Animal
DNA Methylation
Female
Glutathione S-Transferase pi
Humans
Liver
Male
Mice

authors with profiles

Bernard Kwabi-Addo

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