Relaxed Substrate Requirements of Sterol 14a-Demethylase from Naegleria fowleri Are Accompanied by Resistance to Inhibition.

Hargrove TY, Wawrzak Z, Rachakonda G, Nes WD, Villalta F, Guengerich FP, Lepesheva GI. Relaxed Substrate Requirements of Sterol 14a-Demethylase from Naegleria fowleri Are Accompanied by Resistance to Inhibition. J Med Chem. 2021 12 09; 64(23):17511-17522.

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subject areas

Ligands
Naegleria fowleri
Substrate Specificity

authors with profiles

Fernando Villalta

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